@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP638075.RAw8q898SvYWQvNE5jJKpnQEQBE7gTexy612pg3KckUJM130_head { this: np:hasAssertion dgn-np:NP638075.RAw8q898SvYWQvNE5jJKpnQEQBE7gTexy612pg3KckUJM130_assertion; np:hasProvenance dgn-np:NP638075.RAw8q898SvYWQvNE5jJKpnQEQBE7gTexy612pg3KckUJM130_provenance; np:hasPublicationInfo dgn-np:NP638075.RAw8q898SvYWQvNE5jJKpnQEQBE7gTexy612pg3KckUJM130_publicationInfo; a np:Nanopublication . dgn-np:NP638075.RAw8q898SvYWQvNE5jJKpnQEQBE7gTexy612pg3KckUJM130_assertion a np:Assertion . dgn-np:NP638075.RAw8q898SvYWQvNE5jJKpnQEQBE7gTexy612pg3KckUJM130_provenance a np:Provenance . dgn-np:NP638075.RAw8q898SvYWQvNE5jJKpnQEQBE7gTexy612pg3KckUJM130_publicationInfo a np:PublicationInfo . } dgn-np:NP638075.RAw8q898SvYWQvNE5jJKpnQEQBE7gTexy612pg3KckUJM130_assertion { miriam-gene:6426 a ncit:C16612 . lld:C3495537 a ncit:C7057 . dgn-gda:DGN75f2d4c01fdd03524624277838b7f89c sio:SIO_000628 miriam-gene:6426, lld:C3495537; a sio:SIO_001121 . } dgn-np:NP638075.RAw8q898SvYWQvNE5jJKpnQEQBE7gTexy612pg3KckUJM130_provenance { dgn-np:NP638075.RAw8q898SvYWQvNE5jJKpnQEQBE7gTexy612pg3KckUJM130_assertion dcterms:description "[Human immunodeficiency virus type 1 (HIV-1) Nef activation of p21-activated kinase 2 (PAK-2) was recapitulated in a cell-free system consisting of in vitro-transcribed RNA, rabbit reticulocyte lysate, and microsomal membranes on the basis of the following observations: (i) Nef associated with a kinase endogenous to the rabbit reticulocyte lysate that was identified as PAK-2, (ii) Nef-associated kinase activity was detected with Nefs from HIV-1(SF2), HIV-1(YU2), and SIV(mac239), (iii) kinase activation was not detected with a myristoylation-defective Nef (HIV-1(SF2)NefG2A) or with a Nef defective in PAK-2 activation but fully competent in other Nef functions (HIV-1(SF2)NefF195I), and (iv) Nef-associated kinase activation required activated endogenous p21 GTPases (Rac1 or Cdc42).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:16188976; prov:wasDerivedFrom dgn-void:befree-20140225; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP638075.RAw8q898SvYWQvNE5jJKpnQEQBE7gTexy612pg3KckUJM130_publicationInfo { this: dcterms:created "2014-10-02T12:38:25+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetrdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v2.1.0.0" . dgn-void:disgenetrdf pav:version "v2.1.0" . }