sub:assertion { d:DB01026dv:ddi-interactor-indr:DB01026_DB06335 . d:DB06335dv:ddi-interactor-indr:DB01026_DB06335 . dr:DB01026_DB06335dct:identifier "drugbank_resource:DB01026_DB06335" ; dct:title "DDI between Ketoconazole and Saxagliptin - Ketoconazole is a strong inhibitor of CYP3A4/5 which increases exposure of saxagliptin. The exposure of the active metabolite, 5-hydroxy saxagliptin, also decreases. Decrease dose of saxagliptin to 2.5 mg per day."@en ; adv:Drug-Drug-Interaction ; rdfs:label "DDI between Ketoconazole and Saxagliptin - Ketoconazole is a strong inhibitor of CYP3A4/5 which increases exposure of saxagliptin. The exposure of the active metabolite, 5-hydroxy saxagliptin, also decreases. Decrease dose of saxagliptin to 2.5 mg per day. [drugbank_resource:DB01026_DB06335]"@en . }