@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP800281.RAyR9AYwxknf_VTUR1Tb0oQIJsHByRVSOV2cXmnKjoxfo> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP800281.RAyR9AYwxknf_VTUR1Tb0oQIJsHByRVSOV2cXmnKjoxfo130_head {
  this: np:hasAssertion dgn-np:NP800281.RAyR9AYwxknf_VTUR1Tb0oQIJsHByRVSOV2cXmnKjoxfo130_assertion;
    np:hasProvenance dgn-np:NP800281.RAyR9AYwxknf_VTUR1Tb0oQIJsHByRVSOV2cXmnKjoxfo130_provenance;
    np:hasPublicationInfo dgn-np:NP800281.RAyR9AYwxknf_VTUR1Tb0oQIJsHByRVSOV2cXmnKjoxfo130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP800281.RAyR9AYwxknf_VTUR1Tb0oQIJsHByRVSOV2cXmnKjoxfo130_assertion a np:Assertion .
  
  dgn-np:NP800281.RAyR9AYwxknf_VTUR1Tb0oQIJsHByRVSOV2cXmnKjoxfo130_provenance a np:Provenance .
  
  dgn-np:NP800281.RAyR9AYwxknf_VTUR1Tb0oQIJsHByRVSOV2cXmnKjoxfo130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP800281.RAyR9AYwxknf_VTUR1Tb0oQIJsHByRVSOV2cXmnKjoxfo130_assertion {
  miriam-gene:9734 a ncit:C16612 .
  
  lld:C0027796 a ncit:C7057 .
  
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    a sio:SIO_001121 .
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dgn-np:NP800281.RAyR9AYwxknf_VTUR1Tb0oQIJsHByRVSOV2cXmnKjoxfo130_provenance {
  dgn-np:NP800281.RAyR9AYwxknf_VTUR1Tb0oQIJsHByRVSOV2cXmnKjoxfo130_assertion dcterms:description
      "[We show here that in the rat brainstem nucleus raphe magnus, which is important for central mechanisms of chronic pain, persistent inflammatory and neuropathic pain epigenetically suppresses Gad2 (encoding glutamic acid decarboxylase 65 (GAD65)) transcription through histone deacetylase (HDAC)-mediated histone hypoacetylation, resulting in impaired γ-aminobutyric acid (GABA) synaptic inhibition.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:21983856;
    prov:wasDerivedFrom dgn-void:befree-20140225;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP800281.RAyR9AYwxknf_VTUR1Tb0oQIJsHByRVSOV2cXmnKjoxfo130_publicationInfo {
  this: dcterms:created "2014-10-02T12:40:11+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
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    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v2.1.0.0" .
  
  dgn-void:disgenetrdf pav:version "v2.1.0" .
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