@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAxPTxaIn6CvWGFxkI0JG7qVkmx2rng3KktiYj8nz07Xc
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAxPTxaIn6CvWGFxkI0JG7qVkmx2rng3KktiYj8nz07Xc#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix microRNA: <
http://purl.obolibrary.org/obo/SO_0000276
> .
@prefix obo: <
http://purl.obolibrary.org/obo/
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
geneProductOf:
hgnc:11621
;
a
Protein:
.
sub:_2
geneProductOf:
hgnc:31496
;
a
microRNA:
.
sub:_3
occursIn:
obo:CLO_0003704
,
species:9606
;
rdf:object
sub:_2
;
rdf:predicate
belv:increases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"p(HGNC:HNF1A) -> m(HGNC:MIR107)" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_5
;
pav:version
"20131211" .
sub:_4
prov:value
"To test this hypothesis, we performed an HNF1 silencing using several doses of specific siRNA targeting HNF1 in the HepG2 hepatocellular cell line, and we assayed the consequences on the miR-107 expression level. The silencing of HNF1 significantly correlated with the extinction of miR-107 in a dose-effect manner (Spearman r: 0.92; P 0.0001; Fig. 3C)" ;
prov:wasQuotedFrom
pubmed:18433021
.
sub:_5
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:18433021
;
prov:wasDerivedFrom
beldoc:
,
sub:_4
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:33:20.046+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}