sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_8 ; pav:version "20131211" . sub:_7prov:value "c-H-Ras-induced survivin was expressed constitutively and independent of cell cycle progression or proliferation. Compromising Ras-stimulated PI3-K activity and MEK1 by chemicals abolished survivin expression and was associated with apoptotic cell death. Upregulation of survivin appeared to be an important activity of c-H-Ras oncoprotein, since cotransfection of a survivin-antisense construct into c-myc/c-H-ras-transfected primary rat embryo cells resulted in profound reduction of transformed clones." ; prov:wasQuotedFrompubmed:12833149 . sub:_8rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:12833149 ; prov:wasDerivedFrombeldoc: , sub:_7 . }