[Genes associated with early development, apoptosis and cell cycle regulation define a gene expression profile of adenoid cystic carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

Gene-disease associations manually curated.
DisGeNET evidence - CURATED

[Suppression of experimental autoimmune uveoretinitis by inducing differentiation of regulatory T cells via activation of aryl hydrocarbon receptor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Identification of genes potentially involved in the acquisition of androgen-independent and metastatic tumor growth in an autochthonous genetically engineered mouse prostate cancer model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[RECK level decreases as gliobastoma progresses, varying from less invasive grade II gliomas to very invasive human glioblastoma multiforme (GBM).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Targeting the nuclear factor-kappaB rescue pathway has promising future in human renal cell carcinoma therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Naringenin, a flavanone inhibits the proliferation of cerebrally implanted C6 glioma cells in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mycophenolic acid inhibits the phosphorylation of NF-kappaB and JNKs and causes a decrease in IL-8 release in H2O2-treated human renal proximal tubular cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Corticoid effects on angiotensin- and norepinephrine-induced proteinuria in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Withdrawal of clonidine: effects of varying dosage or duration of treatment on subsequent blood pressure and heart rate responses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Point mutations affecting the tyrosine kinase domain of the RET proto-oncogene in Hirschsprung's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Germline RET mutations in MEN 2A and FMTC and their detection by simple DNA diagnostic tests.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression profiles of hepatic cell-type specific marker genes in progression of liver fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Further evidence for association of the RGS2 gene with antipsychotic-induced parkinsonism: protective role of a functional polymorphism in the 3'-untranslated region.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[RGS9-2 negatively modulates L-3,4-dihydroxyphenylalanine-induced dyskinesia in experimental Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Blood gene expression markers to detect and distinguish target organ toxicity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Exome sequencing of liver fluke-associated cholangiocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A novel mitochondrial mutation, 1556C --> T, in a Japanese patient with streptomycin-induced tinnitus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Downregulation of ROCK-I and ROCK-II gene expression in the cadmium-induced ventral body wall defect chick model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in RPE65 cause early-onset blindness, and Rpe65-deficient mice lack 11-cis-retinal but overaccumulate alltrans-retinyl esters in the retinal pigment epithelium (RPE).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in RPE65 cause Leber's congenital amaurosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Here we report that the analysis of RPE65 in a collection of about 100 unselected retinal-dystrophy patients of different ethnic origin revealed five that are likely to be pathogenic mutations, including a missense mutation (Pro363Thr), two point mutations affecting splicing (912 + 1G-->T and 65 + 5G-->A) and two small re-arrangements (ins144T and 831del8) on a total of nine alleles of five patients with arCSRD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Null RPGRIP1 alleles in patients with Leber congenital amaurosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[An integrative approach to identify YB-1-interacting proteins required for cisplatin resistance in MCF7 and MDA-MB-231 breast cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Microarray analysis of gene expression in peripheral blood mononuclear cells from dioxin-exposed human subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Two genes identified in this manner, RUNX3 and Testin (TES), were subsequently shown to harbor frequent tumor-specific epigenetic alterations in primary glioblastomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Regulation of retinoic acid receptors alpha, beta and retinoid X receptor alpha after sciatic nerve injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Central core disease and malignant hyperthermia (MH) are both associated with mutations in the RYR1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reactive oxygen species/oxidative stress contributes to progression of kidney fibrosis following transient ischemic injury in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Our findings reinforce the role of astroglial cells in the pathogenesis of bipolar disorder and S100B protein as a marker of bipolar mania.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Methylmercury increases S100B content in rat cerebrospinal fluid.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Here we present 12 novel mutations in SALL1 associated with Townes-Brocks syndrome in 13 unrelated families.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A SALL4 zinc finger missense mutation predicted to result in increased DNA binding affinity is associated with cranial midline defects and mild features of Okihiro syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pneumotoxicity of dust from aluminum foundry and pure alumina: a comparative study of morphology and biomarkers in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Molecular evidence for differences in endometrium in severe versus mild endometriosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutation of sodium channel SCN3A in a patient with cryptogenic pediatric partial epilepsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Human sodium channel myotonia: slowed channel inactivation due to substitutions for a glycine within the III-IV linker.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We have studied a large (n=131) LQT-affected Jewish kindred and identified tight linkage between the LQT-affected status and LQT3 (lod score 6.13, with an estimated recombination fraction of zero).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in the beta-subunit of the epithelial Na+ channel in patients with a cystic fibrosis-like syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Here, we report a patient with SCO 2 mutations and with resolution of severe hypertrophic cardiomyopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Soluble E-selectin, von Willebrand factor, soluble thrombomodulin, and total body nitrate/nitrite product as indices of endothelial damage/dysfunction in paroxysmal, persistent, and permanent atrial fibrillation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol production.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The results demonstrated that SELENBP1 mRNA was upregulated in schizophrenic brains versus controls (P = 0.046) and, in addition, that SELENBP1 gene expression was strongly positively correlated with presence of psychosis across diagnoses (P < 0.001, increased by 12%).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Neurodegeneration in mice resulting from loss of functional selenoprotein P or its receptor apolipoprotein E receptor 2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Different transcriptional control of metabolism and extracellular matrix in visceral and subcutaneous fat of obese and rimonabant treated mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hepatocellular carcinoma-associated protein markers investigated by MALDI-TOF MS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[This new proposed phenotype for AAT transcends classic pattern of strictly liver and lung disease, and should be considered for proper evaluation and management of patients presenting with classic AAT-related disorders, affective disorders, persons with ICE, white matter disease or multisystem disorders of memory.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[ERE-independent ERalpha target genes differentially expressed in human breast tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Liver transcriptional profile of atherosclerosis-related genes in human nonalcoholic fatty liver disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Comparative proteomic analysis of esophageal squamous cell carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Right ventricular thrombosis due to familial heparin cofactor II deficiency].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[PPAR activation induces acute PAI-1 gene expression in the liver but not in adipose tissues of diabetic model mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Various classes of proteins were found either to be present or to be upregulated in keloid tissue: (i) inflammatory/differentiated keratinocyte markers: S100 proteins, peroxiredoxin I; (ii) wound healing proteins: gelsolin-like capping protein; (iii) fibrogenetic proteins: mast cell -tryptase, macrophage migration inhibitory factor (MIF); (iv) antifibrotic proteins: asporin; (v) tumour suppressor proteins: stratifin, galectin-1, maspin; and (vi) antiangiogenic proteins: pigment epithelium-derived factor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Moreover, methylation of APC1A, APC2, SFRP1, and SFRP2 appears to mark progression from IBD colitis to IBD-associated neoplasia, and these genes may serve as biomarkers for IBD-associated neoplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Intolerance to -blockade in a mouse model of -sarcoglycan-deficient muscular dystrophy cardiomyopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The podosomal-adaptor protein SH3PXD2B is essential for normal postnatal development.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Sociability and motor functions in Shank1 mutant mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Functional impact of global rare copy number variation in autism spectrum disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Three cases with a common breakpoint within SHANK3 share a number of common phenotypic features, such as mental retardation and developmental delay with severely delayed or absent expressive speech.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Polymorphisms in the SHBG gene are associated with risk of type 2 diabetes, but few studies have addressed SHBG as a predictor of CV events.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cisplatin induces Sirt1 in association with histone deacetylation and increased Werner syndrome protein in the kidney.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Resveratrol Targeting of Carcinogen-Induced Brain Endothelial Cell Inflammation Biomarkers MMP-9 and COX-2 is Sirt1-Independent.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Silent information regulator 1 protects the heart from ischemia/reperfusion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[To determine the role of NKCC1 in systemic vascular resistance and hypertension, blood pressure was measured in rats before and after inhibition of NKCC1 with bumetanide.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Development of epileptiform excitability in the deep entorhinal cortex after status epilepticus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Folate pathway and nonsyndromic cleft lip and palate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Analysis of seven maternal polymorphisms of genes involved in homocysteine/folate metabolism and risk of Down syndrome offspring.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[GPR30 regulates glutamate transporter GLT-1 expression in rat primary astrocytes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Urolithiasis and hepatotoxicity are linked to the anion transporter Sat1 in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Molecular analysis of the PDS gene in a nonconsanguineous Sicilian family with Pendred's syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The gene causing Pendred syndrome (PDS) encodes a protein designated pendrin, which is expressed in the thyroid, kidney, and fetal cochlea.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased transglutaminase 2 and GLUT-1 expression in breast tumors not susceptible to chemoprevention with antioxidants.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Preclinical rationale for use of the clinically available multitargeted tyrosine kinase inhibitor crizotinib in ROS1-translocated lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Prediction of nephrotoxicant action and identification of candidate toxicity-related biomarkers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A customized pigmentation SNP array identifies a novel SNP associated with melanoma predisposition in the SLC45A2 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Primary biliary cirrhosis (PBC) is a cholestatic disease associated with autoimmune phenomena and alterations in both biliary bicarbonate excretion and expression of the bicarbonate carrier AE2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Autosomal recessive proximal renal tubular acidosis is caused by mutations in the SLC4A4 gene encoding the electrogenic sodium bicarbonate cotransporter NBCe1-A.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The rat sodium iodide symporter gene permits more effective radioisotope concentration than the human sodium iodide symporter gene in human and rodent cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The human tumour suppressor gene SLC5A8 expresses a Na+-monocarboxylate cotransporter.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dopamine transporter genetic variants and pesticides in Parkinson's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Serotonin transporter linked promoter (polymorphism) in the serotonin transporter gene may be associated with antidepressant-induced mania in bipolar disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[X-linked creatine deficiency syndrome: a novel mutation in creatine transporter gene SLC6A8.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Creatine transporter deficiency is an X-linked mental retardation disorder caused by mutations in the creatine transporter gene, SLC6A8.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The glycine transporter 1 gene (GLYT1) is associated with methamphetamine-use disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cardioplegia prevents ischemia-induced transcriptional alterations of cytoprotective genes in rat hearts: a DNA microarray study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Here we report the identification of biallelic SLX4 mutations in two individuals with typical clinical features of Fanconi anemia and show that the cellular defects in these individuals' cells are complemented by wildtype SLX4, demonstrating that biallelic mutations in SLX4 (renamed here as FANCP) cause a new subtype of Fanconi anemia, Fanconi anemia-P.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression and location of Smad2, 4 mRNAs during and after liver fibrogenesis of rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genetic variations in the SMAD4 gene and gastric cancer susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The mutational landscape of adenoid cystic carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[As SMARCB1 encodes a subunit of the SWItch/Sucrose NonFermenting (SWI/SNF) complex, we screened 15 other genes encoding subunits of this complex in 23 individuals with CSS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Modulation of aromatase expression in human breast tissue.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Manganese superoxide dismutase induces migration and invasion of tongue squamous cell carcinoma via H2O2-dependent Snail signaling.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Synuclein gamma stimulates membrane-initiated estrogen signaling by chaperoning estrogen receptor (ER)-alpha36, a variant of ER-alpha.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reduced expression of TAC1, PENK and SOCS2 in Hcrtr-2 mutated narcoleptic dog brain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Transcriptional profiling in the lumbar spinal cord of a mouse model of amyotrophic lateral sclerosis: a role for wild-type superoxide dismutase 1 in sporadic disease?]