@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP744200.RAuIFK889S9fOZ5bI0yK83pwc5cbK7LmPcNpGIIfLsfdk> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP744200.RAuIFK889S9fOZ5bI0yK83pwc5cbK7LmPcNpGIIfLsfdk130_head {
  this: np:hasAssertion dgn-np:NP744200.RAuIFK889S9fOZ5bI0yK83pwc5cbK7LmPcNpGIIfLsfdk130_assertion;
    np:hasProvenance dgn-np:NP744200.RAuIFK889S9fOZ5bI0yK83pwc5cbK7LmPcNpGIIfLsfdk130_provenance;
    np:hasPublicationInfo dgn-np:NP744200.RAuIFK889S9fOZ5bI0yK83pwc5cbK7LmPcNpGIIfLsfdk130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP744200.RAuIFK889S9fOZ5bI0yK83pwc5cbK7LmPcNpGIIfLsfdk130_assertion a np:Assertion .
  
  dgn-np:NP744200.RAuIFK889S9fOZ5bI0yK83pwc5cbK7LmPcNpGIIfLsfdk130_provenance a np:Provenance .
  
  dgn-np:NP744200.RAuIFK889S9fOZ5bI0yK83pwc5cbK7LmPcNpGIIfLsfdk130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP744200.RAuIFK889S9fOZ5bI0yK83pwc5cbK7LmPcNpGIIfLsfdk130_assertion {
  miriam-gene:19 a ncit:C16612 .
  
  lld:C1868682 a ncit:C7057 .
  
  dgn-gda:DGN267416eae034c10b76c8a3faaf01b1cc sio:SIO_000628 miriam-gene:19, lld:C1868682;
    a sio:SIO_001121 .
}

dgn-np:NP744200.RAuIFK889S9fOZ5bI0yK83pwc5cbK7LmPcNpGIIfLsfdk130_provenance {
  dgn-np:NP744200.RAuIFK889S9fOZ5bI0yK83pwc5cbK7LmPcNpGIIfLsfdk130_assertion dcterms:description
      "[As compared with control vector Caco-2-H cells, Caco-2-T and Caco-2-MT cells displayed: (a) an enhanced tumorigenicity in nude mice; (b) a 4-fold increase in the level of PKC-alpha mRNA which was not due to enhanced mRNA stability and was mediated through a PKC-independent pathway since it persisted after PKC depletion; (c) increased PKC-alpha immunoreactive protein content (3-fold), total PKC catalytic activity (3.5-fold), and total cell number of [3H]phorbol-12,13-dibutyrate binding sites (4-fold); and (d) a 1.7-fold higher membrane-bound/total PKC activity ratio together with 1.8- and 1.5-fold increases in [3H]arachidonate- and [3H]myristate-labeled diacylglycerol levels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:8504416;
    prov:wasDerivedFrom dgn-void:befree-20140225;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP744200.RAuIFK889S9fOZ5bI0yK83pwc5cbK7LmPcNpGIIfLsfdk130_publicationInfo {
  this: dcterms:created "2014-10-02T12:39:31+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v2.1.0.0" .
  
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}