. . . . . . . . "Loss of endoproteolytic cleavage. Reduces production of amyloid beta in APP processing. Disassembly of the N-cadherin/PS1 complex at the cell surface. Impairs CDH2 processing." . "327"^^ . . "327"^^ . . . . . . "Abolishes gamma-secretase activity. Reduces production of amyloid beta in APP processing. Accumulation of full-length PS1. Loss of binding of transition state analog gamma-secretase inhibitor." . "327"^^ . . "327"^^ . . . . . . "No effect on caspase cleavage." . "327"^^ . . "327"^^ . . "Mutagenesis site occurs in NX_P49768-6 at amino acids 327 - 327." . . . . . . . "neXtProt gold" . . . . . . . . . . . . . . . . . "2014-09-19T00:00:00.0Z"^^ . . . "neXtProt database" . "CALIPHO project" . . . . . "1" . . . . . . .