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in Cu/Zn superoxide dismutase 1 (SOD1) have been linked to dominantly inherited forms of amyotrophic lateral sclerosis (FALS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Table 1 Biochemical Alterations in Substantia Nigra of Parkinson's Disease Indicating Oxidative Stress Elevated Decreased Iron (in microglia, astrocytes, oligodendrocytes, and melanized dopamine neurons and mitochondria) GSH (GSSG unchanged); GSH/GSSG ratio decreased Mitochondrial complex I Ferritin Calcium binding protein (calbindin 28) Mitochondrial monoamine oxidase B Transferrin and transferrin receptor Lipofuscin Vitamins E and C Ubiquitin Copper Cu/Zn-superoxide dismutase Cytotoxic cytokines (TNF-a, IL-1, IL-6) Inflammatory transcription factor NFKB Heme oxygenase-1 Ratio of oxidized to reduced glutathione (GSSG/GSH) Nitric oxide Neuromelanin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In emerging diabetic retinopathy, MEMRI provided an analytic measure of an ionic dysregulatory pattern that was sensitive to SOD1 overexpression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased expression of a proline-rich Akt substrate (PRAS40) in human copper/zinc-superoxide dismutase transgenic rats protects motor neurons from death after spinal cord injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Comparative proteome analysis of human adenocarcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[This study examined telomere biology in heart/muscle-specific manganese superoxide dismutase-deficient mice (H/M-SOD2(-/-)), which develop progressive congestive heart failure and exhibit pathology typical of dilated cardiomyopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression and prognostic significance of catalase in malignant mesothelioma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Alcohol increases tumor necrosis factor alpha and decreases nuclear factor-kappab to activate hepatic apoptosis in genetically obese mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased expression of manganese-superoxide dismutase in fibroblasts of patients with CPEO syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Molecular consequences of SOD2 expression in epigenetically silenced pancreatic carcinoma cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Modulation of radiation-induced cytokine elevation associated with esophagitis and esophageal stricture by manganese superoxide dismutase-plasmid/liposome (SOD2-PL) gene therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genetic polymorphisms of MPO, COMT, MnSOD, NQO1, interactions with environmental exposures and bladder cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of extracellular superoxide dismutase in hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A redox signature score identifies diffuse large B-cell lymphoma patients with a poor prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The small intestine proteome is changed in preterm pigs developing necrotizing enterocolitis in response to formula feeding.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Adenovirus-mediated inhibition of SPARC attenuates liver fibrosis in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Ten Aza-dC and/or TSA up-regulated genes (CPEB1, CD9, GJA1, BCL7c, GADD45G, AKAP12, TFPI2, CCNA1, SPARC, and BNIP3) were selected for methylation analysis in six MM cell lines, 24 samples from patients with monoclonal gammopathy of undetermined significance (MGUS), and 111 samples from patients with MM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Whether the defective expression of the osteonectin in fro/fro mice is due to a mutation in the gene itself or its regulatory site(s), or is secondary to other factors remains to be established.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Investigation of primary tumors revealed that the Sparc promoter is methylated in 68% of primary ovarian tumors and that the levels of SPARC protein decrease as the disease progresses from low to high grade.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Altered PU.1 function is possibly implicated in leukemogenesis, as PU.1 gene mutations were identified in some patients with acute myeloid leukemia (AML) and as several oncogenic products (AML1-ETO, promyelocytic leukemia-retinoic acid receptor alpha, FMS-like receptor tyrosine kinase 3 internal tandem duplication) are associated with PU.1 downregulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In an in vitro co-culture model of human Suit2-007 and rat AsML PDAC cells with rat hepatocytes, a clearly increased expression of OPN mRNA was found in the tumor cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Raloxifene attenuates Gas6 and apoptosis in experimental aortic valve disease in renal failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Varied pathways of stage IA lung adenocarcinomas discovered by integrated gene expression analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Localization and expression of cornifin-alpha/SPRR1 in mouse epidermis, anagen hair follicles, and skin neoplasms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression of genes involved in lipid metabolism in men with impaired glucose tolerance: impact of insulin stimulation and weight loss.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of intracerebral injections of somatostatin and neurotensin on motor functions in seizure].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Somatostatin receptor expression in a parathyroid hormone-related peptide-secreting pancreatic neuroendocrine tumour causing severe hypercalcaemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[STAT-3 is active during the regenerative growth of the liver, but there are hardly any data about its presence in liver tumours.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Aberrant expression of the transcriptional factor Twist1 promotes invasiveness in ALK-positive anaplastic large cell lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genes showing increased expression in carcinomas by cDNA microarray analysis (and further validated by immunohistochemistry and western blot analysis) include cyclin D1, PDGF-A chain, retinol binding protein 1, prohibitin and the transcription factor STAT5A.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome wide association for addiction: replicated results and comparisons of two analytic approaches.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression of VGLUTs contributes to degeneration and acquisition of learning and memory.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Chronic tobacco smoke exposure increases airway sensitivity to capsaicin in awake guinea pigs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Sensory neuron and substance P involvement in symptoms of a zymosan-induced rat model of acute bowel inflammation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Injection of substance P (SP) in a rat hindpaw induced extravasation of 125I-labelled albumin in both hindpaws and salivation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Among these identified proteins, 33 proteins including keratin 17 (KRT17), biliverdin reductase B (BLVRB), proteasome activator subunit 1 (PSME1), manganese superoxide dismutase (MnSOD), high-mobility group box-1(HMGB1), heat shock protein 70 (HSP70), peroxiredoxin (PRDX1), keratin 13 (KRT13), and so on were overexpressed, and 14 proteins including cystatin B (CSTB), tropomyosin 2 (TPM2), annexin 1 (ANX1), transgelin (TAGLN), keratin 19 (KRT19), stratifin (SFN), and so on were down-expressed in ESCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Improved toxicogenomic screening for drug-induced phospholipidosis using a multiplexed quantitative gene expression ArrayPlate assay.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[An integrated approach to proteome analysis: identification of proteins associated with cardiac hypertrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Here we report the identification of three variants in the RUNX3, LTBR-TNFRSF1A and IL12B regions convincingly associated with ankylosing spondylitis (P < 5 10(-8) in the combined discovery and replication datasets) and a further four loci at PTGER4, TBKBP1, ANTXR2 and CARD9 that show strong association across all our datasets (P < 5 10(-6) overall, with support in each of the three datasets studied).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[TCF4 mutational analysis was performed in 117 patients with PTHS-like features.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Haploinsufficiency of the gene encoding for transcription factor 4 (TCF4) was recently identified as the underlying cause of Pitt-Hopkins syndrome (PTHS), an underdiagnosed mental-retardation syndrome characterised by a distinct facial gestalt, breathing anomalies and severe mental retardation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Bayesian refinement of association signals for 14 loci in 3 common diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Subcellular localization of activated AKT in estrogen receptor- and progesterone receptor-expressing breast cancers: potential clinical implications.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutation in TECPR2 reveals a role for autophagy in hereditary spastic paraparesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Coronary artery disease and a functional polymorphism of hTERT.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Telomerase mutations in families with idiopathic pulmonary fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[p21 and mTERT are novel markers for determining different ischemic time periods in renal ischemia-reperfusion injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reduced TFAP2A function causes variable optic fissure closure and retinal defects and sensitizes eye development to mutations in other morphogenetic regulators.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[mRNA expression of iron regulatory genes in beta-thalassemia intermedia and beta-thalassemia major mouse models.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The transferrin receptor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In the TGF-alpha transgenic mouse model, TGF-alpha protects against nickel-induced acute lung injury, at least in part, by attenuating the inflammatory response, reducing pulmonary edema, and preserving levels of SP-B.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gefitinib (`Iressa`, ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression changes during the development of acute lung injury: role of transforming growth factor beta.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1 axis in db/db mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Disruption of TGF- signaling improves ocular surface epithelial disease in experimental autoimmune keratoconjunctivitis sicca.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Transforming growth factor beta1 enhances tumor promotion in mouse skin carcinogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Renoprotective effects of carvedilol in hypertensive-stroke prone rats may involve inhibition of TGF beta expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Divergent effects of low versus high dose anti-TGF-beta antibody in puromycin aminonucleoside nephropathy in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[HNPCC associated with germline mutation in the TGF-beta type II receptor gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Methylation silencing of transforming growth factor-beta receptor type II in rat prostate cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Discovery of deregulation of zinc homeostasis and its associated genes in esophageal squamous cell carcinoma using cDNA microarray.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The authors report the long-term course of two siblings with L-dopa responsive dystonia (DRD) associated with a compound heterozygous mutation in the tyrosine hydroxylase (TH) gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The first mutation identified in the thrombomodulin gene in a 45-year-old man presenting with thromboembolic disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of furosemide infusion on renal hemodynamics and angiogenesis gene expression in acute renal ischemia/reperfusion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Knockdown of ICB-1 gene enhanced estrogen responsiveness of ovarian and breast cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Correlation between TIMP-1 expression and liver fibrosis in two rat liver fibrosis models.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Oral submucous fibrosis: review on aetiology and pathogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Evidence favoring linkage was found at 2p24 and 14q11.2, and this led to the identification of TINF2 (14q11.2) mutations, K280E, in the proband and her five affected relatives and TINF2 R282H in three additional unrelated DC probands, including one with Revesz syndrome; a fifth DC proband had a R282S mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[(1) Expressions of TLR4, levels of TNF- and MMP-9 were increased and the rate was rising from the control group, to SAP group and then to ACS group.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In conclusion, we report an association of microsatelite GT polymorphisms of TLR2 gene and Asp299Gly polymorphism of the TLR4 gene with sporadic colorectal cancer among Croatians.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[There was no evidence that the above variants of the TLR2, TLR4 and TLR9 genes are major risk factors for CD or influence disease phenotype in our New Zealand case-control study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hypomorphic mutations in meckelin (MKS3/TMEM67) cause nephronophthisis with liver fibrosis (NPHP11).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression time course in the human skin during elicitation of allergic contact dermatitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Coding SNP in tenascin-C Fn-III-D domain associates with adult asthma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Analysis of TNF-alpha promoter polymorphisms in the susceptibility to beryllium hypersensitivity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[MEL exposure modulated the mitotic and apoptotic indices in the colonic adenocarcinomas that developed and lowered the immunohistochemical expression of nuclear factor kappa B, tumor necrosis factor alpha, interleukin-1beta and STAT3 in the epithelial malignancies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In this study, we showed that TNF induces EMT in human HCT116 cells and thereby promotes colorectal cancer (CRC) invasion and metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Involvement of tumor necrosis factor-alpha in sulfur mustard-induced skin lesion; effect of topical iodine.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Glucocorticoids play a fundamental role in protecting the brain during innate immune response.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cadmium-mediated toxicity of lung epithelia is enhanced through NF-B-mediated transcriptional activation of the human zinc transporter ZIP8.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORt cells in allergic inflammation, local lung distribution and chemokine gene expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reticulate scleroderma after isolated limb perfusion with melphalan.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Akt Cys-310-targeted inhibition by hydroxylated benzene derivatives is tightly linked to their immunosuppressive effects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects on tumour microcirculation in mice of misonidazole and tumour necrosis factor plus hyperthermia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gastric damage and granulocyte infiltration induced by indomethacin in tumour necrosis factor receptor 1 (TNF-R1) or inducible nitric oxide synthase (iNOS) deficient mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Association of TNF-alpha promoter polymorphisms with aspirin-induced urticaria.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mapatumumab, an antibody targeting TRAIL-R1, in combination with paclitaxel and carboplatin in patients with advanced solid malignancies: results of a phase I and pharmacokinetic study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Scan of 977 nonsynonymous SNPs in CLL4 trial patients for the identification of genetic variants influencing prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased damage of exon 5 of p53 gene in workers from an arsenic plant.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The pattern of modification followed the pattern of p53 mutations found in vinyl chloride-associated liver angiosarcomas in humans and rats, but only in regions that showed 100% homology with the human sequence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The KRAS2 mutation incidence was similar for spontaneous and asbestos-induced human lung tumors, while the TP53 mutation incidence differed significantly.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[DeltaNp63alpha confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased brain lysosomal pepstatin-insensitive proteinase activity in patients with neurodegenerative diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Functional assays showed reduced binding of this TRAF3IP2 variant to TRAF6, suggesting altered modulation of immunoregulatory signals through altered TRAF interactions as a new and shared pathway for PsA and PsV.