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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAsITQhNhAWdDe3EUw1uOEgeFQ7i1lifIBI7kFOB17vug#_5 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAsITQhNhAWdDe3EUw1uOEgeFQ7i1lifIBI7kFOB17vug#_4 http://www.w3.org/ns/prov#value Whereas the Nrf2 level was very low in the cells cotransfected with WT Keap1, treatment of cells with the proteasome inhibitor MG132 stabilized the Nrf2 protein (Fig. 3A, lanes 1 and 2). The Nrf2 level in cells cotransfected with the R272C mutant was very high and was not induced effectively by MG132 (Fig. 3A, lanes 3 and 4). These results indicate that the R272C mutant impaired Nrf2 degradation. http://www.tkuhn.ch/bel2nanopub/RAsITQhNhAWdDe3EUw1uOEgeFQ7i1lifIBI7kFOB17vug#_4 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/18316592 http://www.tkuhn.ch/bel2nanopub/RAsITQhNhAWdDe3EUw1uOEgeFQ7i1lifIBI7kFOB17vug#_5 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAsITQhNhAWdDe3EUw1uOEgeFQ7i1lifIBI7kFOB17vug#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/18316592 http://www.tkuhn.ch/bel2nanopub/RAsITQhNhAWdDe3EUw1uOEgeFQ7i1lifIBI7kFOB17vug#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAsITQhNhAWdDe3EUw1uOEgeFQ7i1lifIBI7kFOB17vug#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAsITQhNhAWdDe3EUw1uOEgeFQ7i1lifIBI7kFOB17vug#_4 http://www.tkuhn.ch/bel2nanopub/RAsITQhNhAWdDe3EUw1uOEgeFQ7i1lifIBI7kFOB17vug#pubinfo http://www.tkuhn.ch/bel2nanopub/RAsITQhNhAWdDe3EUw1uOEgeFQ7i1lifIBI7kFOB17vug http://purl.org/dc/terms/created 2014-07-03T14:33:18.526+02:00 http://www.tkuhn.ch/bel2nanopub/RAsITQhNhAWdDe3EUw1uOEgeFQ7i1lifIBI7kFOB17vug http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAsITQhNhAWdDe3EUw1uOEgeFQ7i1lifIBI7kFOB17vug http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234