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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAxScW7q-q-rfqWdqdOXsFSDl8A72TCquZ-1BA73qOIYc#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAxScW7q-q-rfqWdqdOXsFSDl8A72TCquZ-1BA73qOIYc#_3 http://www.w3.org/ns/prov#value Cytokines (e.g., TNF-alpha and several interleukins) and constituents of modified lipoproteins (e.g., lysophosphatidyl choline) enhance oxidative stress in endothelial cells, which in turn activates the NFKB signaling pathway. Activated NFkB migrates into the nucleus and induces the expression of numerous genes, including many pro-inflammatory genes such as P-Selectin, ICAM-1 and VCAM-1. http://www.tkuhn.ch/bel2nanopub/RAxScW7q-q-rfqWdqdOXsFSDl8A72TCquZ-1BA73qOIYc#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/21293192 http://www.tkuhn.ch/bel2nanopub/RAxScW7q-q-rfqWdqdOXsFSDl8A72TCquZ-1BA73qOIYc#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAxScW7q-q-rfqWdqdOXsFSDl8A72TCquZ-1BA73qOIYc#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/21293192 http://www.tkuhn.ch/bel2nanopub/RAxScW7q-q-rfqWdqdOXsFSDl8A72TCquZ-1BA73qOIYc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAxScW7q-q-rfqWdqdOXsFSDl8A72TCquZ-1BA73qOIYc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAxScW7q-q-rfqWdqdOXsFSDl8A72TCquZ-1BA73qOIYc#_3 http://www.tkuhn.ch/bel2nanopub/RAxScW7q-q-rfqWdqdOXsFSDl8A72TCquZ-1BA73qOIYc#pubinfo http://www.tkuhn.ch/bel2nanopub/RAxScW7q-q-rfqWdqdOXsFSDl8A72TCquZ-1BA73qOIYc http://purl.org/dc/terms/created 2014-07-03T14:30:55.455+02:00 http://www.tkuhn.ch/bel2nanopub/RAxScW7q-q-rfqWdqdOXsFSDl8A72TCquZ-1BA73qOIYc http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAxScW7q-q-rfqWdqdOXsFSDl8A72TCquZ-1BA73qOIYc http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234