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Modulation of hepatic granulomatous responses by transgene expression of DAP12 or TREM-1-Ig molecules.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Here, we report monoallelic frameshift or missense mutations and one 3' UTR variant of TREX1 present in 9/417 individuals with systemic lupus erythematosus but absent in 1,712 controls (P = 4.1 x 10(-7)).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of intracerebroventricular administration of thyrotrophic-releasing hormone on cardiovascular function in the rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Montirelin hydrate (NS-3), a TRH analog, improved the disturbance of consciousness caused by head concussion and pentobarbital in mice].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[HOXD10, HOXD11, HOXD13, CCL8 and LIM homeobox 2 were highly and exclusively expressed in RA and CLU, sarcoglycan-gamma, GPR64, POU3F3, peroxisome proliferative activated receptor-gamma and tripartite motif-containing 2 were expressed only in OA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mulibrey nanism (MUL) is an autosomal recessive disease caused by mutations in the TRIM37 gene encoding the peroxisomal TRIM37 protein of unknown function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Selenoprotein expression is essential in endothelial cell development and cardiac muscle function.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[MELAS syndrome in a patient with a point mutation in MTTS1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Our data suggest that TRPA1 is a key integrator of interactions between the immune and nervous systems in the airways, driving asthmatic airway inflammation following inhaled allergen challenge.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We conclude that acute acid induced oesophagitis is reduced in animals lacking VR-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[We originally described a large New England family of French-Canadian origin with SPSMA and an American family of English and Scottish descent with CMT2C.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Tuberous sclerosis complex (TSC) is an autosomal dominant neurogenetic disorder caused by mutations in one of two genes, TSC1 or TSC2, which encode the proteins hamartin and tuberin, respectively 123.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[tRNA splicing endonuclease mutations cause pontocerebellar hypoplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Brief report: congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[TTR tetramer dissociation is an initial step for the process of TTR-derived amyloid fibril formation associated with FAP and diflinisal can inhibit this process by stabilization of the TTR tetramer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Screening and identification of differential serum proteins related to dermatitis medicamentosa-like of trichloroethylene].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Our study suggests that genetic variants at or near the SEPP1 and TXNRD1 loci may be associated with advanced colorectal adenoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of thymidine phosphorylase and orotate phosphoribosyltransferase mRNA expression and its ratio to dihydropyrimidine dehydrogenase in the prognosis and clinicopathological features of patients with pancreatic cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Genetic polymorphisms associated with 5-Fluorouracil-induced neurotoxicity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Thymidylate synthase haplotype is associated with tumor recurrence in stage II and stage III colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Thymidylate synthase and microsatellite instability in colorectal cancer: implications for disease free survival, treatment response and survival with metastases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Methotrexate-induced subacute neurotoxicity in a child with acute lymphoblastic leukemia carrying genetic polymorphisms related to folate homeostasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Discrimination of tumorigenic triazole conazoles from phenobarbital by transcriptional analyses of mouse liver gene expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[GABAA receptor beta3 subunit gene-deficient heterozygous mice show parent-of-origin and gender-related differences in beta3 subunit levels, EEG, and behavior.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Salicylate nephropathy in the Gunn rat: potential role of prostaglandins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Association between polymorphisms in HSD3B1 and UGT2B17 and prostate cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Allowing for sex differences increases power in a GWAS of multiplex Autism families.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Here we identify URI, which encodes a mitochondrial inhibitor of PP1 and PP1-mediated feedback inhibition of S6K1-BAD survival signaling, as an oncogene amplified and overexpressed in ovarian cancer cell lines and human ovarian carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Porphyria cutanea tarda (PCT) is a metabolic disorder of heme biosynthesis, characterized by reduced uroporphyrinogen decarboxylase (UROD) activity and increased urinary excretion of eight and seven carboxyl group porphyrins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Missense mutation in the USH2A gene: association with recessive retinitis pigmentosa without hearing loss.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutational spectrum in Usher syndrome type II.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Behavioral effects of urotensin-II centrally administered in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Benazepril, an angiotensin-converting enzyme inhibitor, alleviates renal injury in spontaneously hypertensive rats by inhibiting advanced glycation end-product-mediated pathways.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[These findings indicate that the increase of VDAC1 and the decrease of VDAC2 play an important role during the process and provide new molecular evidence in understanding mechanism of refractory epilepsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A Phase I trial of calcitriol (1,25-dihydroxycholecalciferol) in patients with advanced malignancy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Tumor progression in the LPB-Tag transgenic model of prostate cancer is altered by vitamin D receptor and serum testosterone status.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Rapid regression of disc neovascularization in a patient with proliferative diabetic retinopathy following adjunctive intravitreal bevacizumab.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[These results indicate an arteriogenic effect of VEGF in a large mammalian model of myocardial ischemia and encourage the use of VEGF to promote arteriolar growth in patients with severe coronary artery disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[High vascular endothelial growth factor (VEGF) expression in chemically-induced hepatic microcancers in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[COX-2 over-expression can up-regulate the expression of VEGF-C. VEGF-C might promote lymph node metastasis by a lymph-angiogenic pathway, then affect the prognosis of the patients with breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Synovial sarcoma after chemotherapy for osteosarcoma: a case report.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Excitotoxicity in the lung: N-methyl-D-aspartate-induced, nitric oxide-dependent, pulmonary edema is attenuated by vasoactive intestinal peptide and by inhibitors of poly(ADP-ribose) polymerase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The Thr224Asn mutation in the VPS45 gene is associated with the congenital neutropenia and primary myelofibrosis of infancy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[VSX1: a gene for posterior polymorphous dystrophy and keratoconus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[SNPs at WDR36, IL33 and MYB that showed suggestive association with eosinophil counts were also associated with atopic asthma (P = 4.2 x 10(-6), 2.2 x 10(-5) and 2.4 x 10(-4), respectively).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Results indicated that WT1 silencing adversely affected glioblastoma viability, at times, in synergy with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and cisplatin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Patients with CN-AML harboring mutations in NPM1, FLT3, CEBPA, WT1 or expressing high levels of BAALC, ERG, or MN1 have distinctly different clinical outcomes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A novel point mutation in the McLeod syndrome gene in neuroacanthocytosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Single nucleotide polymorphisms in DNA repair genes and basal cell carcinoma of skin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In esophageal cancer patients, none of the polymorphisms studied had conclusive results in multivariate analysis, although XRCC3 variant (rs861539) showed an effect on survival in Kaplan-Meier univariate analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Akt activation is responsible for enhanced migratory and invasive behavior of arsenic-transformed human bronchial epithelial cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pleiotropic and diverse expression of ZFHX1B gene transcripts during mouse and human development supports the various clinical manifestations of the `Mowat-Wilson` syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Global analysis of differentially expressed genes in androgen-independent prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Craniofacial, skeletal, and cardiac defects associated with altered embryonic murine Zic3 expression following targeted insertion of a PGK-NEO cassette.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[These observations suggest focal segmental glomerulosclerosis as a phenotypic manifestation in patients with ZMPSTE24 deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

Gene-disease associations inferred from animal model manually asserted gene-disease associations.
DisGeNET evidence - PREDICTED

[The ratio of ELR+ to ELR- CXC chemokines affects the lung and liver injury following hepatic ischemia/ reperfusion in the rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Neutrophil chemokines and their role in IL-18-mediated increase in neutrophil O2- production and intestinal edema following alcohol intoxication and burn injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Differential changes in the concentrations of cytokine-induced neutrophil chemoattractant (CINC)-1 and CINC-2 in exudate during rat lipopolysaccharide-induced inflammation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pharmacological characterization of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103), a novel selective 5-lipoxygenase-activating protein inhibitor that reduces acute and chronic inflammation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cyclooxygenase-2/prostaglandin D2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Ang-(1-7) might prevent the development of monocrotaline induced pulmonary arterial hypertension in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The relationship between leukemia inhibitory factor and neurokinin receptors in a rat model of asthma].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CXCR3 blockade inhibits T-cell migration into the CNS during EAE and prevents development of adoptively transferred, but not actively induced, disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression of serine protease inhibitor 3 in ocular tissues in endotoxin-induced uveitis in rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Two-domain MHC class II molecules form stable complexes with myelin basic protein 69-89 peptide that detect and inhibit rat encephalitogenic T cells and treat experimental autoimmune encephalomyelitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Rapid clearance of circulating haptoglobin from plasma during acute pulmonary embolism in rats results in HMOX1 up-regulation in peripheral blood leukocytes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Attenuation of chronic hypoxic pulmonary hypertension by simvastatin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inducible transgenic rat model for diabetes mellitus based on shRNA-mediated gene knockdown.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Differential effects of selective endothelin type a receptor antagonist on the gene expression of vascular endothelial growth factor and its receptors in streptozotocin-induced diabetic heart.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inhibition of VEGFR2 prevents DMBA-induced mammary tumor formation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression of stromal cell-derived factor 1 is increased in the retina of experimental diabetic rats].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Time course of vascular arginase expression and activity in spontaneously hypertensive rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Vesicular monoamine transporter-2 and aromatic L-amino acid decarboxylase gene therapy prevents development of motor complications in parkinsonian rats after chronic intermittent L-3,4-dihydroxyphenylalanine administration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Induction of the proinflammatory cytokine interleukin-18 by axonal injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A novel rat model to determine interaction between reflux oesophagitis and bronchial asthma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of inflammatory cytokines and chemoattractants in the rat model of streptozotocin-induced diabetic heart failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[UCP2 and UCP3 gene expression, heart function and oxygen cost of myocardial work changes during aging and ischemia-reperfusion].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Beta2-Adrenergic agonists suppress rat autoimmune myocarditis: potential role of beta2-adrenergic stimulants as new therapeutic agents for myocarditis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression profiling and functional proteomic analysis reveal perturbed kinase-mediated signaling in genetic stroke susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Occlusal disharmony increases amyloid- in the rat hippocampus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Time course study of GFRalpha-1 expression in an animal model of stroke.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Compression alters kinase and phosphatase activity and tau and MAP2 phosphorylation transiently while inducing the fast adaptive dendritic remodeling of underlying cortical neurons.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of cytochrome P450 (CYP) 3A4 inhibitors on the anxiolytic action of tandospirone in rat contextual conditioned fear.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Beta-asarone attenuates ischemia-reperfusion-induced autophagy in rat brains via modulating JNK, p-JNK, Bcl-2 and Beclin 1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Proteomics of microparticles after experimental pulmonary embolism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Identification of a potent sodium hydrogen exchanger isoform 1 (NHE1) inhibitor with a suitable profile for chronic dosing and demonstrated cardioprotective effects in a preclinical model of myocardial infarction in the rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Angiotensin type 2 receptor actions contribute to angiotensin type 1 receptor blocker effects on kidney fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The role of alpha4 (CD49d) and beta2 (CD18) integrins in eosinophil and neutrophil migration to allergic lung inflammation in the Brown Norway rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Renal endothelin-converting enzyme in rats with congestive heart failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The antifibrotic effect of a serine protease inhibitor in the kidney.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Regulation of endothelin-converting enzyme 1 in nephrotic syndrome in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Proteomic analysis reveals the deregulation of inflammation-related proteins in acupuncture-treated rats with asthma onset.