@prefix this: <
http://bio2rdf.org/drugbank:DB00270_nanopub.RAsTTagmuPXoh1ju9qhtIsQ1b2pDJDuuA4zl3YnTRMaLw
> .
@prefix sub: <
http://bio2rdf.org/drugbank:DB00270_nanopub.RAsTTagmuPXoh1ju9qhtIsQ1b2pDJDuuA4zl3YnTRMaLw#
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix orcid: <
http://orcid.org/
> .
@prefix codebase: <
https://github.com/tkuhn/bio2rdf2nanopub
> .
@prefix version: <
https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349
> .
@prefix instance: <
https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB
> .
@prefix process: <
https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix v: <
http://bio2rdf.org/bio2rdf_vocabulary:
> .
@prefix d: <
http://bio2rdf.org/drugbank:
> .
@prefix dv: <
http://bio2rdf.org/drugbank_vocabulary:
> .
@prefix dr: <
http://bio2rdf.org/drugbank_resource:
> .
@prefix dcat: <
http://www.w3.org/ns/dcat#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:publicationInfo
;
a
np:Nanopublication
.
}
sub:assertion
{
d:DB00270
v:identifier
"DB00270" ;
v:namespace
"drugbank" ;
v:uri
"http://bio2rdf.org/drugbank:DB00270" ;
v:x-identifiers.org
<
http://identifiers.org/drugbank/DB00270
> ;
dv:drugbank-id
"APRD00298" , "DB00270" ;
dv:x-ahfs
<
http://bio2rdf.org/ahfs:24:28.08
> ;
dv:x-atc
<
http://bio2rdf.org/atc:C08CA03
> ;
dv:x-cas
<
http://bio2rdf.org/cas:75695-93-1
> ;
dv:x-chemspider
<
http://bio2rdf.org/chemspider:3652
> ;
dv:x-kegg
<
http://bio2rdf.org/kegg:D00349
> ;
dv:x-ndc
<
http://bio2rdf.org/ndc:0173-0784-01
> ;
dv:x-pharmgkb
<
http://bio2rdf.org/pharmgkb:PA450131
> ;
dv:x-pubchemcompound
<
http://bio2rdf.org/pubchem.compound:3784
> ;
dv:x-pubchemsubstance
<
http://bio2rdf.org/pubchem.substance:46505034
> ;
dv:x-wikipedia
<
http://bio2rdf.org/wikipedia:Isradipine
> ;
dct:description
"Isradipine belongs to the dihydropyridine (DHP) class of calcium channel blockers (CCBs), the most widely used class of CCBs. It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blocking agent of the DHP class. Isradipine binds to calcium channels with high affinity and specificity and inhibits calcium flux into cardiac and arterial smooth muscle cells. It exhibits greater selectivity towards arterial smooth muscle cells owing to alternative splicing of the alpha-1 subunit of the channel and increased prevalence of inactive channels in smooth muscle cells. Isradipine may be used to treat mild to moderate essential hypertension."@en ;
dct:identifier
"drugbank:DB00270" ;
dct:title
"Isradipine"@en ;
a
dv:Drug
;
rdfs:label
"Isradipine [drugbank:DB00270]"@en ;
rdfs:seeAlso
<
http://www.drugbank.ca/drugs/DB00270
> , <
http://www.drugs.com/cdi/isradipine.html
> , <
http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/dyn1152.shtml
> , <
http://www.rxlist.com/cgi/generic2/israd.htm
> .
}
sub:provenance
{
sub:assertion
prov:wasDerivedFrom
<
http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz
> .
dr:bio2rdf.dataset.drugbank.R3
dcat:distribution
<
http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz
> .
<
http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz
>
dct:created
"2015-01-09T17:00:50-05:00"^^
xsd:dateTime
;
prov:wasDerivedFrom
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00
> .
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00
>
pav:retrievedOn
"2014-11-12T07:57:03-05:00"^^
xsd:dateTime
;
prov:wasDerivedFrom
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip
> .
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip
>
prov:wasAttributedTo
<
http://drugbank.ca
> .
}
sub:publicationInfo
{
sub:signature.MCwCFBcB-2ENSZMS
npx:hasPublicKey
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npx:hasSignature
"MCwCFBcB+2ENSZMS+3mNXOWhmBla9Ei+AhRcRshJPzjvdk9gdSDCPiUy2IP8NA==" ;
npx:signedBy
instance:
.
this:
dct:created
"2018-03-30T11:10:54.105+02:00"^^
xsd:dateTime
;
dct:license
<
https://creativecommons.org/licenses/by-nc/4.0/
> ;
npx:hasSignatureElement
sub:signature.MCwCFBcB-2ENSZMS
;
prov:wasGeneratedBy
process:
.
instance:
prov:specializationOf
codebase:
;
prov:wasAttributedTo
orcid:0000-0002-1267-0234
.
process:
dct:identifier
"7720f136-841b-4851-a6e4-ad20a409a475" ;
prov:used
version:
;
prov:wasAssociatedWith
instance:
;
prov:wasStartedBy
orcid:0000-0002-1267-0234
.
version:
dct:isVersionOf
codebase:
;
pav:version
"eda7951a5f6c622c5d2132f50c3093138484a349" ;
prov:wasAttributedTo
orcid:0000-0002-1267-0234
.
}