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was generated by: activity

c981f
organism name: Homo sapiens
source: R-HSA-422059
source: Q9UBU3-1
target: R-HSA-422096
target: Q9UBU3-1
type: Interaction

Synthesis, secretion, and deacylation of Ghrelin

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was generated by: activity

dda05
organism name: Homo sapiens
source: CHEBI:15422
source: R-HSA-2029963
target: CHEBI:16761
target: R-HSA-2029940
type: Interaction

Signaling by FGFR2

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has provenance: provenance
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supersedes: RA86zyNmS8KmlOJnPAbWK6kejHQ3xotbJ-sFYGwTfi0QU
was generated by: activity

e6eec
organism name: Homo sapiens
source: P35222
source: Q9HCK8
target: R-HSA-5368504
type: Interaction

TCF dependent signaling in response to WNT

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supersedes: RAAC8x8nxKFcyXx8tGzIdkPPv3ejiQCNx- -i7yHNUQYc
was generated by: activity

eab8f
organism name: Homo sapiens
source: http://identifiers.org/ncbigene/5592
target: http://identifiers.org/ncbigene/1432
type: Interaction

VEGFA-VEGFR2 Signaling Pathway

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supersedes: RAcKE8wVRg7OH9vz u5FzMUD2 FmUTfhKiTSMpaXeItnY
was generated by: activity

b9c09
organism name: Homo sapiens
source: R-HSA-5654305
source: Q06124
target: R-HSA-5654310
type: Interaction

Signaling by FGFR3

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supersedes: RA0u9HMj fKguBUhe6A5yjttRbsSiTSOUADNXIWC4sioY
was generated by: activity

b0ac5
organism name: Homo sapiens
source: R-HSA-5610612
target: Q9UMX1
type: Interaction

Hedgehog 'off' state

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supersedes: RAvqwVsSMJCk61AdRcI9ppU1GjA6E iS2SwyJ8 O1bb8s
was generated by: activity

dab76
organism name: Homo sapiens
source: R-HSA-389778
source: R-HSA-445002
target: R-HSA-2029159
target: Q13153
type: Interaction

RHO GTPases activate PAKs

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was generated by: activity

b737a
organism name: Homo sapiens
source: R-HSA-2993783
source: Q14676
target: R-HSA-4570497
target: P63279
type: Interaction

SUMOylation of DNA damage response and repair proteins

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has assertion: assertion
has provenance: provenance
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rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAYOMEPLLDSea6yKYfa8EAaFEfyMgd-xK2kR4W2HEyS-A
was generated by: activity

da02c
organism name: Homo sapiens
source: R-HSA-5637979
source: Q96QF0
target: R-HSA-5637982
type: Interaction

Assembly of the primary cilium

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has provenance: provenance
has publication info: publicationInfo
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supersedes: RA8NSz6cvdhKlyS Ca7uxAXUrYlNL7qgPGY7fIqIA7kZM
was generated by: activity

db9e4
organism name: Homo sapiens
source: R-HSA-5637464
source: Q14790
target: R-HSA-5637468
type: Interaction

TRAIL signaling

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type: Nanopublication
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supersedes: RA3tcWZmxDftGKU9pHXQ5LXlM6KChXqqYvMFiAnnCJEHg
was generated by: activity

b192d
organism name: Homo sapiens
source: R-HSA-5668442
target: R-HSA-5668475
target: R-HSA-5676550
target: Q99558
type: Interaction

TNFR2 non-canonical NF-kB pathway

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supersedes: RAO1WJObese81eV9oon4iyPv4gKguS6KqdQEXlW2Lf V8
was generated by: activity

b73bf
organism name: Homo sapiens
source: CHEBI:17509
source: CHEBI:18367
target: CHEBI:16708
target: CHEBI:58533
type: Interaction

Sulfur amino acid metabolism

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supersedes: RA rYuaN0pb0Fqo44iwoR-kWo-jKX0BKVUpxubfpTIgsA
was generated by: activity

eac2f
organism name: Bos taurus
source: ENSBTAG00000033983
target: ENSBTAG00000016156
type: Interaction

Serotonin Receptor 4/6/7 and NR3C Signaling

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has assertion: assertion
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supersedes: RAEkn3BEEEz7q7BLFHuIBnKi9ReQRmBzlkTXaqc PNei0
was generated by: activity

e9d18
organism name: Homo sapiens
source: R-HSA-5362428
target: R-HSA-5362546
type: Interaction