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased expression of calcium-sensing receptors in atherosclerosis confers hypersensitivity to acute myocardial infarction in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Early urinary and plasma biomarkers for experimental diabetic nephropathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Decrease in tumor necrosis factor-alpha receptor-associated death domain results from ubiquitin-dependent degradation in obstructive renal injury in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Placental growth factor contributes to micro-vascular abnormalization and blood-retinal barrier breakdown in diabetic retinopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Characterization of a rat model of Huntington's disease based on targeted expression of mutant huntingtin in the forebrain using adeno-associated viral vectors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dietary -linolenic acid-rich formula reduces adhesion molecules in rats with experimental colitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Renal prothrombin mRNA is significantly decreased in a hyperoxaluric rat model of nephrolithiasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Small interfering RNA targeting IKK prevents renal ischemia-reperfusion injury in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reductions in laminin beta2 mRNA translation are responsible for impaired IGFBP-5-mediated mesangial cell migration in the presence of high glucose.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Proteomic analysis of rat plasma following transient focal cerebral ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Angiotensin II receptor blockade improves matrix metalloproteinases/tissue inhibitor of matrix metalloproteinase-1 balance and restores fibronectin expression in rat infarcted myocardium.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Abundance of TRPC6 protein in glomerular mesangial cells is decreased by ROS and PKC in diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Curcumin and enalapril ameliorate renal failure by antagonizing inflammation in 5/6 nephrectomized rats: role of phospholipase and cyclooxygenase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Changes of gap junctional cell-cell communication in overactive detrusor in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Efficacy of a phosphorodiamidate morpholino oligomer antisense compound in the inhibition of corneal transplant rejection in a rat cornea transplant model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Curcumin attenuates diabetic nephropathy by inhibiting PKC- and PKC-1 activity in streptozotocin-induced type I diabetic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Connexins 40 and 43 are differentially regulated within the kidneys of rats with renovascular hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Subcutaneous injection containing IL-3 and GM-CSF ameliorates stab wound-induced brain injury in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Maternal high-fat intake during pregnancy programs metabolic-syndrome-related phenotypes through liver mitochondrial DNA copy number and transcriptional activity of liver PPARGC1A.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of medicinal extract for tonifying kidney to relieve asthma on glucocorticoid receptor expression in lung tissues of rats with bronchial asthma].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The Bone-Protective Effect of Genistein in the Animal Model of Bilateral Ovariectomy: Roles of Phytoestrogens and PTH/PTHR1 Against Post-Menopausal Osteoporosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Persistent accumulation of cyclooxygenase-1 (COX-1) expressing microglia/macrophages and upregulation by endothelium following spinal cord injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Acetyl-L-carnitine ameliorates mitochondrial dysfunction following contusion spinal cord injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of ginsenosides on hypothalamic-pituitary-adrenal function and brain-derived neurotrophic factor in rats exposed to chronic unpredictable mild stress].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Antagonism of alpha2A-adrenoceptor: a novel approach to inhibit inflammatory responses in sepsis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Glaucoma alters the expression of NGF and NGF receptors in visual cortex and geniculate nucleus of rats: effect of eye NGF application.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of hepatic nitric oxide synthases in rats with thioacetamide-induced acute liver failure and encephalopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Enhancement of endothelial nitric oxide synthase production reverses vascular dysfunction and inflammation in the hindlimbs of a rat model of diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Characterization of SV-40 Tag rats as a model to study prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Modified HMG-CoA reductase and LDLr regulation is deeply involved in age-related hypercholesterolemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Changes of encephalic contents of neuropeptides in rats with vascular dementia].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inhibition of 5-lipoxygenase-activating protein (FLAP) reduces pulmonary vascular reactivity and pulmonary hypertension in hypoxic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Influence of sesame oil on blood glucose, lipid peroxidation, and antioxidant status in streptozotocin diabetic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Total triterpene acids, active ingredients from Fructus Corni, attenuate diabetic cardiomyopathy by normalizing ET pathway and expression of FKBP12.6 and SERCA2a in streptozotocin-rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Kinin B1 and B2 receptor mRNA expression in the hypothalamus of spontaneously hypertensive rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Selective tumor blood-brain barrier opening with the kinin B2 receptor agonist [Phe(8)psi(CH(2)NH)Arg(9)]-BK in a F98 glioma rat model: an MRI study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Interleukin-1 beta induction of neuron apoptosis depends on p38 mitogen-activated protein kinase activity after spinal cord injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of endothelin receptor antagonist bosentan on chronic hypoxia-induced inflammation and chemoafferent neuron adaptation in rat carotid body.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Novel surrogate markers for acute brain damage: cerebrospinal fluid levels corrrelate with severity of ischemic neurodegeneration in the rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Endotoxin causes pulmonary hypertension by upregulating smooth muscle endothelin type-B receptors: role of aldose reductase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Molecular genetics of the SA-gene: cosegregation with hypertension and mapping to rat chromosome 1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Stimulation of expression of the intestinal glutamine transporter ATB0 in tumor-bearing rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inhibition of thromboxane synthesis attenuates insulin hypertension in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The role of expression of Toll-like receptor 2 and Toll-like receptor 4 in hyperoxia-induced acute lung injury in rat].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Evidence for the involvement of NADPH oxidase in ischemia/reperfusion-induced gastric damage via angiotensin II.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Toll-like receptor 4/nuclear factor-kappa B signaling detected in brain after early subarachnoid hemorrhage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Caveolin-3 was expressed constitutively in some astrocytes, but not in endothelial cells; its immunoreactivity was increased in reactive astrocytes in EAE lesions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Overexpression of messenger RNA for cholecystokinin-A receptor and novel expression of messenger RNA for gastrin (cholecystokinin-B) receptor in azaserine-induced rat pancreatic carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[These results indicate that silencing expression of CD36 can result in the inhibition of L-TGF-beta1 activation in a rat silicosis model, thus further preventing the development of silica-induced lung fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased levels of the CD40:CD40 ligand dyad in the cerebrospinal fluid of rats with vitamin B12(cobalamin)-deficient central neuropathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A rapid oxidation and persistent decrease in the vesicular monoamine transporter 2 after methamphetamine.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cross-species global and subset gene expression profiling identifies genes involved in prostate cancer response to selenium.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Retinoid X receptor alpha participation in dexamethasone-induced rat bile acid coenzyme A-amino acid N-acyltransferase expression in septic liver.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression of monocyte chemoattractant protein-1 in the cerebral artery after experimental subarachnoid hemorrhage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Grafts of adult subependymal zone neuronal progenitor cells rescue hemiparkinsonian behavioral decline.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pain-related anxiety-like behavior requires CRF1 receptors in the amygdala.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of TIMP-1 and TIMP-2 in the progression of cerebral aneurysms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Efficacy of new retinoids in the prevention of mammary cancers and correlations with short-term biomarkers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Vascular effects of a common gene variant of extracellular superoxide dismutase in heart failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The roles of interleukin-5 and eotaxin in signal transmission between lung and bone marrow of rat asthmatic models].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CD36 deficiency leads to choroidal involution via COX2 down-regulation in rodents.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of cannabinoid receptors in regulation of cardiac tolerance to ischemia and reperfusion].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Type 1 diabetes alters brain cannabinoid receptor expression and phosphorylation status in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inhibitory effects of astragaloside IV on diabetic peripheral neuropathy in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Beneficial effects of modified egg* on oxidative stress in F1- generation of metabolic syndrome-X induced Wistar rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In vivo modulation of annexins I, II and V expression by thyroxine and methylthiouracil.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inflammatory neutrophils secrete annexin 1 during experimentally induced colitis in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression of phospholipase D isozymes in scar and viable tissue in congestive heart failure due to myocardial infarction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Differential expression of phospholipase D isozymes in the hippocampus following kainic acid-induced seizures.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Muscle amino acid pattern in obese rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The roles of interleukin-18 in collagen-induced arthritis in the BB rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Despite similar reduction of blood pressure and renal ANG II and ET-1 levels aliskiren but not losartan normalizes albuminuria in hypertensive Ren-2 rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Alterations in protein kinase C isoenzyme expression and autophosphorylation during the progression of pressure overload-induced left ventricular hypertrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inhibiting epidermal growth factor receptor attenuates reactive astrogliosis and improves functional outcome after spinal cord injury in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The activity of ornithine transcarbamoylase and arginase during mechanical jaundice in the rat model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hypertension and exercise training differentially affect oxytocin and oxytocin receptor expression in the brain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Endothelial sulfonylurea receptor 1-regulated NC Ca-ATP channels mediate progressive hemorrhagic necrosis following spinal cord injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Upregulation of Dpysl2 and Spna2 gene expression in the rat brain after ischemic stroke.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of vitamin B6 deficiency on the synthesis and accumulation of S-adenosylhomocysteine and S-adenosylmethionine in rat tissues.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The effect of cdk-5 overexpression on tau phosphorylation and spatial memory of rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[PACAP-mediated ATP release from rat urothelium and regulation of PACAP/VIP and receptor mRNA in micturition pathways after cyclophosphamide (CYP)-induced cystitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Epigallocatechin-3-gallate attenuates cardiac hypertrophy in hypertensive rats in part by modulation of mitogen-activated protein kinase signals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cholecystokinin octapeptide improves cardiac function by activating cholecystokinin octapeptide receptor in endotoxic shock rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Overexpression of genes in the CA1 hippocampus region of adult rat following episodes of global ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Specific allelic loss of p16 (INK4A) tumor suppressor gene after weeks of iron-mediated oxidative damage during rat renal carcinogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[It was concluded that the expression of IL-17 was increased significantly in asthmatic rats and could be inhibited partly by dexamethasone, suggesting that IL-17 might play an important role in the pathogenesis of asthma as an inflammation regulation factor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression of smooth muscle MyHC B in blood vessels of hypertrophied heart in experimentally hypertensive rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Altered expression of immune modulator and structural genes in neonatal unilateral ureteral obstruction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[In vivo effect of Trigonella foenum graecum on the expression of pyruvate kinase, phosphoenolpyruvate carboxykinase, and distribution of glucose transporter (GLUT4) in alloxan-diabetic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[C-reactive protein and natural IgM antibodies are activators of complement in a rat model of intestinal ischemia and reperfusion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of caspases on cell death, inflammation, and cell cycle in glycerol-induced acute renal failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of kidney ADP-ribosyl cyclase in diabetic nephropathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Frequent mutation of p16(CDKN2A) exon 1 during rat tongue carcinogenesis induced by 4-nitroquinoline-1-oxide.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Influence of blood glucose on the expression of glucose trans-porter proteins 1 and 3 in the brain of diabetic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Early modifications in N-methyl-D-aspartate receptor subunit mRNA levels in an oxygen and glucose deprivation model using rat hippocampal brain slices.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Delayed, but prolonged increases in astrocytic clusterin (ApoJ) mRNA expression following acute cortical spreading depression in the rat: evidence for a role of clusterin in ischemic tolerance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Aldose reductase inhibitor zopolrestat restores allergic hyporesponsiveness in alloxan-diabetic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Among them, overexpression of annexin a1 (ANNA1) in rat TCCs was confirmed by Western blotting and real-time RT-PCR analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role for IkappaBalpha, but not c-Rel, in skeletal muscle atrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Systemic and intrathecal effects of a novel series of phospholipase A2 inhibitors on hyperalgesia and spinal prostaglandin E2 release.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Upregulation of intracardiac adrenomedullin and its receptor system in rats with volume overload-induced cardiac hypertrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Protein kinase C-delta mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Additive inhibitory effect of experimentally induced hepatic cirrhosis by agonists of peroxisome proliferator activator receptor gamma and retinoic acid receptor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[N-acetylcysteine attenuates PKCbeta2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Skin-derived precursors differentiating into dopaminergic neuronal cells in the brains of Parkinson disease model rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Coexistence of hypercholesterolemia and hypertension impairs adventitial vascularization.