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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAspMnnrmN39VKEAMokrWy-mZE3mXHlVWe3P8qish1aqw#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAspMnnrmN39VKEAMokrWy-mZE3mXHlVWe3P8qish1aqw#_3 http://www.w3.org/ns/prov#value We next examined the possible effects of anticancer drugs on the expression of Hsp70 and HspBP1 in tumor cells. All three anticancer drugs examined (vincristine, paclitaxel, and etoposide) induced a ~2.0 - 2.5-fold increase in the amount of HspBP1 in HeLa S3 cells (representative of tumor cells with a low HspBP1/Hsp70 molar ratio) as well as in MKN1 cells (representative of tumor cells with a high HspBP1/Hsp70 molar ratio), with the highest expression levels being apparent between 6 and 24 h after the onset of drug treatment (Fig. 5). In contrast, the expression level of Hsp70 was not substantially affected by exposure of the tumor cells to these anticancer drugs for up to 24 h. http://www.tkuhn.ch/bel2nanopub/RAspMnnrmN39VKEAMokrWy-mZE3mXHlVWe3P8qish1aqw#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/17855353 http://www.tkuhn.ch/bel2nanopub/RAspMnnrmN39VKEAMokrWy-mZE3mXHlVWe3P8qish1aqw#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAspMnnrmN39VKEAMokrWy-mZE3mXHlVWe3P8qish1aqw#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/17855353 http://www.tkuhn.ch/bel2nanopub/RAspMnnrmN39VKEAMokrWy-mZE3mXHlVWe3P8qish1aqw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAspMnnrmN39VKEAMokrWy-mZE3mXHlVWe3P8qish1aqw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAspMnnrmN39VKEAMokrWy-mZE3mXHlVWe3P8qish1aqw#_3 http://www.tkuhn.ch/bel2nanopub/RAspMnnrmN39VKEAMokrWy-mZE3mXHlVWe3P8qish1aqw#pubinfo http://www.tkuhn.ch/bel2nanopub/RAspMnnrmN39VKEAMokrWy-mZE3mXHlVWe3P8qish1aqw http://purl.org/dc/terms/created 2014-07-03T14:30:51.612+02:00 http://www.tkuhn.ch/bel2nanopub/RAspMnnrmN39VKEAMokrWy-mZE3mXHlVWe3P8qish1aqw http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAspMnnrmN39VKEAMokrWy-mZE3mXHlVWe3P8qish1aqw http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234