sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_6 ; pav:version "20131211" . sub:_5prov:value "The extrinsic pathway is activated in vivo by TNF family ligands that engage DD-containing receptors, resulting in activation of DED-containing caspases. The 'death ligands' are expressed on CTLs, NK cells, and other types of immune-relevant cells (activated monocytes/macrophages and dendritic cells) and are used as weapons for eradication of transformed cells (Locksley et al., 2001). tumor suppression by cellular immune mechanisms. For example, Fas-Ligand (FasL) is important for CTL-mediated killing of some tumor targets, and TRAIL (Apo2- Ligand) is critical for NK-mediated tumor suppression." ; prov:wasQuotedFrompubmed:12559172 . sub:_6rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:12559172 ; prov:wasDerivedFrombeldoc: , sub:_5 . }