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Propofol reduces nitric oxide-induced apoptosis in testicular ischemia-reperfusion injury by downregulating the expression of inducible nitric oxide synthase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of neonatal nutrition on the enzyme activity of liver lysosomes, adipocytes and thrombocytes in young and old rats].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Experimental autoimmune neuritis induces differential microglia activation in the rat spinal cord.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inhibition of LTB4 biosynthesis in situ by CGS 23885, a potent 5-lipoxygenase inhibitor, correlates with its pleural fluid concentrations in an experimentally induced rat pleurisy model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Rats fed on a monounsaturated fat-rich diet do not develop hypothalamic leptin resistance, whereas toll-like receptor 4 loss-of-function mutation and immunopharmacological inhibition of toll-like receptor 4 protects mice from diet-induced obesity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Macrophages and neurons are targets of retinoic acid signaling after spinal cord contusion injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hydrolase activities in the rat aorta. II. Effects of hypertension alone and in combination with diabetes mellitus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The effects of aerosolized STAT1 antisense oligodeoxynucleotides on rat pulmonary fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Infection of rats with Taenia taeniformis metacestodes increases hepatic CYP450, induces the activity of CYP1A1, CYP2B1 and COH isoforms and increases the genotoxicity of the procarcinogens benzo[a]pyrene, cyclophosphamide and aflatoxin B(1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Uteroplacental insufficiency alters nephrogenesis and downregulates cyclooxygenase-2 expression in a model of IUGR with adult-onset hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Major role for hypoxia inducible factor-1 and the endothelin system in promoting myocardial infarction and hypertension in an animal model of obstructive sleep apnea.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Transcriptomic and innate immune responses to Yersinia pestis in the lymph node during bubonic plague.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Renal endothelin gene expression is increased in remnant kidney and correlates with disease progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Rosiglitazone, a PPAR gamma agonist: potent promoter of hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Enzyme-linked immunosorbent assay of carbamoylphosphate synthetase I: plasma enzyme in rat experimental hepatitis and its clearance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The effect of caffeic acid phenethyl ester on short-term acute myocardial ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Insulin induces expression of adenosine kinase gene in rat lymphocytes by signaling through the mitogen-activated protein kinase pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Regulation of protein kinase C isozymes in volume overload cardiac hypertrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The protective effect of Salvia miltiorrhiza in an animal model of early experimentally induced diabetic nephropathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Nicorandil protects against lethal ischemic ventricular arrhythmias and up-regulates endothelial nitric oxide synthase expression and sulfonylurea receptor 2 mRNA in conscious rats with acute myocardial infarction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Adenosine deaminase activity in serum, erythrocytes and lymphocytes of rats infected with Leptospira icterohaemorrhagiae.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Differential regulation of CXCL12 and PACAP mRNA expression after focal and global ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Stimulation of the lateral hypothalamus produces antinociception mediated by 5-HT1A, 5-HT1B and 5-HT3 receptors in the rat spinal cord dorsal horn.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Programmed upregulation of adipogenic transcription factors in intrauterine growth-restricted offspring.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Experimental hypothyroidism inhibits delta-aminolevulinate dehydratase activity in neonatal rat blood and liver.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Treatment with mycophenolate mofetil attenuates the development of Heymann nephritis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Black tea prevents high fat diet-induced non-alcoholic steatohepatitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[C6 mediates chronic progression of tubulointerstitial damage in rats with remnant kidneys.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hyperhomocysteinemia associated with decreased renal transsulfuration activity in Dahl S rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Analysis of the glucose transporter compliment of metabolically important tissues from the Milan hypertensive rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Dexfenfluramine-associated changes in 5-hydroxytryptamine transporter expression and development of hypoxic pulmonary hypertension in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Liver injury following renal ischemia reperfusion in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[C/EBP DNA-binding activity is upregulated by a glucocorticoid-dependent mechanism in septic muscle.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Beneficial effects of Vitis coignetiae Pulliat leaves on nonalcoholic steatohepatitis in a rat model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Soluble TGFbeta type II receptor gene therapy ameliorates acute radiation-induced pulmonary injury in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Upregulation of angiotensin-converting enzyme (ACE) 2 in hepatic fibrosis by ACE inhibitors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A nuclear factor-kappaB inhibitor pyrrolidine dithiocarbamate ameliorates pulmonary hypertension in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Protective effect of Chinese prescription Kangen-karyu and its crude drug Tanjin against age-related lipidosis in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of c-Jun N-terminal kinase in early brain injury after subarachnoid hemorrhage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression and roles of CDK4 and p21 in lung tissues of premature rats with hyperoxia-induced chronic lung disease].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Up-regulation of macrophage colony-stimulating factor (M-CSF) and migration inhibitory factor (MIF) expression and monocyte recruitment during lipid-induced glomerular injury in the exogenous hypercholesterolaemic (ExHC) rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression profiling in skeletal muscle of Zucker diabetic fatty rats: implications for a role of stearoyl-CoA desaturase 1 in insulin resistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Involvement of CD40-CD40L signaling in postischemic lung injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Adaptive immune response in osteoclastic bone resorption induced by orally administered Aggregatibacter actinomycetemcomitans in a rat model of periodontal disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CCR3- and CXCR4-mediated interactions regulate migration of CD34+ human bone marrow progenitors to ischemic myocardium and subsequent tissue repair.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Chronic exposure to ammonia induces isoform-selective alterations in the intracellular distribution and NMDA receptor-mediated translocation of protein kinase C in cerebellar neurons in culture.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[mRNA levels of the hypoxia inducible factor (HIF-1) and DNA repair genes in perinatal asphyxia of the rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Phospholipid alterations in hepatocyte membranes and transporter protein changes in cholestatic rat model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Efficacy of grape seed proanthocyanidins on cardioprotection during isoproterenol-induced myocardial injury in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Irsogladine maleate regulates neutrophil migration and E-cadherin expression in gingival epithelium stimulated by Aggregatibacter actinomycetemcomitans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Akt pathway is required for oestrogen-mediated attenuation of lung injury in a rodent model of cerulein-induced acute pancreatitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Downregulation of the expression of bone morphogenetic protein 7 in experimental pyelonephritis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The effects of treatment with antibodies to transforming growth factor beta1 and beta2 following spinal cord damage in the adult rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The anti-inflammatory effect of celecoxib does not prevent liver fibrosis in bile duct-ligated rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Activities of enzymes involved in the metabolism of ether-linked lipids in normal and neoplastic tissues of rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Activation of Toll-like receptors 2 and 4 in Aspergillus fumigatus keratitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reduced albumin reabsorption in the proximal tubule of early-stage diabetic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Angiopoietin 1 and 2 gene and protein expression is differentially regulated in acute anti-Thy1.1 glomerulonephritis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Distribution of bone morphogenetic protein and bone morphogenetic protein receptor transcripts in the rodent nervous system and up-regulation of bone morphogenetic protein receptor type II in hippocampal dentate gyrus in a rat model of global cerebral ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Tissue factor pathway inhibitor and thrombin activatable fibrinolytic inhibitor plasma levels following burn and septic injuries in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Bevacizumab and rapamycin inhibit tumor growth in peritoneal model of human ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gonadal hormones and frontocortical expression of vascular endothelial growth factor in male stroke-prone, spontaneously hypertensive rats, a model for attention-deficit/hyperactivity disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Leptin treatment confers clinical benefit at multiple stages of virally induced type 1 diabetes in BB rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Antitumor activity of endostatin against carcinogen-induced rat primary mammary tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[ICA69(null) nonobese diabetic mice develop diabetes, but resist disease acceleration by cyclophosphamide.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Therapeutic efficacy of intranasally delivered mesenchymal stem cells in a rat model of Parkinson disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin-induced lung injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression profiling distinguishes between spontaneous and radiation-induced rat mammary carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Upregulation of EphA2 during in vivo and in vitro renal ischemia-reperfusion injury: role of Src kinases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Stimulation of intestinal glutamine absorption in chronic metabolic acidosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[L-citrulline attenuates arrested alveolar growth and pulmonary hypertension in oxygen-induced lung injury in newborn rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Protective effect of the V1a receptor antagonist SR49059 on brain edema formation following middle cerebral artery occlusion in the rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Detection of ClC-3 and ClC-5 in epididymal epithelium: immunofluorescence and RT-PCR after LCM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Changes of skeletal muscle adiponectin content in diet-induced insulin resistant rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[MMP/TIMP expression in spontaneously hypertensive heart failure rats: the effect of ACE- and MMP-inhibition.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Mapping of A gene responsible for cataract formation and its modifier in the UPL rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Age and meloxicam attenuate the ischemia/reperfusion-induced down-regulation in the NMDA receptor genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Fractalkine, a novel chemokine in rheumatoid arthritis and in rat adjuvant-induced arthritis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Differential expression of apoptosis-associated genes post-hepatectomy in cirrhotic vs. normal rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Coordinate Notch3-hairy-related transcription factor pathway regulation in response to arterial injury. Mediator role of platelet-derived growth factor and ERK.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: prevention by lipoic acid treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[STAT1 antisense oligonucleotides inhibit secretion of TNF-alpha, IL-8 and NO in alveolar macrophages of rats suffering from interstitial pulmonary fibrosis].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Ischemia-reperfusion injury activates innate immunity in rat kidneys.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Beneficial effects of TLR-2/6 ligation in pulmonary bacterial infection and immunization with Pseudomonas aeruginosa.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Arterial gene transfer of the TGF-beta signalling protein Smad3 induces adaptive remodelling following angioplasty: a role for CTGF.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Protective effect of total aralosides of Aralia elata (Miq) Seem (TASAES) against diabetic cardiomyopathy in rats during the early stage, and possible mechanisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Intraventricular injection of antibodies to beta1-integrins generates pressure gradients in the brain favoring hydrocephalus development in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Reduced expression level of mgmt mRNA and beta-catenin gene mutation in rat colon tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[BTEB2, a Krppel-like transcription factor, regulates expression of the SMemb/Nonmuscle myosin heavy chain B (SMemb/NMHC-B) gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Potential role of JAK/STAT in regulating Toll-like receptor 2 gene expression in rats with postburn Staphylococcus aureus sepsis].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Regulation of cardiomyocyte hypertrophy in diabetes at the transcriptional level.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Two-dimensional electrophoresis protein profiling and identification in rat bronchoalveolar lavage fluid following allergen and endotoxin challenge.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Correlation of repressed transcription of alpha-tocopherol transfer protein with serum alpha-tocopherol during hepatocarcinogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Prevention of free fatty acid-induced hepatic lipotoxicity by 18beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression of fractalkine and fractalkine receptor in urinary bladder after cyclophosphamide (CYP)-induced cystitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Activation of NADPH oxidase and extracellular superoxide production in seizure-induced hippocampal damage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Identification of the mouse and rat orthologs of the gene mutated in Usher syndrome type IIA and the cellular source of USH2A mRNA in retina, a target tissue of the disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The induction of cell cycle regulatory and DNA repair proteins in cisplatin-induced acute renal failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Continuous delta-opioid receptor activation reduces neuronal voltage-gated sodium channel (NaV1.7) levels through activation of protein kinase C in painful diabetic neuropathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Force-dependent development of neuropathic central pain and time-related CCL2/CCR2 expression after graded spinal cord contusion injuries of the rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Antisense oligonucleotides against the lipid phosphatase SHIP2 improve muscle insulin sensitivity in a dietary rat model of the metabolic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Neuroprotective effect of the peptides ADNF-9 and NAP on hypoxic-ischemic brain injury in neonatal rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[A novel member of the transmembrane serine/threonine kinase receptor family is specifically expressed in the gonads and in mesenchymal cells adjacent to the mllerian duct.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Study of impaired metabolism of guanidinoacetic acid in uremia--the compensatory role of the pancreas in guanidinoacetic acid synthesis].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Intrathecal injection of anti-CX3CR1 neutralizing antibody delayed and attenuated pain facilitation in rat tibial bone cancer pain model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[c-Src-dependent nongenomic signaling responses to aldosterone are increased in vascular myocytes from spontaneously hypertensive rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[L-DOPA treatment of parkinsonian rats changes the expression of Src, Lyn and PKC kinases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[NKCC1 transporter facilitates seizures in the developing brain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inhibition of Na(+)-K(+)-Cl(-) cotransporter during focal cerebral ischemia decreases edema and neuronal damage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Morin regulates the expression of NF-kappaB-p65, COX-2 and matrix metalloproteinases in diethylnitrosamine induced rat hepatocellular carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of glycosaminoglycans on matrix metalloproteinases in type II collagen-induced experimental arthritis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Identification and characterization of a gene regulating enzymatic glycosylation which is induced by diabetes and hyperglycemia specifically in rat cardiac tissue.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[XLF-III-43, a novel coumarin-aspirin compound, prevents diabetic nephropathy in rats via inhibiting advanced glycation end products.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Ameliorative effect of berberine on endothelial dysfunction in diabetic rats induced by high-fat diet and streptozotocin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Factor VII transcription correlates with hepatocyte proliferation and hepatocyte growth factor expression in a rodent extrahepatic portal vein obstruction model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression of MRP2 and MRP3 during liver regeneration after 90% partial hepatectomy in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Involvement of macrophage migration inhibitory factor (MIF) in experimental uric acid nephropathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Uncaria rhynchophylla upregulates the expression of MIF and cyclophilin A in kainic acid-induced epilepsy rats: A proteomic analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression profiles of major cytokines in the nucleus tractus solitarii of the spontaneously hypertensive rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[L-arginine attenuates APE-induced pulmonary hypertension through mechanisms involving increased NO synthesis and maybe attenuation of lung MMP-2 and MMP-9 activities.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Modulation of extracellular matrix components by metalloproteinases and their tissue inhibitors during degeneration and regeneration of rat sural nerve.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Highly purified eicosapentaenoic acid ethyl ester prevents development of steatosis and hepatic fibrosis in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Role of connective tissue growth factor in experimental radiation nephropathy in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The involvement of NF-kappaB p65/p52 in the effects of GDNF on DA neurons in early PD rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Moxibustion treatment restoring the intestinal epithelium barrier in rats with Crohn's disease by down-regulating tumor necrosis factor alpha, tumor necrosis factor receptor 1, and tumor necrosis factor receptor 2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-1 pathways in cardiac fibroblasts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Health effects of subchronic exposure to environmental levels of diesel exhaust.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The content of glycogen phosphorylase and glycogen in preparations of sarcoplasmic reticulum-glycogenolytic complex is enhanced in diabetic rat skeletal muscle.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Minocycline modulates chemokine receptors but not interleukin-10 mRNA expression in hypoxic-ischemic neonatal rat brain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The protective effects of interleukin-18 and interferon- on neuronal damages in the rat hippocampus following status epilepticus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Chronic aspiration of gastric fluid induces the development of obliterative bronchiolitis in rat lung transplants.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effect of garlicin on the serum levels of interleukin 4 and interferon gamma in allergic rhinitis model in rats].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Comparative changes in the blood-brain barrier and cerebral infarction of SHR and WKY rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Nuclear factor-kappa B regulates seizure threshold and gene transcription following convulsant stimulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Changes in rat liver cytochromes b, c1, and c and mitochondrial protein in prolonged protein deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Proliferation and differentiation of neural stem cells in adult rats after cerebral infarction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Proteomic analysis of rat retina in a steroid-induced ocular hypertension model: potential vulnerability to oxidative stress.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Inhaled iloprost reverses vascular remodeling in chronic experimental pulmonary hypertension.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Differential gene signatures in rat mammary tumors induced by DMBA and those induced by fractionated gamma radiation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[The protective effect of dexanabinol (HU-211) on nitric oxide and cysteine protease-mediated neuronal death in focal cerebral ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Interactions of chemokines and chemokine receptors mediate the migration of mesenchymal stem cells to the impaired site in the brain after hypoglossal nerve injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pituitary and hypothalamic somatostatin receptor subtype messenger ribonucleic acid expression in the food-deprived and diabetic rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Disruption in the expression and immunolocalisation of steroid receptors and steroidogenic enzymes in letrozole-induced polycystic ovaries in rat.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Serum levels of matrix metalloproteinase-2 as a marker of intimal hyperplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Expression of concentrative nucleoside transporters SLC28 (CNT1, CNT2, and CNT3) along the rat nephron: effect of diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Effects of TX0201 abstracted from heart-regulating formula on spatial learning and regulation of Bax mRNA, Bcl-2 mRNA level in brain of rat with Alzheimer's disease].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[CD2AP expression in a renal ischemia/reperfusion injury model and analysis of its related genes using overexpression and RNA interference technique.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Pyrexia, anorexia, adipsia, and depressed motor activity in rats during systemic inflammation induced by the Toll-like receptors-2 and -6 agonists MALP-2 and FSL-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Temporal changes in gene expression after injury in the rat retina.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Hyperglycemia in streptozotocin-induced diabetic rat increases infarct size associated with low levels of myocardial HO-1 during ischemia/reperfusion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Antioxidant role of heme oxygenase-1 in prehepatic portal hypertensive rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Disparate regulation of signaling proteins after exercise and myocardial infarction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Neuregulin in cardiac hypertrophy in rats with aortic stenosis. Differential expression of erbB2 and erbB4 receptors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Gene expression of hormone sensitive lipase and lipoprotein lipase in obesity-prone and obesity-resistant rats induced by high-fat diet].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.

[Soy protein reduces hepatic lipotoxicity in hyperinsulinemic obese Zucker fa/fa rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Inhibition of colon carcinogenesis by post-initiation induction of NQO1 in Sprague-Dawley rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcers via EP4 receptors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Preliminary investigation of the changes and mechanism of Leptin after myocardial ischemia/reperfusion injury].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The effects of alcohol on rat placenta.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Changes in intestinal Toll-like receptors and cytokines precede histological injury in a rat model of necrotizing enterocolitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Silencing of Cited2 and Akap12 genes in radiation-induced rat osteosarcomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Intravesical immune suppression by liposomal tacrolimus in cyclophosphamide-induced inflammatory cystitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Effect of decompressive craniectomy on aquaporin-4 expression after lateral fluid percussion injury in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Evidence that elevated plasma corticosterone levels are the cause of reduced hypothalamic corticotrophin-releasing hormone gene expression in diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Celecoxib, a selective cyclooxygenase-2 inhibitor, attenuates renal injury in a rat model of Cisplatin-induced nephrotoxicity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Pulpar tooth injury induces plastic changes in S100B positive astroglial cells in the trigeminal subnucleus caudalis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Intermittent hypoxia during sleep induces reactive gliosis and limited neuronal death in rats: implications for sleep apnea.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The effect of tamoxifen on bladder functions and histology, and the role of estrogen receptor beta in a rat chemical cystitis model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The expression change of -arrestins in fibroblast-like synoviocytes from rats with collagen-induced arthritis and the effect of total glucosides of paeony.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Dexamethasone pre-treatment protects brain against hypoxic-ischemic injury partially through up-regulation of vascular endothelial growth factor A in neonatal rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Acetate supplementation reduces microglia activation and brain interleukin-1 levels in a rat model of Lyme neuroborreliosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Intermittent noxious stimulation following spinal cord contusion injury impairs locomotor recovery and reduces spinal brain-derived neurotrophic factor-tropomyosin-receptor kinase signaling in adult rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Structural equation modeling highlights the potential of Kim-1 as a biomarker for chronic kidney disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Delay of LPS-induced acute lung injury resolution by soluble immune complexes is neutrophil dependent.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[GDNF, Ret, GFRalpha1 and 2 in the adult rat retino-tectal system after optic nerve transection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Regulation of synthesis and oxidation of fatty acids by adiponectin receptors (AdipoR1/R2) and insulin receptor substrate isoforms (IRS-1/-2) of the liver in a nonalcoholic steatohepatitis animal model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[In situ hybridization of mRNA expression for IP3 receptor and IP3-3-kinase in rat brain after transient focal cerebral ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Effects of Kupffer cell blockade on the hepatic expression of metallothionein and heme oxygenase genes in endotoxemic rats with obstructive jaundice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The role and mechanism of the up-regulation of fibrinolytic activity in painful peripheral nerve injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Hepatic stimulator substance alleviates toxin-induced and immune-mediated liver injury and fibrosis in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Apocynin attenuates lipopolysaccharide-induced lung injury in an isolated and perfused rat lung model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Passive transfer of experimental autoimmune encephalomyelitis in Wistar rats: dissociation of clinical symptoms and biochemical alterations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Protective effects of Polygonatum sibiricum polysaccharide on ovariectomy-induced bone loss in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Up-regulation of splenic prohormone convertases PC1 and PC2 in diabetic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[uPA, uPAR and TGF expression during early and late post myocardial infarction period in rat myocardium.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Expression of antioxidant molecules after peripheral nerve injury and regeneration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Deleterious effects of plasminogen activators in neonatal cerebral hypoxia-ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Shortening and intracellular Ca2+ in ventricular myocytes and expression of genes encoding cardiac muscle proteins in early onset type 2 diabetic Goto-Kakizaki rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Leptin resistance and desensitization of hypophagia during prolonged inflammatory challenge.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Expression of glutamine synthetase and glutamate dehydrogenase in the latent phase and chronic phase in the kainate model of temporal lobe epilepsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Expression of the dopaminergic D1 and D2 receptors in the anterior cingulate cortex in a model of neuropathic pain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Decrease in calcium-sensing receptor in the progress of diabetic cardiomyopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Proteomic identification of biomarkers of vascular injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Maternal hypoxia alters matrix metalloproteinase expression patterns and causes cardiac remodeling in fetal and neonatal rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Cerebrovascular connexin expression: effects of traumatic brain injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Retinoid receptor-specific agonists alleviate experimental glomerulonephritis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Evaluation of the Effect of Different Doses of Low Energy Shock Wave Therapy on the Erectile Function of Streptozotocin (STZ)-Induced Diabetic Rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Advanced glycation end products (AGE) induce the receptor for AGE in the colonic mucosa of azoxymethane-injected Fischer 344 rats fed with a high-linoleic acid and high-glucose diet.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Tissue expression of TRPC3 and TRPC6 in hypertensive Munich Wistar Frmter rats showing proteinuria.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Stem cell factor attenuates liver damage in a murine model of acetaminophen-induced hepatic injury.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[A new ENU-induced allele of mouse quaking causes severe CNS dysmyelination.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[This study implies a genetic predisposition to sarcoidosis in the Turkish population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
Gene-disease associations inferred from text-mining the literature.
