http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_head http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_assertion http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_provenance http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_assertion http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Assertion http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_provenance http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Provenance http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_publicationInfo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#PublicationInfo http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_assertion http://identifiers.org/ncbigene/84630 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612 http://linkedlifedata.com/resource/umls/id/C0233794 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7057 http://rdf.disgenet.org/resource/gda/DGN4b11dde006c5af47836536ff1cf79da7 http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/84630 http://rdf.disgenet.org/resource/gda/DGN4b11dde006c5af47836536ff1cf79da7 http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0233794 http://rdf.disgenet.org/resource/gda/DGN4b11dde006c5af47836536ff1cf79da7 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001121 http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_provenance http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_assertion http://purl.org/dc/terms/description [TTBK1-Tg mice show significant age-dependent memory impairment as determined by radial arm water maze test, which is associated with enhancement of tau and neurofilament phosphorylation, increased levels of p25 and p35, both activators of cyclin-dependent protein kinase 5 (CDK5), enhanced calpain I activity, and reduced levels of hippocampal NMDA receptor types 2B (NR2B) and D. Enhanced CDK5/p35 complex formation is strongly correlated with dissociation of F-actin from p35, suggesting the inhibitory mechanism of CDK5/p35 complex formation by F-actin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/19118186 http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v3.0.0/void/befree-20150227 http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v3.0.0/void/befree-20150227 http://purl.org/pav/importedOn 2015-02-27 http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://purl.org/dc/terms/created 2015-08-25T14:47:24+02:00 http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v3.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v3.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP956901.RAu5qv2aKzEv2ZYC--pbPsqrVlzp8HcxGmgfyYHT47W7o http://purl.org/pav/version v3.0.0.0 http://rdf.disgenet.org/v3.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v3.0.0