Hedgehog ligand biogenesis

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has assertion: assertion
has provenance: provenance
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supersedes: RAx-Tz76dN5m7hWOIF0 6aeH9BB9 9FJrHlJY z7xY4ro
was generated by: activity

fe99d
organism name: Homo sapiens
source: CHEBI:15422
source: R-HSA-8848773
target: CHEBI:16761
target: Q13882
target: Q99704
type: Interaction

Signaling by PTK6

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has assertion: assertion
has provenance: provenance
has publication info: publicationInfo
type: Nanopublication
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rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAvJXIZ6GHAvnLTOHjN9BykU86QukbVZgTue8hh2ooDno
was generated by: activity

f64ab
organism name: Homo sapiens
source: ENSG00000106080
target: Q9NWM8
type: Interaction

XBP1(S) activates chaperone genes

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has assertion: assertion
has provenance: provenance
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type: Nanopublication
created: 2018-06-09T11:20:45.005+02:00
rights: http://creativecommons.org/publicdomain/zero/1.0/
was generated by: activity

e93f9
organism name: Bos taurus
source: CHEBI:17996
target: CHEBI:17996
type: Interaction

Iron uptake and transport

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has assertion: assertion
has provenance: provenance
has publication info: publicationInfo
type: Nanopublication
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rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAHmEelnH1RuQ0xf4P9BZj4k 9cP HH4IRhL6WWp22eCw
was generated by: activity

idb0dbccc7
organism name: Homo sapiens
source: P09874
target: P49959
type: Interaction

DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM

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has assertion: assertion
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supersedes: RA1IJmVpMNnghBq8Oq yEf6Mzlnq4s914pWvMakZTp4vE
was generated by: activity

d8cb0
organism name: Homo sapiens
source: CHEBI:15414
source: R-HSA-4657030
target: CHEBI:16680
target: R-HSA-5638139
type: Interaction

Chromatin modifying enzymes

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supersedes: RAGJAJFSKwOL8xbv0Ve72BlR-uze4RMqdQJk-aQNl1Y1g
was generated by: activity

a5417
organism name: Homo sapiens
source: Q86T03
target: Q86T03
type: Interaction

Regulation of TP53 Activity through Acetylation

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supersedes: RAv0OkF6WRNElhMYiV1afvH52ddAwZjG6KKfnWDZDjkrE
was generated by: activity

ca01e
organism name: Homo sapiens
source: CHEBI:15378
source: CHEBI:15422
source: CHEBI:16474
source: CHEBI:29985
target: CHEBI:16761
target: CHEBI:17232
target: CHEBI:18009
target: CHEBI:18367
type: Interaction

Amino acid synthesis and interconversion (transamination)

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supersedes: RAVs-E jpsvPC-pPI2D DXCwvcVrznTHdGJTbat5jQkE4
was generated by: activity

fc682
organism name: Homo sapiens
source: R-HSA-165697
target: P06730
target: Q13541
type: Interaction

mTOR signalling

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has provenance: provenance
has publication info: publicationInfo
type: Nanopublication
created: 2018-06-09T11:20:45.005+02:00
rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAVgWG nruVCb0K0B01BDlKz6DKthkEURwTBa1XCtxr5I
was generated by: activity

fcceb
organism name: Homo sapiens
source: R-HSA-5683809
source: R-HSA-5684135
target: R-HSA-5684107
type: Interaction

HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)

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has assertion: assertion
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supersedes: RAHzDkHj4pVYHlQPbmbCMHUq41eI1PY8vUrJpgRAbcJzU
was generated by: activity

df525
organism name: Homo sapiens
source: R-HSA-3209194
source: R-HSA-6804745
target: R-HSA-6804885
type: Interaction

Regulation of TP53 Expression and Degradation

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rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAYC8AnsXfyw LZUYmzNVWlGKDVs kWHwFyudeIf1duGo
was generated by: activity

c4ade
organism name: Homo sapiens
source: CHEBI:15378
source: CHEBI:16474
source: CHEBI:17898
target: CHEBI:17336
target: CHEBI:18009
type: Interaction

Signaling by Retinoic Acid

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has provenance: provenance
has publication info: publicationInfo
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rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAtpeHq6VYeE8dIjjD9SApDNK bbv04KEIBin7RQVMBMc
was generated by: activity

a30e3
organism name: Homo sapiens
source: R-HSA-113595
source: R-HSA-5610605
target: R-HSA-5610612
type: Interaction

