sub:assertion { d:DB00656dv:ddi-interactor-indr:DB00656_DB01026 . d:DB01026dv:ddi-interactor-indr:DB00656_DB01026 . dr:DB00656_DB01026dct:identifier "drugbank_resource:DB00656_DB01026" ; dct:title "DDI between Trazodone and Ketoconazole - The CYP3A4 inhibitor, Ketoconazole, may increase Trazodone efficacy/toxicity by decreasing Trazodone metabolism and clearance. Consider alternate therapy or monitor for changes in Trazodone efficacy/toxicity if Ketoconazole is initiated, discontinued or dose changed."@en ; adv:Drug-Drug-Interaction ; rdfs:label "DDI between Trazodone and Ketoconazole - The CYP3A4 inhibitor, Ketoconazole, may increase Trazodone efficacy/toxicity by decreasing Trazodone metabolism and clearance. Consider alternate therapy or monitor for changes in Trazodone efficacy/toxicity if Ketoconazole is initiated, discontinued or dose changed. [drugbank_resource:DB00656_DB01026]"@en . }