@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP822240.RAyprcZlxFJmk3fc6P2pBI2YUwLQk_mopxTt3KVNF04j4130_head { this: np:hasAssertion dgn-np:NP822240.RAyprcZlxFJmk3fc6P2pBI2YUwLQk_mopxTt3KVNF04j4130_assertion; np:hasProvenance dgn-np:NP822240.RAyprcZlxFJmk3fc6P2pBI2YUwLQk_mopxTt3KVNF04j4130_provenance; np:hasPublicationInfo dgn-np:NP822240.RAyprcZlxFJmk3fc6P2pBI2YUwLQk_mopxTt3KVNF04j4130_publicationInfo; a np:Nanopublication . dgn-np:NP822240.RAyprcZlxFJmk3fc6P2pBI2YUwLQk_mopxTt3KVNF04j4130_assertion a np:Assertion . dgn-np:NP822240.RAyprcZlxFJmk3fc6P2pBI2YUwLQk_mopxTt3KVNF04j4130_provenance a np:Provenance . dgn-np:NP822240.RAyprcZlxFJmk3fc6P2pBI2YUwLQk_mopxTt3KVNF04j4130_publicationInfo a np:PublicationInfo . } dgn-np:NP822240.RAyprcZlxFJmk3fc6P2pBI2YUwLQk_mopxTt3KVNF04j4130_assertion { miriam-gene:2000 a ncit:C16612 . lld:C0175697 a ncit:C7057 . dgn-gda:DGNe602860f1afdc6b4e0254561476d37aa sio:SIO_000628 miriam-gene:2000, lld:C0175697; a sio:SIO_001121 . } dgn-np:NP822240.RAyprcZlxFJmk3fc6P2pBI2YUwLQk_mopxTt3KVNF04j4130_provenance { dgn-np:NP822240.RAyprcZlxFJmk3fc6P2pBI2YUwLQk_mopxTt3KVNF04j4130_assertion dcterms:description "[Using a number of approaches: mouse embryonic fibroblasts (MEF) from wild-type (WT), beta-arrestins knockouts (KO), beta-arrestins 1 and 2 double KO, and MEFs with reconstituted WT beta-arrestins in the double KO cells, RNA interference (siRNA) specific knockdown of beta-arrestins, and overexpression of WT beta-arrestins, it was demonstrated that beta-arrestin 2 positively regulates LPS-induced ERK 1/2 activation and both beta-arrestins 1 and 2 negatively regulate LPS-induced NFkappaB activation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:17418896; prov:wasDerivedFrom dgn-void:befree-20140225; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP822240.RAyprcZlxFJmk3fc6P2pBI2YUwLQk_mopxTt3KVNF04j4130_publicationInfo { this: dcterms:created "2014-10-02T12:40:23+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetrdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v2.1.0.0" . dgn-void:disgenetrdf pav:version "v2.1.0" . }