@prefix dct: . @prefix ns1: . @prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix np: . @prefix dgn-gda: . @prefix dgn-void: . ns1:NP1411718.RAwBdFIvASYpDf1mvnra_w5HAaoxfykw3KPLd1CnJ9f4M130_head { this: np:hasAssertion ns1:NP1411718.RAwBdFIvASYpDf1mvnra_w5HAaoxfykw3KPLd1CnJ9f4M130_assertion; np:hasProvenance ns1:NP1411718.RAwBdFIvASYpDf1mvnra_w5HAaoxfykw3KPLd1CnJ9f4M130_provenance; np:hasPublicationInfo ns1:NP1411718.RAwBdFIvASYpDf1mvnra_w5HAaoxfykw3KPLd1CnJ9f4M130_publicationInfo; a np:Nanopublication . ns1:NP1411718.RAwBdFIvASYpDf1mvnra_w5HAaoxfykw3KPLd1CnJ9f4M130_assertion a np:Assertion . ns1:NP1411718.RAwBdFIvASYpDf1mvnra_w5HAaoxfykw3KPLd1CnJ9f4M130_provenance a np:Provenance . ns1:NP1411718.RAwBdFIvASYpDf1mvnra_w5HAaoxfykw3KPLd1CnJ9f4M130_publicationInfo a np:PublicationInfo . } ns1:NP1411718.RAwBdFIvASYpDf1mvnra_w5HAaoxfykw3KPLd1CnJ9f4M130_assertion { miriam-gene:6774 a ncit:C16612 . lld:C2931027 a ncit:C7057 . dgn-gda:DGN67e0c04a527db37a5bbdbd699055b95f sio:SIO_000628 miriam-gene:6774, lld:C2931027; a sio:SIO_001121 . } ns1:NP1411718.RAwBdFIvASYpDf1mvnra_w5HAaoxfykw3KPLd1CnJ9f4M130_provenance { ns1:NP1411718.RAwBdFIvASYpDf1mvnra_w5HAaoxfykw3KPLd1CnJ9f4M130_assertion dct:description "[Although one of these (Y704) has previously been shown to be involved in STAT3 activation from a truncated G-CSF-R derived from a patient with severe chronic neutropenia (SCN), this tyrosine is not required for STAT3 activation by the full-length G-CSF-R. To investigate possible alternative mechanisms of STAT3 activation, we generated a series of Ba/F3 cell transfectants expressing the wild-type G-CSF-R or mutant receptors that either completely lack tyrosines or retain just one of the four cytoplasmic tyrosines of the G-CSF-R. We show that, at saturating G-CSF concentrations, STAT3 activation from the full-length G-CSF-R is efficiently mediated by the C-terminal domain in a manner independent of receptor tyrosines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:9864153; prov:wasDerivedFrom dgn-void:befree-2016; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } ns1:NP1411718.RAwBdFIvASYpDf1mvnra_w5HAaoxfykw3KPLd1CnJ9f4M130_publicationInfo { this: dct:created "2016-05-13T12:52:26+02:00"^^xsd:dateTime; dct:rights ; dct:rightsHolder dgn-void:IBIGroup; dct:subject sio:SIO_000983; prv:usedData dgn-void:disgenetv3.0rdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v4.0.0.0" . dgn-void:disgenetv3.0rdf pav:version "v4.0.0" . }