@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP617022.RAzSaix7sEnchB-LVXcn1dcoNiFaZviskqV-6r85j6NLc130_head { this: np:hasAssertion dgn-np:NP617022.RAzSaix7sEnchB-LVXcn1dcoNiFaZviskqV-6r85j6NLc130_assertion; np:hasProvenance dgn-np:NP617022.RAzSaix7sEnchB-LVXcn1dcoNiFaZviskqV-6r85j6NLc130_provenance; np:hasPublicationInfo dgn-np:NP617022.RAzSaix7sEnchB-LVXcn1dcoNiFaZviskqV-6r85j6NLc130_publicationInfo; a np:Nanopublication . dgn-np:NP617022.RAzSaix7sEnchB-LVXcn1dcoNiFaZviskqV-6r85j6NLc130_assertion a np:Assertion . dgn-np:NP617022.RAzSaix7sEnchB-LVXcn1dcoNiFaZviskqV-6r85j6NLc130_provenance a np:Provenance . dgn-np:NP617022.RAzSaix7sEnchB-LVXcn1dcoNiFaZviskqV-6r85j6NLc130_publicationInfo a np:PublicationInfo . } dgn-np:NP617022.RAzSaix7sEnchB-LVXcn1dcoNiFaZviskqV-6r85j6NLc130_assertion { miriam-gene:3630 a ncit:C16612 . lld:C1397307 a ncit:C7057 . dgn-gda:DGNbc43d0a13620c35eba5d7803fda7142c sio:SIO_000628 miriam-gene:3630, lld:C1397307; a sio:SIO_001121 . } dgn-np:NP617022.RAzSaix7sEnchB-LVXcn1dcoNiFaZviskqV-6r85j6NLc130_provenance { dgn-np:NP617022.RAzSaix7sEnchB-LVXcn1dcoNiFaZviskqV-6r85j6NLc130_assertion dcterms:description "[A novel PAR2 antagonist, GB88 (5-isoxazoyl-Cha-Ile-spiroindene-1,4-piperidine), given orally at 10 mg/kg/d (wk 8-16) reduced body weight by ∼10% in obese rats fed a high-carbohydrate high-fat (HCHF) diet for 16 wk, and strongly attenuated adiposity, adipose tissue inflammation, infiltrated macrophages and mast cells, insulin resistance, and cardiac fibrosis and remodeling; while reversing liver and pancreatic dysfunction and normalizing secretion of PAR2-directed glucose-stimulated insulin secretion in MIN6 β cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:23964081; prov:wasDerivedFrom dgn-void:befree-20140225; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP617022.RAzSaix7sEnchB-LVXcn1dcoNiFaZviskqV-6r85j6NLc130_publicationInfo { this: dcterms:created "2014-10-02T12:38:13+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetrdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v2.1.0.0" . dgn-void:disgenetrdf pav:version "v2.1.0" . }