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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAzcY23LkHbF57y0OBj7QGt6RlXIo5hUv15eBVgnMI_DA#_5 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAzcY23LkHbF57y0OBj7QGt6RlXIo5hUv15eBVgnMI_DA#_4 http://www.w3.org/ns/prov#value Resistin causes defective AMPK activation in response to insulin. Since AMPK signaling affects insulin-sensitive glucose metabolism (19 22) and since AMPK can act upstream of Akt signaling (23, 24), we assessed whether resistin overexpression alters AMPK activity. As demonstrated in Figure 7, AMPK phosphorylation (Thr172) was reduced by 60%, 35%, and 64% (P 0.01) in the skeletal muscle, adipose tissue, and liver of rats injected with Adv-resistin, respectively, while AMPK protein content remained unchanged. http://www.tkuhn.ch/bel2nanopub/RAzcY23LkHbF57y0OBj7QGt6RlXIo5hUv15eBVgnMI_DA#_4 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/15254589 http://www.tkuhn.ch/bel2nanopub/RAzcY23LkHbF57y0OBj7QGt6RlXIo5hUv15eBVgnMI_DA#_5 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAzcY23LkHbF57y0OBj7QGt6RlXIo5hUv15eBVgnMI_DA#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/15254589 http://www.tkuhn.ch/bel2nanopub/RAzcY23LkHbF57y0OBj7QGt6RlXIo5hUv15eBVgnMI_DA#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAzcY23LkHbF57y0OBj7QGt6RlXIo5hUv15eBVgnMI_DA#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAzcY23LkHbF57y0OBj7QGt6RlXIo5hUv15eBVgnMI_DA#_4 http://www.tkuhn.ch/bel2nanopub/RAzcY23LkHbF57y0OBj7QGt6RlXIo5hUv15eBVgnMI_DA#pubinfo http://www.tkuhn.ch/bel2nanopub/RAzcY23LkHbF57y0OBj7QGt6RlXIo5hUv15eBVgnMI_DA http://purl.org/dc/terms/created 2014-07-03T14:32:25.927+02:00 http://www.tkuhn.ch/bel2nanopub/RAzcY23LkHbF57y0OBj7QGt6RlXIo5hUv15eBVgnMI_DA http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAzcY23LkHbF57y0OBj7QGt6RlXIo5hUv15eBVgnMI_DA http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234