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The OECD Omics Reporting Framework (OORF) was developed to increase transparency in the reporting of Omics data used in regulatory toxicology, and aid regulatory uptake while remaining sufficiently flexible to allow technologies to evolve. It is a harmonized combination of the Transcriptomics Reporting Framework (TRF) and a Metabolomics Reporting Framework (MRF), with four types of reporting modules:
(i) The Study Summary Reporting Module (SSRM) provides a high-level overview of the regulatory toxicology and Omics experiment,
(ii) The Toxicology Experiment Reporting Module (TERM) reports the key descriptors of the in vivo or in vitro toxicology study,
(iii) Data Acquisition and Processing Reporting Modules (DAPRM) report descriptions of the Omics assays, data acquisition and associated data,
(iv) Data Analysis Reporting Modules (DARM) describe the statistical analysis that has been undertaken in the Omics study.
Guidance documents describe each of the reporting modules in detail alongside associated templates are available via the website.
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