http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#Head http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#assertion http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#provenance http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#pubinfo http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#assertion http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_2 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0005525 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_2 http://purl.obolibrary.org/obo/RO_0002204 http://rgd.mcw.edu/rgdweb/report/gene/main.html?id=619921 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_3 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_4 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_4 http://purl.obolibrary.org/obo/RO_0002204 http://rgd.mcw.edu/rgdweb/report/gene/main.html?id=3590 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/CL_0000187 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/UBERON_0004237 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10116 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_3 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/directlyIncreases http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_1 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#assertion http://www.w3.org/2000/01/rdf-schema#label gtp(p(RGD:Rhoa)) => kin(p(RGD:Rock2)) http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_7 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_6 http://www.w3.org/ns/prov#value FIG. 2. Scheme of regulation of the small GTPase RhoA. In the resting state, RhoA GDP exists in the cytosol with its prenylated, hydrophobic tail buried within its partner, GDP dissociation inhibitor (RhoGDI). Activation of receptors coupled to certain trimeric G proteins (Galpha q, Galpha12,13) and receptor Tyr kinases leads, through activity of guanine nucleotide exchange factors (GEFs), to the exchange of GTP for GDP on RhoA. RhoGDI dissociates and RhoA GTP associates with the membrane where it interacts with Rho-kinase (ROK) to initiate signaling cascades. Rho GTPase activating proteins (RhoGAPs) catalyze hydrolysis of GTP bound to RhoA and RhoA GDP reassociates with RhoAGDI. http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/14506307 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/14506307 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#_6 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI#pubinfo http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI http://purl.org/dc/terms/created 2014-07-03T14:32:09.362+02:00 http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAsQE5tuAwuk_s_fJC4Je3MgVTJA01XX8SbtfYQcKusOI http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234