sub:assertion {
d:DB00359 dv:ddi-interactor-in dr:DB00359_DB01124 .
d:DB01124 dv:ddi-interactor-in dr:DB00359_DB01124 .
dr:DB00359_DB01124 dct:identifier "drugbank_resource:DB00359_DB01124" ;
dct:title "DDI between Sulfadiazine and Tolbutamide - Tolbutamide and Sulfadiazine are strong CYP2C9 inhibitors and substrates. Decreased metabolism and clearance of both agents may occur during concomitant therapy. Consider alternate therpy or monitor for changes in the therapeutic and adverse effects of both agents if concomitant therapy is initiated, discontinued or dose(s) changed."@en ;
a dv:Drug-Drug-Interaction ;
rdfs:label "DDI between Sulfadiazine and Tolbutamide - Tolbutamide and Sulfadiazine are strong CYP2C9 inhibitors and substrates. Decreased metabolism and clearance of both agents may occur during concomitant therapy. Consider alternate therpy or monitor for changes in the therapeutic and adverse effects of both agents if concomitant therapy is initiated, discontinued or dose(s) changed. [drugbank_resource:DB00359_DB01124]"@en .
}