@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP833919.RAwuC305PXaIvahzY3rE5OUsEP954VJ-Bm6L_8C5BQr5U130_head { this: np:hasAssertion dgn-np:NP833919.RAwuC305PXaIvahzY3rE5OUsEP954VJ-Bm6L_8C5BQr5U130_assertion; np:hasProvenance dgn-np:NP833919.RAwuC305PXaIvahzY3rE5OUsEP954VJ-Bm6L_8C5BQr5U130_provenance; np:hasPublicationInfo dgn-np:NP833919.RAwuC305PXaIvahzY3rE5OUsEP954VJ-Bm6L_8C5BQr5U130_publicationInfo; a np:Nanopublication . dgn-np:NP833919.RAwuC305PXaIvahzY3rE5OUsEP954VJ-Bm6L_8C5BQr5U130_assertion a np:Assertion . dgn-np:NP833919.RAwuC305PXaIvahzY3rE5OUsEP954VJ-Bm6L_8C5BQr5U130_provenance a np:Provenance . dgn-np:NP833919.RAwuC305PXaIvahzY3rE5OUsEP954VJ-Bm6L_8C5BQr5U130_publicationInfo a np:PublicationInfo . } dgn-np:NP833919.RAwuC305PXaIvahzY3rE5OUsEP954VJ-Bm6L_8C5BQr5U130_assertion { miriam-gene:3480 a ncit:C16612 . lld:C2939419 a ncit:C7057 . dgn-gda:DGN4fdc732310dbb008176f23569ddbe5be sio:SIO_000628 miriam-gene:3480, lld:C2939419; a sio:SIO_001121 . } dgn-np:NP833919.RAwuC305PXaIvahzY3rE5OUsEP954VJ-Bm6L_8C5BQr5U130_provenance { dgn-np:NP833919.RAwuC305PXaIvahzY3rE5OUsEP954VJ-Bm6L_8C5BQr5U130_assertion dcterms:description "[In this study, using the human colon cancer cell line HCT116, we find that established HCT116/IGF1-R transfectants exhibit a more aggressive transformed phenotype than the parental cell line, as demonstrated by their higher proliferation rate in response to IGF1, higher degree of anchorage-independent growth, resistance to serum deprivation-induced apoptosis, and higher migratory capability in a monolayer `wounding assay.` When injected into nude mice, HCT116/IGF1-R transfectants were highly invasive and produced distant metastases, whereas the parental cell did not.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:14633695; prov:wasDerivedFrom dgn-void:befree-20140225; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP833919.RAwuC305PXaIvahzY3rE5OUsEP954VJ-Bm6L_8C5BQr5U130_publicationInfo { this: dcterms:created "2014-10-02T12:40:30+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetrdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v2.1.0.0" . dgn-void:disgenetrdf pav:version "v2.1.0" . }