http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA#head http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA http://www.nanopub.org/nschema#hasAssertion http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA#assertion http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA http://www.nanopub.org/nschema#hasProvenance http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA#provenance http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA http://www.nanopub.org/nschema#hasPublicationInfo http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA#publicationInfo http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA#assertion http://bio2rdf.org/drugbank:DB05237 http://bio2rdf.org/bio2rdf_vocabulary:identifier DB05237 http://bio2rdf.org/drugbank:DB05237 http://bio2rdf.org/bio2rdf_vocabulary:namespace drugbank http://bio2rdf.org/drugbank:DB05237 http://bio2rdf.org/bio2rdf_vocabulary:uri http://bio2rdf.org/drugbank:DB05237 http://bio2rdf.org/drugbank:DB05237 http://bio2rdf.org/bio2rdf_vocabulary:x-identifiers.org http://identifiers.org/drugbank/DB05237 http://bio2rdf.org/drugbank:DB05237 http://bio2rdf.org/drugbank_vocabulary:drugbank-id DB05237 http://bio2rdf.org/drugbank:DB05237 http://bio2rdf.org/drugbank_vocabulary:x-cas http://bio2rdf.org/cas: http://bio2rdf.org/drugbank:DB05237 http://bio2rdf.org/drugbank_vocabulary:x-uniprot http://bio2rdf.org/uniprot:P11226 http://bio2rdf.org/drugbank:DB05237 http://bio2rdf.org/drugbank_vocabulary:x-wikipedia http://bio2rdf.org/wikipedia:Mannose_binding_lectin http://bio2rdf.org/drugbank:DB05237 http://purl.org/dc/terms/description rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections in individuals with low levels of Mannose-Binding Lectin (MBL). Over 10 percent of the general population is estimated to be MBL-deficient. Natural MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three identical peptide chains of 32 kDa each. Although MBL can form several oligomeric forms, there are indications that dimers and trimers are not biologically active and at least a tetramer form is needed for activation of complement. http://bio2rdf.org/drugbank:DB05237 http://purl.org/dc/terms/identifier drugbank:DB05237 http://bio2rdf.org/drugbank:DB05237 http://purl.org/dc/terms/title rhMBL http://bio2rdf.org/drugbank:DB05237 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://bio2rdf.org/drugbank_vocabulary:Drug http://bio2rdf.org/drugbank:DB05237 http://www.w3.org/2000/01/rdf-schema#label rhMBL [drugbank:DB05237] http://bio2rdf.org/drugbank:DB05237 http://www.w3.org/2000/01/rdf-schema#seeAlso http://www.drugbank.ca/drugs/DB05237 http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA#provenance http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz http://bio2rdf.org/drugbank_resource:bio2rdf.dataset.drugbank.R3 http://www.w3.org/ns/dcat#distribution http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz http://purl.org/dc/terms/created 2015-01-09T17:00:50-05:00 http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz http://www.w3.org/ns/prov#wasDerivedFrom http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00 http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00 http://purl.org/pav/retrievedOn 2014-11-12T07:57:03-05:00 http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00 http://www.w3.org/ns/prov#wasDerivedFrom http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip http://www.w3.org/ns/prov#wasAttributedTo http://drugbank.ca http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA#publicationInfo http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA#signature.MC4CFQCUBPx3yx29 http://purl.org/nanopub/x/hasPublicKey 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 http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA#signature.MC4CFQCUBPx3yx29 http://purl.org/nanopub/x/hasSignature MC4CFQCUBPx3yx29JgSWlL+VJ8fpN4CPPQIVAIJ6gMLrG6zJTXuBA1F4QsbbtNX/ http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA#signature.MC4CFQCUBPx3yx29 http://purl.org/nanopub/x/signedBy https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA http://purl.org/dc/terms/created 2018-03-30T11:10:46.157+02:00 http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA http://purl.org/dc/terms/license https://creativecommons.org/licenses/by-nc/4.0/ http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA http://purl.org/nanopub/x/hasSignatureElement http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA#signature.MC4CFQCUBPx3yx29 http://bio2rdf.org/drugbank:DB05237_nanopub.RAs9VR-8p6912GXxVaw6_7oa78Eghcs08nsVK5CqQtauA http://www.w3.org/ns/prov#wasGeneratedBy https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475 https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB http://www.w3.org/ns/prov#specializationOf https://github.com/tkuhn/bio2rdf2nanopub https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB http://www.w3.org/ns/prov#wasAttributedTo http://orcid.org/0000-0002-1267-0234 https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475 http://purl.org/dc/terms/identifier 7720f136-841b-4851-a6e4-ad20a409a475 https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475 http://www.w3.org/ns/prov#used https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349 https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475 http://www.w3.org/ns/prov#wasAssociatedWith https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475 http://www.w3.org/ns/prov#wasStartedBy http://orcid.org/0000-0002-1267-0234 https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349 http://purl.org/dc/terms/isVersionOf https://github.com/tkuhn/bio2rdf2nanopub https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349 http://purl.org/pav/version eda7951a5f6c622c5d2132f50c3093138484a349 https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349 http://www.w3.org/ns/prov#wasAttributedTo http://orcid.org/0000-0002-1267-0234