. . . . . . . . . . . . "p(HGNC:CDKN1B) -| bp(GOBP:\"cell cycle\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "Although the precise mechanism for this growth-inhibitory effect remains elusive,TGF-B is able to prevent progression through the cell cycle first by inducing expression of the cyclin kinase inhibitors p15INK4b,27 p21CIP1,28 and p27KIP1,29 which block cyclin and cyclin-dependent kinases from phosphorylating the retinoblastoma protein (Rb), thus allowing the hypophosphorylated form of Rb to bind and sequester the E2F transcription factor, and second by directly suppressing c-myc expression." . . "Selventa" . . . . "2014-07-03T14:32:41.698+02:00"^^ . . .