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has provenance: provenance
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type: Nanopublication
created: 2018-06-09T11:20:45.005+02:00
rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAWGVqAMRNjBRDa-B7UequqKrkiR30bavbZDZfxCmBNcQ
was generated by: activity

c999a
organism name: Homo sapiens
source: CHEBI:15379
source: CHEBI:57912
target: CHEBI:18377
type: Interaction

Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism

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rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAfC2GobOI-4Ws4E43-u7KzWQo hZn3bXMqqhNSqr4B c
was generated by: activity

b4da4
organism name: Homo sapiens
source: ENSG00000143321
target: P51858
type: Interaction

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has assertion: assertion
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has publication info: publicationInfo
type: Nanopublication
created: 2018-06-09T11:20:45.005+02:00
rights: http://creativecommons.org/publicdomain/zero/1.0/
was generated by: activity

f2e96
organism name: Bos taurus
source: CHEBI:15377
source: CHEBI:15422
source: CHEBI:29108
target: CHEBI:16761
target: CHEBI:18367
target: CHEBI:29108
type: Interaction

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has assertion: assertion
has provenance: provenance
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type: Nanopublication
created: 2018-06-09T11:20:45.005+02:00
rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RA-wPmlvK65h6LQjIzUR6I29OBAdPzbTO-v4IcRllIag8
was generated by: activity

dfcdc
organism name: Homo sapiens
source: R-HSA-5692928
target: R-HSA-5692940
target: P56817
type: Interaction

Amyloid fiber formation

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has assertion: assertion
has provenance: provenance
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rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RA2YBHQl-KpgaBn814LiWYK 948o02lRnnl9tjCGROmdo
was generated by: activity

a76a8
organism name: Homo sapiens
source: R-HSA-5649682
target: CHEBI:29115
target: R-HSA-5649690
type: Interaction

Base-Excision Repair, AP Site Formation

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supersedes: RA4Zhu9cLcLM3Rg2xMGlpnPnTRSfV05rPMc7xQeibmWwE
was generated by: activity

c9bd4
organism name: Homo sapiens
source: CHEBI:15996
source: R-HSA-165191
target: CHEBI:17552
target: R-HSA-165189
type: Interaction

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has assertion: assertion
has provenance: provenance
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type: Nanopublication
created: 2018-06-09T11:20:45.005+02:00
rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAyBEBnZ9AQmSsgjIqT-9aE nQsLBJCdU7XHzq1Ji8yDQ
was generated by: activity

cdd98
organism name: Homo sapiens
source: R-HSA-377420
source: P31946
target: R-HSA-5672861
type: Interaction

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has provenance: provenance
has publication info: publicationInfo
type: Nanopublication
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rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RA6OgovWDdwnjr0xU1RpVqpjiFN5H5vc6rbfZMp4S5GeI
was generated by: activity

a642e
organism name: Homo sapiens
source: CHEBI:32513
target: CHEBI:16526
target: CHEBI:18295
type: Interaction

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has assertion: assertion
has provenance: provenance
has publication info: publicationInfo
type: Nanopublication
created: 2018-06-09T11:20:45.005+02:00
rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAzqCZN7DuQs TImB huOD9ZbgGGpNnAKSkTP7z1uu4VA
was generated by: activity

e69d1
organism name: Homo sapiens
source: R-HSA-5686692
source: Q96SD1
target: R-HSA-5686907
type: Interaction

Nonhomologous End-Joining (NHEJ)

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has provenance: provenance
has publication info: publicationInfo
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rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAHyAyePQvwmhvwvJHXJlAwV3sc55Kd6XsdkLO4FHpiAs
was generated by: activity

df271
organism name: Homo sapiens
source: ENSG00000158169
source: R-HSA-3222171
target: R-HSA-6806590
type: Interaction

TP53 Regulates Transcription of DNA Repair Genes

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has provenance: provenance
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created: 2018-06-09T11:20:45.005+02:00
rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAys chY7AAaMQkb5JMgeBpT5z-A6jVbpGzJ1vit0MB 0
was generated by: activity

cf6ab
organism name: Homo sapiens
source: R-HSA-4416737
target: R-HSA-1504204
target: R-HSA-196206
target: P25054
target: P35222
target: P48729
target: Q5JTC6
type: Interaction

