@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix Protein: . @prefix hgnc: . @prefix geneProductOf: . @prefix go: . @prefix pfh: . @prefix hasAgent: . @prefix species: . @prefix occursIn: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 geneProductOf: hgnc:7765; a Protein: . sub:_2 hasAgent: sub:_3; a go:0016301 . sub:_3 geneProductOf: pfh:MAPK%20Erk1%2F3%20Family; a Protein: . sub:_4 occursIn: species:9606; rdf:object sub:_2; rdf:predicate belv:decreases; rdf:subject sub:_1; a rdf:Statement . sub:assertion rdfs:label "p(HGNC:NF1) -| kin(p(PFH:\"MAPK Erk1/3 Family\"))" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_6; pav:version "1.4" . sub:_5 prov:value "Alternatively, Kit signaling may also activate JNK kinase, a MAP kinase activated in response to stress [35]. NF1, a GTPase activating protein, is considered to be involved in modulating Ras activation through Kit signaling [36]. NF1 deficiency that occurs in cases of neurofibromatosis may induce an increase in MAP kinase activity. Pathways with JAK/STAT or with Src family members may be involved in Kit signaling [33] (fig. 1). Some studies showed the association of JAK2 with Kit and also its activation by Kit signaling [37]. Other reports also indicated the increased activity of Lyn, a Src family member, by Kit signaling [38]."; prov:wasQuotedFrom pubmed:15583854 . sub:_6 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:15583854; prov:wasDerivedFrom beldoc:, sub:_5 . } sub:pubinfo { this: dct:created "2014-07-03T14:30:30.083+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }