@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP287921.RAvxsGQ21aH4FUscaFF3-spzbb7S9OrGUcjVEoJh4Bpr0130_head { this: np:hasAssertion dgn-np:NP287921.RAvxsGQ21aH4FUscaFF3-spzbb7S9OrGUcjVEoJh4Bpr0130_assertion; np:hasProvenance dgn-np:NP287921.RAvxsGQ21aH4FUscaFF3-spzbb7S9OrGUcjVEoJh4Bpr0130_provenance; np:hasPublicationInfo dgn-np:NP287921.RAvxsGQ21aH4FUscaFF3-spzbb7S9OrGUcjVEoJh4Bpr0130_publicationInfo; a np:Nanopublication . dgn-np:NP287921.RAvxsGQ21aH4FUscaFF3-spzbb7S9OrGUcjVEoJh4Bpr0130_assertion a np:Assertion . dgn-np:NP287921.RAvxsGQ21aH4FUscaFF3-spzbb7S9OrGUcjVEoJh4Bpr0130_provenance a np:Provenance . dgn-np:NP287921.RAvxsGQ21aH4FUscaFF3-spzbb7S9OrGUcjVEoJh4Bpr0130_publicationInfo a np:PublicationInfo . } dgn-np:NP287921.RAvxsGQ21aH4FUscaFF3-spzbb7S9OrGUcjVEoJh4Bpr0130_assertion { miriam-gene:894 a ncit:C16612 . lld:C0021670 a ncit:C7057 . dgn-gda:DGN89449c72f61a15b46bacd61c1213e359 sio:SIO_000628 miriam-gene:894, lld:C0021670; a sio:SIO_001121 . } dgn-np:NP287921.RAvxsGQ21aH4FUscaFF3-spzbb7S9OrGUcjVEoJh4Bpr0130_provenance { dgn-np:NP287921.RAvxsGQ21aH4FUscaFF3-spzbb7S9OrGUcjVEoJh4Bpr0130_assertion dcterms:description "[1) Despite their common T-antigen-derived origins, MIN6 and BTC3 cells display markedly different G1/S expression profiles; 2) despite their common radiation origins, RINm5F and INS1 cells display striking differences in cell cycle protein profiles; 3) phosphorylation of pRb is absent in INS1 and RINm5F cells; 4) cyclin D2 is absent in RINm5F and BTC3 cells and therefore apparently dispensable for their proliferation; 5) every cell cycle inhibitor is upregulated, presumably in a futile attempt to halt proliferation; 6) among the G1/S proteome members, seven are pro-proliferation molecules: cyclin-dependent kinase-1, -2, -4, and -6 and cyclins A, E, and D3; and 7) overexpression of the combination of these seven converts arrested proliferation rates in primary rat beta-cells to those in insulinoma cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:18650366; prov:wasDerivedFrom dgn-void:befree-20150227; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-20150227 pav:importedOn "2015-02-27"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP287921.RAvxsGQ21aH4FUscaFF3-spzbb7S9OrGUcjVEoJh4Bpr0130_publicationInfo { this: dcterms:created "2015-08-25T14:40:24+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetv3.0rdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v3.0.0.0" . dgn-void:disgenetv3.0rdf pav:version "v3.0.0" . }