sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_3 ;
    pav:version "20131211" .
  sub:_2 prov:value "Our first goal was to determine whether repetitive nicotine exposure may affect the physiology of normal bronchial epithelial cells (NHBE). These cells were therefore grown in EGF and hydrocortisone depleted BEGM medium for 24 h before being exposed to 1, 50, 100 or 500 ?M nicotine daily during a week. After this time, we observed that the addition of doses of nicotine above 50 ?M induced cell growth arrest and development of a neuronal-like phenotype characterized by the protrusion of cell filopodia in a dose dependent manner" ;
    prov:wasQuotedFrom pubmed:18262213 .
  sub:_3 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:18262213 ;
    prov:wasDerivedFrom beldoc: , sub:_2 .
}