RAJ2nLa6J8s8YoR7rrSpJF-2PqWpceMPo-O57FGOc1QfU
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has provenance: provenance
has publication info: publicationInfo
type: Nanopublication
created: 2018-06-09T11:20:45.005+02:00
rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAOxtFOq8X4isdfmWYR3PWvujSZdxLthPoMstpIRrhLZ0
was generated by: activity

b938f
organism name: Homo sapiens
source: http://identifiers.org/ncbigene/5747
target: http://identifiers.org/ncbigene/7414
type: Interaction

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ec082
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target: R-HSA-4411387
type: Interaction

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e10c5
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target: R-ALL-2534423
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Retinoid metabolism and transport

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dbb49
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C-type lectin receptors (CLRs)

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f6c11
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Branched-chain amino acid catabolism

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a6d23
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Oncogene Induced Senescence

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be573
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b36fd
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c1555
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fc47a
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cde9d
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dcad7
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e4963
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type: Interaction

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ad394
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rRNA modification in the nucleus and cytosol

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f230b
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Mitophagy

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c434f
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Uptake and function of anthrax toxins

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bb84b
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Sialic acid metabolism

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d389a
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Golgi to ER Retrograde Transport

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idcb57a389
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Angiopoietin Like Protein 8 Regulatory Pathway

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a4edb
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a1577
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Monoamine Transport

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e9d57
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TP53 Regulates Transcription of Cell Death Genes

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fb69d
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cd2eb
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b2955
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Regulation of TP53 Activity through Association with Co-factors

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d7dd1
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aea0c
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type: Interaction

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d7dcb
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df1ab
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type: Interaction

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c8557
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type: Interaction

DNA Double Strand Break Response

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e3835
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Beta-catenin independent WNT signaling

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ee4d8
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type: Interaction

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f1f75
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type: Interaction

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d0330
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source: P56817
target: P56817
type: Interaction

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c63b0
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target: R-HSA-3240767
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Oxidative Stress Induced Senescence

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c732e
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NIK-->noncanonical NF-kB signaling

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ba0c8
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Signaling by Leptin

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f84ce
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Intra-Golgi and retrograde Golgi-to-ER traffic

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was generated by: activity

R-HSA-8848415
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organism name: Homo sapiens

d5811
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source: Q13882
target: R-HSA-8848415
type: Interaction

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was generated by: activity

ea1f3
organism name: Homo sapiens
source: R-HSA-167717
source: R-HSA-199981
source: R-HSA-432668
source: R-HSA-432690
source: R-HSA-435031
source: P49407
target: R-HSA-432700
type: Interaction

trans-Golgi Network Vesicle Budding

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supersedes: RA6XG7UNNgYErDDVo0fJY-o73LbelHhhaScUDj8r5VmXw
was generated by: activity

dbea2
organism name: Bos taurus
source: ENSBTAG00000017582
target: ENSBTAG00000017976
type: Interaction

DNA Damage Response

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was generated by: activity

ae912
organism name: Homo sapiens
source: CHEBI:16618
source: R-HSA-5654170
source: P19174
target: R-HSA-5654155
type: Interaction

Signaling by FGFR1

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was generated by: activity

c3827
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source: ENSBTAG00000031625
target: http://identifiers.org/cas/51-41-2
type: Interaction

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was generated by: activity

ef6c8
organism name: Homo sapiens
source: CHEBI:15378
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target: CHEBI:15378
target: CHEBI:29108
type: Interaction

Cardiac conduction

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supersedes: RAezXbAGap32FYDIsdRWBvnk1cDdV7j nfFJQgqMb3o-w
was generated by: activity

fe707
organism name: Homo sapiens
source: R-HSA-6807786
source: R-HSA-6807800
target: R-HSA-6807803
type: Interaction

ER to Golgi Anterograde Transport

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was generated by: activity

ide3ff3f41
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source: ENSG00000132170
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type: Interaction

Transcription factor regulation in adipogenesis

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was generated by: activity

e978f
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target: R-HSA-5675472
type: Interaction

Regulated Necrosis

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ff4e6
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source: CHEBI:15422
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target: CHEBI:16761
target: R-HSA-5682599
type: Interaction

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supersedes: RAnwyVpKjnwFIzi346DEldciMB5vS1tRH9e8KjQfpDIg0
was generated by: activity

a3536
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source: ENSBTAG00000017075
target: http://identifiers.org/cas/56-12-2
type: Interaction

