[ {
  "@graph" : [ {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ",
    "@type" : [ "http://www.nanopub.org/nschema#Nanopublication" ],
    "http://www.nanopub.org/nschema#hasAssertion" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#assertion"
    } ],
    "http://www.nanopub.org/nschema#hasProvenance" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#provenance"
    } ],
    "http://www.nanopub.org/nschema#hasPublicationInfo" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#pubinfo"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#Head"
}, {
  "@graph" : [ {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_1",
    "@type" : [ "http://amigo.geneontology.org/amigo/term/GO:0016301" ],
    "http://semanticscience.org/resource/SIO_000139" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_2"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_2",
    "@type" : [ "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080" ],
    "http://purl.obolibrary.org/obo/RO_0002204" : [ {
      "@id" : "http://resource.belframework.org/belframework/20131211/namespace/selventa-protein-families/AKT%20Family"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_3",
    "@type" : [ "http://amigo.geneontology.org/amigo/term/GO:0003824" ],
    "http://semanticscience.org/resource/SIO_000139" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_4"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_4",
    "@type" : [ "http://amigo.geneontology.org/amigo/term/GO:0043234" ],
    "http://purl.obolibrary.org/obo/BFO_0000051" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_5"
    }, {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_6"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_5",
    "@type" : [ "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080" ],
    "http://purl.obolibrary.org/obo/RO_0002204" : [ {
      "@id" : "http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=12362"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_6",
    "@type" : [ "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080" ],
    "http://purl.obolibrary.org/obo/RO_0002204" : [ {
      "@id" : "http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=12363"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_7",
    "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ],
    "http://purl.obolibrary.org/obo/BFO_0000066" : [ {
      "@id" : "http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_3"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ {
      "@id" : "http://www.selventa.com/vocabulary/decreases"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_1"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#assertion",
    "http://www.w3.org/2000/01/rdf-schema#label" : [ {
      "@value" : "kin(p(SFAM:\"AKT Family\")) -| cat(complex(p(HGNC:TSC1),p(HGNC:TSC2)))"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#assertion"
}, {
  "@graph" : [ {
    "@id" : "http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel",
    "http://purl.org/dc/elements/1.1/description" : [ {
      "@value" : "Approximately 61,000 statements."
    } ],
    "http://purl.org/dc/elements/1.1/rights" : [ {
      "@value" : "Copyright (c) 2011-2012, Selventa. All rights reserved."
    } ],
    "http://purl.org/dc/elements/1.1/title" : [ {
      "@value" : "BEL Framework Large Corpus Document"
    } ],
    "http://purl.org/pav/authoredBy" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_9"
    } ],
    "http://purl.org/pav/version" : [ {
      "@value" : "20131211"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_8",
    "http://www.w3.org/ns/prov#value" : [ {
      "@value" : "Class I PI3K, a heterodimer consisting of a regulatory and a catalytic subunit, is a negative regulator of autophagy that is activated by the insulin receptor and the insulin receptor substrate proteins. Activated class I PI3K mainly uses PtdIns(4,5)P2 as substrate to yield PtdIns(3,4,5)P3 at the plasma membrane, which increases membrane recruitment of both PKB/Akt and its activator phosphoinositide- dependent protein kinase 1, leading to the activation of PKB/Akt, a downstream negative regulator of autophagy. Activated PKB/Akt further activates mTOR through inhibiting a downstream protein complex, the tuberous sclerosis complex 1/2, that represses the small G protein Rheb, causing inhibition of autophagy."
    } ],
    "http://www.w3.org/ns/prov#wasQuotedFrom" : [ {
      "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/21709535"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_9",
    "http://www.w3.org/2000/01/rdf-schema#label" : [ {
      "@value" : "Selventa"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#assertion",
    "http://www.w3.org/ns/prov#hadPrimarySource" : [ {
      "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/21709535"
    } ],
    "http://www.w3.org/ns/prov#wasDerivedFrom" : [ {
      "@id" : "http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel"
    }, {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#_8"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#provenance"
}, {
  "@graph" : [ {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ",
    "http://purl.org/dc/terms/created" : [ {
      "@type" : "http://www.w3.org/2001/XMLSchema#dateTime",
      "@value" : "2014-07-03T14:33:41.570+02:00"
    } ],
    "http://purl.org/pav/createdBy" : [ {
      "@id" : "http://orcid.org/0000-0001-6818-334X"
    }, {
      "@id" : "http://orcid.org/0000-0002-1267-0234"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RAsCo6j2piUwtCpyOY7BCQaiiCwI9S8PLoooWJscKo-XQ#pubinfo"
} ]