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[Among 21 non-HLA susceptibility loci for PBC identified in GWASs of individuals of European descent, three loci (IL7R, IKZF3, and CD80) showed significant associations (combined p�= 3.66�� 10(-8), 3.66�� 10(-9), and 3.04�� 10(-9), respectively) and STAT4 and NFKB1 loci showed suggestive association with PBC (combined p = 1.11�� 10(-6) and 1.42�� 10(-7), respectively) in the Japanese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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