@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix orcid: <https://orcid.org/> .
@prefix pico: <http://data.cochrane.org/ontologies/pico/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sciencelive: <https://w3id.org/sciencelive/o/terms/> .
@prefix sub1: <https://w3id.org/np/RAxHFsc7u5QDdKJuh1gz1Cuba-ixjwrMQSZE7ErpbId6k/> .
@prefix this: <https://w3id.org/np/RAxHFsc7u5QDdKJuh1gz1Cuba-ixjwrMQSZE7ErpbId6k> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

sub1:Head {
  this: np:hasAssertion sub1:assertion;
    np:hasProvenance sub1:provenance;
    np:hasPublicationInfo sub1:pubinfo;
    a np:Nanopublication .
}

sub1:assertion {
  sub1:comparatorGroup dcterms:description "Historical baseline temperatures / lower temperature regions" .
  
  sub1:effect-of-temperature-increase-on-antimicrobial-resistance-rates pico:comparatorGroup
      sub1:comparatorGroup;
    pico:interventionGroup sub1:interventionGroup;
    pico:outcomeGroup sub1:outcomeGroup;
    pico:population sub1:population;
    dcterms:description "Does increased ambient temperature lead to higher antimicrobial resistance rates in bacterial populations?";
    a pico:PICO, sciencelive:CausationResearchQuestion;
    rdfs:label "Effect of temperature increase on antimicrobial resistance rates" .
  
  sub1:interventionGroup dcterms:description "Exposure to increased ambient temperatures (climate change effect)" .
  
  sub1:outcomeGroup dcterms:description "Antimicrobial resistance rates: proportion of resistant isolates, resistance gene prevalence, minimum inhibitory concentrations" .
  
  sub1:population dcterms:description "Bacterial isolates from clinical and environmental surveillance in European countries" .
}

sub1:provenance {
  sub1:assertion prov:wasAttributedTo orcid:0000-0002-1784-2920 .
}

sub1:pubinfo {
  orcid:0000-0002-1784-2920 foaf:name "Anne Fouilloux" .
  
  this: dcterms:created "2026-02-01T14:04:04+00:00"^^xsd:dateTime;
    dcterms:creator orcid:0000-0002-1784-2920;
    dcterms:license <https://creativecommons.org/licenses/by/4.0/>;
    npx:introduces sub1:effect-of-temperature-increase-on-antimicrobial-resistance-rates;
    npx:wasCreatedAt <https://platform.sciencelive4all.org/>;
    rdfs:label "PICO Research Question: Effect of temperature increase on antimicrobial resistance rates";
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  sub1:sig npx:hasAlgorithm "RSA";
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    npx:hasSignatureTarget this:;
    npx:signedBy <https://w3id.org/np/RAIA9ECaN2ypOVvl4YeNjT6nbpwko9xMcctxB_uYscLG4/claude-ai-agent> .
}