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was generated by: activity

d65cc
organism name: Homo sapiens
source: R-HSA-5666096
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target: R-HSA-5666105
type: Interaction

RHO GTPases Activate Formins

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was generated by: activity

d4d8d
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source: CHEBI:15377
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Surfactant metabolism

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was generated by: activity

ab607
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source: CHEBI:15422
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target: CHEBI:16761
target: CHEBI:18367
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type: Interaction

Metabolism of folate and pterines

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was generated by: activity

f28d2
organism name: Homo sapiens
source: CHEBI:32682
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target: CHEBI:15729
target: CHEBI:16344
type: Interaction

Metabolism of polyamines

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supersedes: RA a4BAZAYaTbWfEe50HBCOjqFqjMqm5OCsjF1PxIdx8Q
was generated by: activity

b40ee
organism name: Homo sapiens
source: ENSG00000090520
target: Q9UBS4
type: Interaction

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was generated by: activity

b82ed
organism name: Homo sapiens
source: P43146
source: Q9UKG1
target: R-HSA-373668
type: Interaction

Ligand-independent caspase activation via DCC

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supersedes: RAm2 4KWsvrt6vmN5yDzzyV9Sg0bMPF984zOIwNoKWpZI
was generated by: activity

b569f
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source: CHEBI:15377
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source: CHEBI:29991
source: CHEBI:58359
target: CHEBI:16027
target: CHEBI:29888
target: CHEBI:29985
target: CHEBI:58048
type: Interaction

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supersedes: RAWtlBvH2Jhsde2pesWHecDpAFFv vouO0YdTgtXMk0v8
was generated by: activity

f3658
organism name: Homo sapiens
source: Q96FI4
target: R-HSA-5649670
type: Interaction

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supersedes: RATGmD3 cKwASY08TcUR6zWqvnR8BTrdhFYpqyyPk2f-k
was generated by: activity

e773c
organism name: Homo sapiens
source: ENSG00000161642
source: R-HSA-3222171
target: R-HSA-6803418
type: Interaction

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was generated by: activity

c0bf1
organism name: Bos taurus
source: CHEBI:18248
target: CHEBI:18248
type: Interaction

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was generated by: activity

ab7ac
organism name: Homo sapiens
source: CHEBI:15422
source: R-HSA-5672141
target: CHEBI:16761
target: R-HSA-5673748
type: Interaction

Macroautophagy

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was generated by: activity

e0294
organism name: Homo sapiens
source: CHEBI:15422
source: R-HSA-1458897
target: CHEBI:16761
target: R-HSA-1458890
type: Interaction

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supersedes: RAFZ47CcSUP3lYk dvRkTTYnAytbS511fvGW8EArtZjBU
was generated by: activity

b3be0
organism name: Homo sapiens
source: R-HSA-140946
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target: R-HSA-5357866
type: Interaction

TNF signaling

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supersedes: RAcJmBVBkjPRcLcdWPvqzqpGIG1w5r-0l5chqNlmISQTY
was generated by: activity

f20d8
organism name: Homo sapiens
source: http://identifiers.org/ncbigene/7430
target: http://identifiers.org/ncbigene/824
type: Interaction

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supersedes: RA-Aro4rG2Hm6JrT2u5Xvpf7szhzxrSAGw-OO3g1Lsawk
was generated by: activity

bba15
organism name: Homo sapiens
source: O75462
source: Q9UBD9
target: R-HSA-5696496
type: Interaction

IL-6-type cytokine receptor ligand interactions

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supersedes: RAdJ2XwqXbp8ECI5fmN3GhAMv2TlBpehLIiecLj1nipk0
was generated by: activity

b7b09
organism name: Homo sapiens
source: R-HSA-5668423
source: R-HSA-5668435
target: R-HSA-5668447
type: Interaction

RAK MI fPdp9nWd2YbYJ74I4ZgFH Hz3OAapnZg4do7Zw
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rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAqIhm-Q2InIUWFagrlXYUSi4uM0cop3X3IO65T9LE3wE
was generated by: activity

ENSBTAG00000001069
type: GeneProduct
type: Protein
type: Rna
is part of: WP1010
is part of: WP1018
is part of: WP1044
is part of: WP1045
is part of: WP1075
is part of: WP1078
is part of: WP1083
organism name: Bos taurus

id72cb0404
organism name: Bos taurus
source: ENSBTAG00000014741
target: ENSBTAG00000001069
type: Interaction

TP53 Network

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supersedes: RA6tROEFALQ4SYWxht hXiFOOtyiza0CKs2QIFcujnRyo
was generated by: activity

b774c
organism name: Homo sapiens
source: R-HSA-5672001
source: P78352
target: R-HSA-5672002
type: Interaction

RHO GTPases activate CIT

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supersedes: RAaaUjZfaznwzH8AXGfe1q16akcOQUQWX8dJOh8zTXT1o
was generated by: activity

e5d4f
organism name: Homo sapiens
source: CHEBI:15377
source: CHEBI:17855
target: CHEBI:18035
target: CHEBI:33575
type: Interaction

Keratinization

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supersedes: RAxq3xfcR0E7jgDg5G ML7cMTRn2PGMA8qdwqiaT78-b4
was generated by: activity

ee63e
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source: CHEBI:15422
source: CHEBI:17515
source: CHEBI:57305
target: CHEBI:16761
target: CHEBI:16856
target: CHEBI:18367
type: Interaction

Phase II - Conjugation of compounds

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supersedes: RAg9I7fzwyHASuqksMfyka5Qn8wcYJCTWQExTXifLZz-Y
was generated by: activity

b78a3
organism name: Homo sapiens
source: R-HSA-8866325
source: P02654
source: P55056
target: R-HSA-8855875
type: Interaction

Plasma lipoprotein assembly, remodeling, and clearance

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supersedes: RAbuGGyoruwa4lZApYJ3oZQuQ7xKjtEB1cY3sHpfKMeaw
was generated by: activity

b77d5
organism name: Homo sapiens
source: CHEBI:15414
source: P38117
target: CHEBI:16680
target: P38117
type: Interaction

Protein methylation

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supersedes: RAV7vnR0XtFV4zDQd9kaMhX8T6SG5hdqycXso 7IUFCwc
was generated by: activity

ac7cb
organism name: Homo sapiens
source: CHEBI:18066
source: R-HSA-3321999
target: CHEBI:17659
target: R-HSA-3322056
type: Interaction

Glycogen metabolism

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supersedes: RA5jm9TnFWN6V4PFvSoBGcUn-55raJDZrwkGaM87hjlGM
was generated by: activity

f6b16
organism name: Homo sapiens
source: R-HSA-2993783
source: R-HSA-8864386
target: R-HSA-8865822
target: P63279
type: Interaction

Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors

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supersedes: RAVYvvSY5j2UVGUxrxcwlabkI2LYkybBpQar7BJ1UmAMM
was generated by: activity

a817e
organism name: Homo sapiens
source: ENSG00000131876
target: P09661
type: Interaction

Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation

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supersedes: RA6b75NIwyTbU0be7kVdl6S-gHbp37oV-kLej3FafvthI
was generated by: activity

idceb26968
organism name: Homo sapiens
source: Q13535
target: Q14683
type: Interaction

DNA IR-damage and cellular response via ATR

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was generated by: activity

eb86f
organism name: Homo sapiens
source: CHEBI:15422
source: R-ALL-500173
target: CHEBI:16761
target: R-ALL-500088
type: Interaction

Nucleotide salvage

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supersedes: RAk10TjfFdJCTzqYbgrbygMLLxCBVLwXFM8ZyzTtFPxx4
was generated by: activity

c2a6c
organism name: Homo sapiens
source: ENSG00000114315
target: ENSG00000168267
type: Interaction

PTF1A related regulatory pathway

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was generated by: activity

b8a53
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source: CHEBI:57930
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target: CHEBI:15377
target: CHEBI:73316
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type: Interaction

Interconversion of nucleotide di- and triphosphates

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caba2
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type: Interaction

Transcriptional regulation by RUNX3

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fa5cf
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Transcription from mitochondrial promoters

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Glucose metabolism

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ded24
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Neurexins and neuroligins

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Signaling by MET

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ebd76
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Deubiquitination

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a1cd5
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aaa77
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Pentose phosphate pathway (hexose monophosphate shunt)

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e23d0
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Interleukin-6 family signaling

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f7595
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Interleukin-10 signaling

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type: Interaction

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b5828
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Transcriptional regulation by RUNX1

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a66d5
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target: CHEBI:17552
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type: Interaction

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adcad
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Interleukin-4 and 13 signaling

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d3f72
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type: Interaction

