@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP883149.RAs4pyH38Gi7KIthWniMPqngGInzrgUC2ZUc77cXvDxuc130_head { this: np:hasAssertion dgn-np:NP883149.RAs4pyH38Gi7KIthWniMPqngGInzrgUC2ZUc77cXvDxuc130_assertion; np:hasProvenance dgn-np:NP883149.RAs4pyH38Gi7KIthWniMPqngGInzrgUC2ZUc77cXvDxuc130_provenance; np:hasPublicationInfo dgn-np:NP883149.RAs4pyH38Gi7KIthWniMPqngGInzrgUC2ZUc77cXvDxuc130_publicationInfo; a np:Nanopublication . dgn-np:NP883149.RAs4pyH38Gi7KIthWniMPqngGInzrgUC2ZUc77cXvDxuc130_assertion a np:Assertion . dgn-np:NP883149.RAs4pyH38Gi7KIthWniMPqngGInzrgUC2ZUc77cXvDxuc130_provenance a np:Provenance . dgn-np:NP883149.RAs4pyH38Gi7KIthWniMPqngGInzrgUC2ZUc77cXvDxuc130_publicationInfo a np:PublicationInfo . } dgn-np:NP883149.RAs4pyH38Gi7KIthWniMPqngGInzrgUC2ZUc77cXvDxuc130_assertion { miriam-gene:1026 a ncit:C16612 . lld:C0006142 a ncit:C7057 . dgn-gda:DGN3561595e502a12e06d82ab54bf8b051f sio:SIO_000628 miriam-gene:1026, lld:C0006142; a sio:SIO_001121 . } dgn-np:NP883149.RAs4pyH38Gi7KIthWniMPqngGInzrgUC2ZUc77cXvDxuc130_provenance { dgn-np:NP883149.RAs4pyH38Gi7KIthWniMPqngGInzrgUC2ZUc77cXvDxuc130_assertion dcterms:description "[Strikingly, we found that silencing FLOT1 inhibited proliferation and tumorigenicity of breast cancer cells both in vitro and in vivo, which was further shown to be mechanistically associated with suppression of Akt activity, enhanced transcriptional activity of FOXO3a, upregulation of cyclin-dependent kinase inhibitor p21(Cip1) and p27(Kip1), and downregulation of the CDK regulator cyclin D1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:21447726; prov:wasDerivedFrom dgn-void:befree-2016; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP883149.RAs4pyH38Gi7KIthWniMPqngGInzrgUC2ZUc77cXvDxuc130_publicationInfo { this: dcterms:created "2016-05-13T12:48:24+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetv3.0rdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v4.0.0.0" . dgn-void:disgenetv3.0rdf pav:version "v4.0.0" . }