DisGeNET evidence - LITERATURE
[Ethnic and geographical differences in HLA associations with the outcome of hepatitis C virus infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Human leukocyte antigen class I genotypes in relation to heterosexual HIV type 1 transmission within discordant couples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[HLA-associated clinical progression correlates with epitope reversion rates in early human immunodeficiency virus infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Hereditary HFE Hemochromatosis is an inherited disorder of iron metabolism that results from mutations in the HFE gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Association between HFE 187 C>G (H63D) mutation and early-onset familial Alzheimer's disease PSEN-1 839A>C (E280A) mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Hemochromatosis (HFE) and transferrin receptor-1 (TFRC1) genes in sporadic porphyria cutanea tarda (sPCT).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Hemochromatosis gene sequence deviations in German patients with porphyria cutanea tarda.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Increased prevalence of the HFE C282Y hemochromatosis allele in women with breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We describe for the first time a homozygous HFE splice site mutation (IVS5 G/A) in a non-Caucasian patient with hereditary hemochromatosis. Although the absence of this novel HFE gene mutation in Caucasian subjects suggests that the mutation is exclusive to this family, mutation screening in populations of different ethnic background is recommended to precisely define its contribution to hereditary hemochromatosis in non-Caucasian patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Risk of venous thromboembolism associated with the common hereditary haemochromatosis Hfe gene (C282Y) mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Juvenile hemochromatosis (JH) is a characteristic form of genetic hemochromatosis with an early onset and severe clinical course leading to death if iron depletion treatment is not timely applied.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The data suggest that the HCRTR2 gene or a linked locus significantly modulates the risk for cluster headache.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Screening of concurrent alpha-thalassaemia 1 in beta-thalassaemia carriers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Genotype-phenotype correlation was established.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Sickle hemoglobin (HbS) allele and sickle cell disease: a HuGE review.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We observed three alleles, A (AC)16, B (AC)14, and C (AC)18, with a frequency of between 68.2% and 86.9%, 13.1% and 18.2%, and 6.7% and 13.7%, respectively. Allele C was present only in Purepecha and Mestizo groups.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[In conclusion, the M416V polymorphism of GYS1 gene is not associated with insulin resistance in type 2 diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ The results suggest that the Xbal polymorphism of the glycogen synthase gene could not be used as a genetic marker for NIDDM in Chinese population of Henan Han nationality.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We conducted a hospital-based case-control study including 727 cases and 736 healthy controls to evaluate the associations of the polymorphic phase-I and -II biotransformations (CYP1A1, CYP1A2, GSTM1, GSTT1, GSTP1, NAT1 and NAT2) and DNA-repair enzymes (XRCC1, XRCC3 and XPD) with the risk of contracting colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[In addition, the frequencies of the GSTM1 and GSTT1 deletion genotypes differed significantly between the cases and controls for current smokers; the GSTT1 null genotype especially is associated with a greater risk of colorectal cancer (OR = 2.44, 95% CI: 1.24-4.81).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Protein carbonyl levels, glutathione S-transferase polymorphisms and risk of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The distribution of GSTM1 and GSTT1 polymorphisms was not significantly different between LC patients and the controls, suggesting that GSTM1 and GSTT1 alone or in combination are not independent risk factors for LC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and neck cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Glutathione S-transferase M1, T1 status and the risk of head and neck cancer: a meta-analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The genetic polymorphisms of biotransformation phase I enzymes, cytochrome P450 (CYP1A1 and CYP2D6), and phase II enzymes, glutathione S-transferase (GSTM1 and GSTT1), were analyzed in 204 healthy persons and 348 leukemia patients, who suffered from also acute lymphoblastic leukemia (ALL), acute nonlymphoblastic leukemia (ANLL) chronic myelogenous leukemia (CML), from the Han ethnic group in Changsha City of Hunan Province of China.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Glutathione-S-transferase genotypes, smoking, and their association with markers of inflammation, hemostasis, and endothelial function: the atherosclerosis risk in communities (ARIC) study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ Further study of the role of the AhR polymorphism is warranted.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The highest frequency of individuals with the null genotype of both genes was observed in the Kalmyk and Buryat populations. The results may be used to study the effect of climatic and ecological conditions on multifactorial disease incidence in populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Genetic polymorphisms of GSTP1 related to response to 5-FU-oxaliplatin-based chemotherapy and clinical outcome in advanced colorectal cancer patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: the FOCUS trial.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The estimated lung cancer risk for GSTM1 null, GSTP1 Ile/Val and GSTP1 Val/Val combined genotype was 1.44 (95% CI: 0.73-2.83), suggesting the absence of modifying effect of defective GSTM1 and GSTP1 alleles on lung cancer predisposition.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Understanding the contribution of GST gene polymorphisms and their interactions with other relevant factors may improve screening diagnostic assays for prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Maternal and fetal single nucleotide polymorphisms in the epoxide hydrolase and gluthatione S-transferase P1 genes are not associated with pre-eclampsia in the Coloured population of the Western Cape, South Africa.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Except for nationality, patients with ALD in this series tended to have a higher mRNA expression of CYPIIE1 and to carry the C2 allele, and tended to have a lower mRNA expression of GSTP1 and to carry the Val allele.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[A study was undertaken to investigate associations of variants in EPHX1, GSTM1, GSTP1 and GSTT1 with asthma and the relationships between asthma, EPHX1 metabolic phenotypes and exposure to sources of PAHs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We conclude from our data that polymorphisms within GSTP1 do not play a major role in the development of bronchial asthma in German children.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[No differences for GSTM1 and GSTP1 genotype prevalence between the bladder cancer cases and the controls were observed, however, the null genotype for the GSTT1 gene and the A/G and G/G variants of the CYP1A1 gene may contribute to the development of bladder cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[GSTP1 AG or GG genotype has a higher frequency in the patients with benzidine related occupational bladder cancer, and further work is needed to confirm if GSTP1 AG or GG genotype plays a role in the development of occupational bladder cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[These results suggest that the GSTT1 null genotype may be associated with increased risk of stomach cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[There was a significant difference in GSTP1 allele gene distribution between the area of high incidence of gastric cancer(23%) and low incidence(20%).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Influence of glutathione S-transferase polymorphisms on genotoxic effects induced by tobacco smoke.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Overall, glutathione-S-transferase M1 conferred a significant increase in risk of solar keratoses development, particularly in the presence of high outdoor exposure and synergistically with known phenotypic risk factors of fair skin and inability to tan.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ The GSTO1 and GSTO2 genes flanked by the investigated polymorphisms are not comprised in a primary candidate region influencing AO in HD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Additional markers in these genes need to be screened to explore their role in the etiology of AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Genetic susceptibility to distinct bladder cancer subphenotypes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Susceptibility genes: GSTM1 and GSTM3 as genetic risk factors in bladder cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The knowledge of GSTM1 variant status seems to be potentially useful to predict a possible hypertensive status after 80 years of age.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Genetic polymorphism in patients with colorectal and with head and neck cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[CYP1A1 heterozygous mutation and homozygous mutation gene combined with GSTT1 null genotypes in mothers could increase the risk of preterm delivery.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Women withthe simultaneous occurrence of two or more genetic polymorphisms in the above-mentioned biotransformation enzymes, most probably resulting in a disturbed detoxification capacity, may be at increased risk for pre-eclampsia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[After correction for this bias, there is no evidence that women with GSTM1 null genotype have increased risk of developing endometriosis as compared with women with other genotypes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Polymorphisms of CYP1A1, GSTM1, GSTT1, and prostate cancer risk in Turkish population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[In this report, genetic polymorphism of phase I and II metabolic enzyme (CYP2E1, CYP17, GSTM1 and GSTT1) genes, living habits, and risk of prostate cancer (PCa) was studied in 163 patients with prostate carcinoma of Han nationality in Southern China and 202 age-matched controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Polymorphism of the genes for antioxidant defense enzymes and their association with the development of chronic obstructive pulmonary disease in the population of Bashkortostan.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Oxidative damage to biological macromolecules in Prague bus drivers and garagemen: impact of air pollution and genetic polymorphisms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Influence of genetic polymorphisms in CYP3A4, CYP3A5, GSTP1, GSTM1, GSTT1 and MDR1 genes on survival and therapy-related toxicity in multiple myeloma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[However, null types of GSTM1 and GSTT1 polymorphisms were not associated with the MM risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Genetic polymorphisms of GSTT1, GSTM1, GSTP1, MnSOD, and catalase in nonhereditary chronic pancreatitis: evidence of xenobiotic stress and impaired antioxidant capacity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Relationship between GSTT1, GSTM1 and NQO1 gene polymorphism and acute myeloid leukemia and recurrent chromosome translocations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[GST polymorphisms, interaction with smoking and pesticide use, and risk for Parkinson's disease in a Japanese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Combination of TNF-RII, CYP1A1 and GSTM1 polymorphisms and the risk of Japanese SLE: findings from the KYSS study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[In a retrospective study, we investigated associations between common polymorphisms in genes for several GST subclasses (GSTP1, GSTT1, GSTM1) and survival of patients with metastatic colorectal cancer receiving 5-fluorouracil (5-FU)/oxaliplatin chemotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Thus, individuals who are homozygous hGSTA1(*)B, and who would be predicted to have the lowest levels of hGSTA1 expression in their livers, appear to be at risk of developing CRC, possibly as a result of inefficient hepatic detoxification of N-acetoxy-PhIP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Using a prostate cancer case-control population, it was found that GSTA1*A/GSTA2 C335 and GSTA1*B/GSTA2 G335 were in linkage disequilibrium in Caucasians but not in African-Americans. However, there were no significant differences in the distribution of these polymorphisms or resultant haplotypes by case status. nevertheless, the rare genotypes, GSTA2*E/*E and GSTA1*B/*B + GSTA2*C/*C (potential low GSTA2 activity and low hepatic GSTA1 and GSTA2 expression, respectively) could increase the risk of adverse effects of xenobiotics via compromised efficiency of detoxification.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The metabotropic glutamate receptor 8 gene at 7q31: partial duplication and possible association with autism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Genetic analysis of a functional GRIN2A promoter (GT)n repeat in bipolar disorder pedigrees in humans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The association reported in this study suggests that the GRIN1 gene is a good candidate for the susceptibility to schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[These results suggest that the five SNPs within the GRIK4 gene are unlikely to play a major role in the susceptibility to schizophrenia in the Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Family-based association study between GRIK2 polymorphisms and autism spectrum disorders in the Korean trios.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Linkage and candidate gene studies of autism spectrum disorders in European populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Polymorphisms in the GPX-1 and MnSOD genes are associated with an increased risk of breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Determination of VNTR of the GPIba gene may prove useful for identifying high-risk individuals for MI.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Association of gene polymorphisms with myocardial infarction in individuals with or without conventional coronary risk factors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We found statistically significant differences (P < 0.01) between the healthy volunteers and patients with severe periodontitis in the following genes; gonadotropin-releasing hormone 1 (GNRH1), phosphatidylinositol 3-kinase regulatory 1 (PIK3R1), dipeptidylpeptidase 4 (DPP4), fibrinogen-like 2 (FGL2), and calcitonin receptor (CALCR).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[To investigate the association between M235T and G-6A polymorphism of AGT gene, insertion/deletion (I/D) polymorphism of ACE gene, Gly460Trp polymorphism of ADD1 gene, C825T polymorphism of GNB3 gene and essential hypertension in Xinjiang Kazakhs group as well as to identify the interactions of gene-gene and gene-environment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[CT + TT genotypes of GNB3 predominated in patients with hypertension (65%) compared to normotensive patients (12%) (p <0.01).