. . . . . . . . . . . . "[The accumulation of deletions in HEp-2 and HEL cells could not be attributed to the fusion of the TK gene with the alpha 4 gene promoter, to the presence of an origin of DNA replication, or to overexpression of any of the genes whose domain is contained entirely in the HSV-1 Bam HI N fragment; these conclusions are based on the observations that deletions did not accumulate in HEL or HEp-2 cells infected with recombinant R315, containing BamHI N inserted in an inverted orientation, or with recombinant R314, carrying an alpha 4-TK chimera constructed by insertion of the HSV-1 BamHI Z fragment into the BglII cleavage site in the TK gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2014-02-25"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2014-10-02T12:37:48+02:00"^^ . . . . . . . . . . . "v2.1.0.0" . "v2.1.0" .