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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAxYFMPRds-j54j0O4hnbtrhJSGGyMQ2gB_JP2XArP-uA#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAxYFMPRds-j54j0O4hnbtrhJSGGyMQ2gB_JP2XArP-uA#_6 http://www.w3.org/ns/prov#value 10-Hz train stimulation also caused changes in expression of a MEF2-driven luciferase reporter introduced into the fibers via an adenoviral construct (Wilkins et al., 2004). 5 h of repetitive stimulation (5-s duration 10-Hz trains every 50 s) followed by 19 h without stimulation caused luciferase activity in fiber culture extracts to approximately double compared with extracts from parallel unstimulated fiber cultures (Fig. 3 B). The same stimulation (5 h, followed by 19 h without stimulation) in the presence of the CaMK inhibitor KN-62 gave the same luciferase activity as control. 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