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[As predicted from the association between these five polymorphisms and risk of estrogen-positive or estrogen-negative breast cancer in the general population, differential associations of these polymorphisms with breast cancer risk were found for BRCA1 and BRCA2 mutation carriers presumably because BRCA1 breast cancer tumors are predominantly ER-negative and are biologically distinct from BRCA2 breast cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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