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The TC patients exhibited a significantly higher frequency of the liver glutathione-S-transferase GST1*0 allele, whereas the GST1*2 frequency was two times higher in the control subjects than in the TC patients (0.2522 and 0.0953, respectively). The TC and control groups showed statistically significant differences in the frequencies of the following]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Del(GJB6-D13S1830) and GJB2/del(GJB6-D13S1830) mutations have been shown to be the second most frequent cause of deafness in different populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Low frequency of deafness-associated GJB2 variants in Kenya and Sudan and novel GJB2 variants.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[To determine the prevalence of GJB2 mutations among subjects with congenital, non-syndromic, sensorineural hearing loss, within a north Indian population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Common diversity in GH-CSH correlates with low 1-yr weight and with features of the metabolic syndrome in later life. GH-CSH genotype adds substantially to, but does not account for, the associations between low body weight, at birth and in infancy, and the metabolic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Association of warfarin dose with genes involved in its action and metabolism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Vocal cord and diaphragm paralysis, as clinical features of a French family with autosomal recessive Charcot-Marie-Tooth disease, associated with a new mutation in the GDAP1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[In conclusion, this pilot identified SNPs as potential markers that could predict hepatitis B patient response. These observations may help guide future large-scale studies in examining host SNPs for their clinical utility in predicting IFN response.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Increased frequency of pathogenic variants in GBA, the causative gene for Gaucher disease, has been suggested to be associated with Parkinson disease (PD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Evidence of association between gamma-aminobutyric acid type A receptor genes located on 5q34 and female patients with mood disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Association analysis of sequence variants of GABA(A) alpha6, beta2, and gamma2 gene cluster and alcohol dependence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We conclude that GABRA4 is involved in the etiology of autism and potentially increases autism risk through interaction with GABRB1. These results support the hypothesis that GABA receptor subunit genes are involved in autism, most likely via complex gene-gene interactions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Candidate genes for alcohol dependence: a review of genetic evidence from human studies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[These LD findings, together with the association results, suggest that the GABRA6 and GABRA1 genes account for alcohol susceptibility in Han and exert their genetic influences in a somewhat dominant and synergistic fashion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Systematic study of association of four GABAergic genes: glutamic acid decarboxylase 1 gene, glutamic acid decarboxylase 2 gene, GABA(B) receptor 1 gene and GABA(A) receptor subunit beta2 gene, with schizophrenia using a universal DNA microarray.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Complexity of the genotype-phenotype correlation in familial exudative vitreoretinopathy with mutations in the LRP5 and/or FZD4 genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[These studies should allow improved risk assessments for genetic counseling of women with premutation or intermediate-size alleles.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[3 premutation carriers (2 patients, 1 control) were detected. Of note, 1 of the affected premutation carriers had a heterozygous Parkin mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Screening of women within the parkinsonism clinical spectrum is unlikely to be productive in the absence of additional medical or family history suggestive of involvement of the FMR1 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[This suggests a general trend for higher genetic diversity among Africans; these rarer alleles could be African in origin and would have been lost or possibly were not present in the groups that gave rise to the Europeans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Genotypes defined by the mutational status of NPM1, FLT3, CEBPA, and MLL are associated with the outcome of treatment for patients with cytogenetically normal AML.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ We describe a rapid assay for the genotyping of the Gln5345Arg mutation using real-time fluorescence PCR to facilitate rapid processing of samples through combined amplification and detection steps. These characteristics are suitable for a clinical setting where high throughput diagnostic procedures are required. The frequency of this mutation within the Northern Ireland population has been estimated at 0.2%, concurring with previous findings that this mutation is a rare variant associated with AMD. A rapid diagnostic assay will facilitate a reliable and convenient evaluation of the frequency of the Gln5345Arg mutation and its association with AMD within other populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We provide the evidence that FGFR4 388Arg is an independent predictor of pCR following AC-Doc as NCT in PBC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Correlation of FGFR3 mutations and chromosomal alterations in bladder cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Serum levels of FGF-23 were increased in FD/MAS patients compared with normal age-matched controls and significantly higher in FD/MAS patients with renal phosphate wasting compared with those without, and correlated with disease burden bone turnover markers commonly used to assess disease activity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[As gene variants predisposing to thrombophilia and influencing the increased risk of vein thrombosis might influence response to local thrombolysis, the aim of the work was to characterize the pharmacogenetic conditions for local streptokinase treatment in patients with a deep vein thrombosis (DVT) of lower extremities based on the following polymorphism analyses: G1691A polymorphism of factor V (FV), G20210A polymorphism of prothrombin (PT), A4250G (Thr312Ala) polymorphism of fibrinogen-alpha (FGA), G(-455)A polymorphism of fibrinogen-beta (FGB), 4G/5G polymorphism of plasminogen activator inhibitor type 1(PAI-1) and insertion/deletion (I/D) polymorphism of tissue plasminogen activator (t-PA).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[European Atherosclerosis Research Study: genotype at the fibrinogen locus (G-455-A beta-gene) is associated with differences in plasma fibrinogen levels in young men and women from different regions in Europe. Evidence for gender-genotype-environment interaction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Polymorphisms in prothrombotic genes and their impact on ischemic stroke in a Sardinian population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Analysis of Fcgamma receptor haplotypes in rheumatoid arthritis: FCGR3A remains a major susceptibility gene at this locus, with an additional contribution from FCGR3B.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ Overall, the data indicate that the distribution of the FcgammaRIIIB alleles is significantly different in Amazon Indians from the distribution in Brazilian blood donors or African Brazilian patients with SCD, but that it is similar to the distributions reported in Asian populations. Moreover, the distribution of the FcgammaRIIA and FcgammaRIIIB alleles among Brazilian blood donors and SCD patients is comparable to the distributions reported in whites from the United States and Europe.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ Our data provide evidence for an association between FcgammaRIIIA allelic variants and coronary atherosclerosis. Genetic variation in this IgG-receptor may influence the clearance of antibodies by monocyte-derived macrophages involved in the pathogenesis of CAD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Single nucleotide polymorphism in asthma predisposing genes in children in Shanghai.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Association of interleukin-1 receptor antagonist +2018 gene polymorphism with Japanese chronic periodontitis patients using a novel genotyping method.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[In order to estimate the contribution of mutations at the fibrillin-1 locus (FBN1) to classical Marfan syndrome (MFS) and to study possible phenotypic differences between patients with an FBN1 mutation vs. without, a comprehensive molecular study of the FBN1 gene in a cohort of 93 MFS patients fulfilling the clinical diagnosis of MFS according to the Ghent nosology was performed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We analyzed FBN1 gene in 99 patients referred to our Center for Marfan Syndrome and Related Disorders (University of Florence, Florence, Italy): 85 were affected by MFS and 14 by other fibrillinopathies type I.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ These findings suggest that the FAS-1377G/A and FASL-844T/C polymorphisms may be genetic susceptibility factors for colorectal cancer among Chinese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Analysis of multiple candidate genes in association with phenotypes of multiple sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Pharmacogenetics of glatiramer acetate therapy for multiple sclerosis reveals drug-response markers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[In the present study we tested the role of the Factor VII G10976A and -C122T polymorphisms on the susceptibility to develop IS in a genetically homogenous and clinically well ascertained case-control study including 294 cases (median age 75 years; 176 males/118 females) and 286 controls (median age 73 years; 163 males/123 females) in Sardinia, Italy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Visceral obesity is also associated with a hypercoagulate state and elevated concentrations of procoagulant factors such as factor VII.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Epidemiological and genetic associations of activated factor XII concentration with factor VII activity, fibrinopeptide A concentration, and risk of coronary heart disease in men.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Hereditary risk factors for venous thrombosis do not predispose for severe preeclampsia. However, women who are carriers of the G20210A prothrombin gene mutation and the PAI-1 5G/5G genotype are at risk for early onset of severe preeclampsia. It appears that these risk factors do not induce the pathomechanism but accelerate the course of preeclampsia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Prevalence of factor V leiden mutation in patients with thrombosis in Tunisia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Inherited thrombophilia as the reason of recurrent miscarriges in the first trimester of pregnancy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[After accounting for multiple testing, 5 SNPs associated with VT risk were identified, 3 of which have not been previously reported.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The results of this study suggest that FVL mutation may be one of the important risk factors in developing CAD in northeast Turkey.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The association of protein S Tokushima-K196E with a risk of deep vein thrombosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Mutation frequencies of the thrombophilic state genes in Uzbekistan.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ Our data fail to document an independent significant influence of the investigated polymorphisms on the risk of severe preeclampsia. In an attempt to build a multigenetic model of severe preeclampsia, the combination of F5 Leiden, NOS 3 T768C, NOS 3 Glu298Asp, and ER alpha Pvu II was the most effective combination to predict the presence of severe preeclampsia in this small series of white women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The increased prevalence rate and coexistence of both FV and MTHFR found in this group of patients suggest that these mutations might increase the risk of arterial thrombosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Inherited thrombophilia is associated with pregnancy losses that occur after 12th gestational week in Serbian population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Our statistical method can determine whether increases in miscarriage are due to fetal genotype, maternal genotype, or both despite censoring.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ Increased PAI-1 and homocysteine concentrations are independent risk factors for MACE after successful coronary stenting, whereas Lp(a) and thrombophilic polymorphisms are not predictive.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Increased Factor V Leiden frequency is associated with venous thrombotic events among young Brazilian patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Individual coronary risk might be related to the presence of a critical accumulation detrimental polymorphisms]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ Both homozygosity and heterozygosity for FXIII Val34Leu predispose to idiopathic subconjunctival hemorrhage, emphasizing the role of Leu34 allele as inherited risk factor for spontaneous, especially recurrent, subconjunctival hemorrhages.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Homozygosity of the T allele of the 46 C-->T polymorphism in the F12 gene is a risk factor for acute coronary artery disease in the Spanish population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[ This study suggests that the 46 C-->T polymorphism is a genetic risk factor for IS in the Spanish population. In addition, our results confirm that the use of genetic linkage studies along with a case-control association study is an extremely valuable approach for identifying DNA variants that affect complex diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[An optimized DHPLC protocol for molecular testing of the EXT1 and EXT2 genes in hereditary multiple osteochondromas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Hormone receptor-related gene polymorphisms and prostate cancer risk in North Indian population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Further studies are needed to replicate our findings as well as to better elucidate the biological mechanisms of the modulation of ESR-, and ER- on male infertility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[In conclusion, our findings suggest the ERbeta allele 5 to be a protective factor. However, this has to be confirmed in a larger population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Association between estrogen receptor-beta gene polymorphisms and ovulatory dysfunctions in patients with menstrual disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[our findings suggest that the combined genotypes of CDK7 and ESR1 are associated with breast cancer risk among Korean women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[selected genetic polymorphisms of ESR1 and ESR2, overall, were not associated with prostate cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[Analysis of polymorphisms of the vitamin D receptor, estrogen receptor, and collagen Ialpha1 genes and their relationship with height in children with bone cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[The estrogen receptor 1 G594A polymorphism is associated with migraine susceptibility in two independent case/control groups.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
[We examined reported associations between radiographic hand osteoarthritis (OA) and single-nucleotide polymorphisms (SNP) in 2 candidate genes associated with OA in other joints: estrogen receptor alpha (ESR1) and beta (ESR2).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.