http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.Head http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE http://www.nanopub.org/nschema#hasAssertion http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.assertion http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE http://www.nanopub.org/nschema#hasProvenance http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.provenance http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE http://www.nanopub.org/nschema#hasPublicationInfo http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.pubinfo http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.assertion http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._1 http://semanticscience.org/resource/SIO_000053 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._2 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._1 http://semanticscience.org/resource/SIO_000053 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._3 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.org/obo/owl/SO#SO_0001148 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://sadiframework.org/ontologies/GMOD/RangedSequencePosition.owl#RangedSequencePosition http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._1 http://www.w3.org/2000/01/rdf-schema#comment Does not affect deacetylase activity. Abolishes CDK2-dependent phosphorylation. Inhibits cellular proliferation delay in the early metaphase to prevent chromosomal instability. Does not inhibit interaction with a cyclin E-CDK2 complex. Does not inhibit interaction with HDAC6 and ubiquitination. Inhibits cell adhesion and migration and neurite outgrowth. Inhibits deacetylase activity; when associated with A-372. http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._2 http://semanticscience.org/resource/SIO_000300 331 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://sadiframework.org/ontologies/GMOD/RangedSequencePosition.owl#StartPosition http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._3 http://semanticscience.org/resource/SIO_000300 331 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://sadiframework.org/ontologies/GMOD/RangedSequencePosition.owl#EndPosition http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._4 http://semanticscience.org/resource/SIO_000053 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._5 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._4 http://semanticscience.org/resource/SIO_000053 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._6 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.org/obo/owl/SO#SO_0001148 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://sadiframework.org/ontologies/GMOD/RangedSequencePosition.owl#RangedSequencePosition http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._4 http://www.w3.org/2000/01/rdf-schema#comment Abolishes CDK2-dependent phosphorylation. Inhibits interaction with a cyclin E-CDK2 complex. Reduces strongly histone deacetylation activity. http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._5 http://semanticscience.org/resource/SIO_000300 331 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://sadiframework.org/ontologies/GMOD/RangedSequencePosition.owl#StartPosition http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._6 http://semanticscience.org/resource/SIO_000300 331 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._6 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://sadiframework.org/ontologies/GMOD/RangedSequencePosition.owl#EndPosition http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._7 http://semanticscience.org/resource/SIO_000053 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._8 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._7 http://semanticscience.org/resource/SIO_000053 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._9 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._7 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.org/obo/owl/SO#SO_0001148 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._7 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://sadiframework.org/ontologies/GMOD/RangedSequencePosition.owl#RangedSequencePosition http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._7 http://www.w3.org/2000/01/rdf-schema#comment Abolishes CDK2-dependent phosphorylation. http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._8 http://semanticscience.org/resource/SIO_000300 331 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._8 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://sadiframework.org/ontologies/GMOD/RangedSequencePosition.owl#StartPosition http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._9 http://semanticscience.org/resource/SIO_000300 331 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._9 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://sadiframework.org/ontologies/GMOD/RangedSequencePosition.owl#EndPosition http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.assertion http://www.w3.org/2000/01/rdf-schema#comment Mutagenesis site occurs in NX_Q8IXJ6-2 at amino acids 331 - 331. http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.seqFeature http://purl.obolibrary.org/obo/#BFO_0000066 http://www.nextprot.org/db/search#NX_Q8IXJ6-2 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.seqFeature http://semanticscience.org/resource/SIO_000008 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._1 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.seqFeature http://semanticscience.org/resource/SIO_000008 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._4 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.seqFeature http://semanticscience.org/resource/SIO_000008 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._7 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.seqFeature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.org/obo/owl/SO#SO_000010 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.provenance http://www.nextprot.org/help/quality_criteria/gold http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/eco.owl#ECO_0000205 http://www.nextprot.org/help/quality_criteria/gold http://www.w3.org/2000/01/rdf-schema#label neXtProt gold http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._10 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.bioassayontology.org/bao#BAO_0002095 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._11 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/eco.owl#ECO_0000218 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._12 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.bioassayontology.org/bao#BAO_0002095 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._13 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/eco.owl#ECO_0000218 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._14 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.bioassayontology.org/bao#BAO_0002095 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._15 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/eco.owl#ECO_0000218 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.assertion http://purl.org/net/provenance/ns#usedData http://www.uniprot.org/uniprot/Q8IXJ6 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.assertion http://purl.org/ontology/wi/core#evidence http://www.nextprot.org/help/quality_criteria/gold http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.assertion http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/eco.owl#ECO_0000006 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.assertion http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/eco.owl#ECO_0000200 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._10 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._12 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE._14 http://www.nextprot.org/nanopubs#NX_Q8IXJ6-2_MUTAGEN_331_331.RAyFUkWCYkGafvRlLf_-jJ01Pe3PI6U69k6hL97xKHrYE.assertion 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