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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAxWd8FnpQqvS79ENMnZqtMtAwxlW8hklgKW5lsdTQfZw#_4 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAxWd8FnpQqvS79ENMnZqtMtAwxlW8hklgKW5lsdTQfZw#_3 http://www.w3.org/ns/prov#value SPINK5, encoding the putative multi-domain serine protease inhibitor LEKTI, was recently identified as the defective gene in the severe autosomal recessive ichthyosiform skin condition, Netherton syndrome (NS). Using monoclonal and polyclonal antibodies, we show that LEKTI is a marker of epithelial differentiation, strongly expressed in the granular and uppermost spinous layers of the epidermis, and in differentiated layers of stratified epithelia. http://www.tkuhn.ch/bel2nanopub/RAxWd8FnpQqvS79ENMnZqtMtAwxlW8hklgKW5lsdTQfZw#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/12915442 http://www.tkuhn.ch/bel2nanopub/RAxWd8FnpQqvS79ENMnZqtMtAwxlW8hklgKW5lsdTQfZw#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAxWd8FnpQqvS79ENMnZqtMtAwxlW8hklgKW5lsdTQfZw#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/12915442 http://www.tkuhn.ch/bel2nanopub/RAxWd8FnpQqvS79ENMnZqtMtAwxlW8hklgKW5lsdTQfZw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAxWd8FnpQqvS79ENMnZqtMtAwxlW8hklgKW5lsdTQfZw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAxWd8FnpQqvS79ENMnZqtMtAwxlW8hklgKW5lsdTQfZw#_3 http://www.tkuhn.ch/bel2nanopub/RAxWd8FnpQqvS79ENMnZqtMtAwxlW8hklgKW5lsdTQfZw#pubinfo http://www.tkuhn.ch/bel2nanopub/RAxWd8FnpQqvS79ENMnZqtMtAwxlW8hklgKW5lsdTQfZw http://purl.org/dc/terms/created 2014-07-03T14:32:06.680+02:00 http://www.tkuhn.ch/bel2nanopub/RAxWd8FnpQqvS79ENMnZqtMtAwxlW8hklgKW5lsdTQfZw http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAxWd8FnpQqvS79ENMnZqtMtAwxlW8hklgKW5lsdTQfZw http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234