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Monitor for changes in the therapeutic and adverse effects of nortriptyline if ritonavir if initiated, discontinued or dose changed. http://bio2rdf.org/drugbank_resource:DB00503_DB00540 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://bio2rdf.org/drugbank_vocabulary:Drug-Drug-Interaction http://bio2rdf.org/drugbank_resource:DB00503_DB00540 http://www.w3.org/2000/01/rdf-schema#label DDI between Ritonavir and Nortriptyline - Ritonavir may increase the effect and toxicity of the tricyclic antidepressant, nortriptyline, by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects of nortriptyline if ritonavir if initiated, discontinued or dose changed. 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