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af252
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RET signaling

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fa8cc
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Nucleobase catabolism

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e3588
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source: R-HSA-8865330
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type: Interaction

RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)

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e5237
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Regulation of mitotic cell cycle

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dbea3
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Cellular hexose transport

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a3e07
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target: R-HSA-8955941
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type: Interaction

Neddylation

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aa025
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target: R-HSA-6786783
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type: Interaction

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b9e46
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target: CHEBI:16761
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target: CHEBI:18367
type: Interaction

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f0cb1
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Regulation of RUNX1 Expression and Activity

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dc5a8
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target: CHEBI:29101
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type: Interaction

Ion channel transport

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e3263
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Cilium Assembly

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d8d11
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target: R-HSA-6783276
type: Interaction

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f1b65
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type: Interaction

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d0c97
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source: CHEBI:15422
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target: CHEBI:29888
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type: Interaction

Protein ubiquitination

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e1881
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type: Interaction

Phase I - Functionalization of compounds

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c90c6
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target: O00501
type: Interaction

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dd2e4
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target: R-HSA-5624072
target: A6NIH7
target: O75695
type: Interaction

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ea5c8
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target: CHEBI:15346
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type: Interaction

Fatty acyl-CoA biosynthesis

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e0466
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target: R-HSA-8851897
type: Interaction

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df012
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target: CHEBI:15377
target: CHEBI:18009
target: CHEBI:34310
type: Interaction

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c9ac3
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source: Q13761
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target: R-HSA-8878120
type: Interaction

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a27dd
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target: CHEBI:17552
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type: Interaction

RAB GEFs exchange GTP for GDP on RABs

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da05d
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c00c5
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Neutrophil degranulation

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Collagen chain trimerization

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Clathrin-mediated endocytosis

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Metabolism of Tetrahydrocannabinol (THC)

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Synaptic adhesion-like molecules

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Digestion

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a8909
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Chromatin organization

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edfc9
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Regulation of TLR by endogenous ligand

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RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

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Antimicrobial peptides

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Nucleobase biosynthesis

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caccc
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PTEN Regulation

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d6b87
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c1d28
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e3d51
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Carboxyterminal post-translational modifications of tubulin

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c9fe9
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b0764
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Import of palmitoyl-CoA into the mitochondrial matrix

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dd61e
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a4a8d
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d2318
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fcc8c
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f0d2b
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d0eaa
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f3986
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Catabolism of glucuronate to xylulose-5-phosphate

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f341a
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e2e66
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Galactose catabolism

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a8aa7
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Receptor-type tyrosine-protein phosphatases

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d3c91
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fb7b8
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a3f05
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Ketone body metabolism

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E3 ubiquitin ligases ubiquitinate target proteins

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Fibrin Complement Receptor 3 Signaling Pathway

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Other interleukin signaling

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Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models

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id9745fb59
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EMT transition in Colorectal Cancer

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RNA Polymerase I Transcription

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c94db
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c94bc
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d6ca2
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ad291
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RAB geranylgeranylation

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a8b0e
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Tryptophan catabolism leading to NAD+ production

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d8541
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Nicotinate metabolism

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bd71c
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Processing of SMDT1

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Intracellular oxygen transport

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c8530
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fe9e6
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dffd1
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f2397
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RNA Polymerase III Transcription

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bd7cd
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Reelin signalling pathway

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Listeria monocytogenes entry into host cells

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c52f3
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d7e82
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d97f3
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a54f8
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a7030
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ea9aa
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cf35a
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be5a8
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b8348
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fbe36
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Mitochondrial Fatty Acid Beta-Oxidation

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TBC/RABGAPs

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HSP90 chaperone cycle for steroid hormone receptors (SHR)

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Choline catabolism

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c4536
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type: Interaction

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was generated by: activity

f400f
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type: Interaction

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b0a40
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f2351
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was generated by: activity

cf79a
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type: Interaction

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c77ee
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type: Interaction

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f4ce2
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source: P42685
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target: R-HSA-8847960
type: Interaction

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was generated by: activity

ba1d2
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source: O95786
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type: Interaction

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was generated by: activity

idcc616bcc
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Mitochondrial Unfolded-Protein Response (UPRmt)

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d39ad
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Estrogen metabolism

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was generated by: activity

b7723
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ATM Signaling Pathway

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c587d
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type: Interaction

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was generated by: activity

ac27c
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type: Interaction

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was generated by: activity

b588d
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p53 signal pathway

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d9db0
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type: Interaction

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edcfe
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type: Interaction

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af9a7
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c2de4
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type: Interaction

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idf6da08cb
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ErbB Signaling Pathway

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e143d
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Senescence and Autophagy in Cancer

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d2f1e
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e6675
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Monoamine Transport

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f598e 1
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TCA Cycle

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type: Protein

ed1ea
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e9ff8
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Serotonin Receptor 4/6/7 and NR3C Signaling

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aff0c
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df773
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ff038
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Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways

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c46bf
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type: Interaction

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adc00
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Serotonin Receptor 2 and ELK-SRF/GATA4 signaling

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f82c5
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type: Interaction

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a4f29
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type: Interaction

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was generated by: activity

c828e
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was generated by: activity

id32728cf2
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type: Interaction

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was generated by: activity

fe480
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type: Interaction

RAIM4Uk17HsVIXy8VQ9xxbV1v2kDSZ7wlzoEGPrya2gMc
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was generated by: activity

a4989
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target: http://identifiers.org/ncbigene/1958
type: Interaction

RAAM8jdJgzXd3ciCB PuTqUWnrk4chmuakLi6cfM0GA6o
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supersedes: RATFNazUNYWPF 7qHlGXws2V8fjS5hP2fieekJK0-HPxM
was generated by: activity

HMDB01022
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organism name: Anopheles gambiae
organism name: Caenorhabditis elegans
organism name: Homo sapiens

id56459e3d
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source: HMDB00208
target: HMDB01022
target: HMDB01487
target: HMDB01967
type: Interaction

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DNA Damage Response

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MAPK Signaling Pathway

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Serotonin Receptor 2 and STAT3 Signaling

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Arylamine metabolism

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Metabolism of nitric oxide

Signaling by VEGF

Opioid Signalling

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Folate Metabolism

Vitamin B12 Metabolism

Selenium Micronutrient Network

Folate Metabolism

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Integration of energy metabolism

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Fatty acid, triacylglycerol, and ketone body metabolism

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Cell Division: First embryonic mitosis

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Statin Pathway

Statin Pathway

Statin Pathway

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Folic Acid Network

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Unfolded Protein Response (UPR)

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Cell surface interactions at the vascular wall

Costimulation by the CD28 family

GP1b-IX-V activation signalling

GPCR downstream signaling

GPVI-mediated activation cascade

Interleukin-3, 5 and GM-CSF signaling

NGF signalling via TRKA from the plasma membrane

Signaling by EGFR

Signaling by Insulin receptor

Signaling by PDGF

TCR signaling

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Complement cascade

Formation of Fibrin Clot (Clotting Cascade)

Response to elevated platelet cytosolic Ca2+

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DNA Damage Reversal

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EBV LMP1 signaling

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HMDB01388
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Selenium Micronutrient Network

Folic Acid Network

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Mitotic G1-G1/S phases

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TCR Signaling Pathway

IL-3 Signaling Pathway

ACE Inhibitor Pathway

TGF beta Signaling Pathway

TGF Beta Signaling Pathway

Endochondral Ossification

Cell Cycle

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Q8TEY5
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Oxidation by Cytochrome P450

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Eicosanoid Synthesis

Eicosanoid Synthesis

Eicosanoid Synthesis

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Fluoropyrimidine Activity

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One Carbon Metabolism

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Circadian Clock

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Hexose transport

Metabolism of water-soluble vitamins and cofactors

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DNA Damage Bypass

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SIDS Susceptibility Pathways

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One Carbon Metabolism

One Carbon Metabolism

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Apoptosis

FAS pathway and Stress induction of HSP regulation

TNF alpha Signaling Pathway

Matrix Metalloproteinases

Toll-like receptor signaling pathway

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TCA Cycle

Valine, leucine and isoleucine degradation

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Wnt Signaling Pathway and Pluripotency

ErbB Signaling Pathway

G1 to S cell cycle control

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Angiogenesis

Apoptotic execution phase

Integrin alphaIIb beta3 signaling

NCAM signaling for neurite out-growth

Netrin-1 signaling

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Mitotic G2-G2/M phases

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miRNAs involved in DNA damage response

TP53 Network

Apoptosis Modulation and Signaling

Cell Cycle

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ABC-family proteins mediated transport

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Synthesis of DNA

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Telomere Maintenance

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Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

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