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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAs2E1n8JizZiLNjhgPc5GcZpAe6H_aaVP_Pifhizh6zQ#_4 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAs2E1n8JizZiLNjhgPc5GcZpAe6H_aaVP_Pifhizh6zQ#_3 http://www.w3.org/ns/prov#value Moreover, the critical residue threonine 845 (Thr845) within the activation loop of ASK1 was phosphorylated by ceramide (Figures 5A,S2). The increased phosphorylation of ASK1 Thr845 correlates with ASK1 activation.45,50 Therefore, ceramide caused ASK1 activation by inducing dephosphorylation at Ser83 and phosphorylation at Thr845. http://www.tkuhn.ch/bel2nanopub/RAs2E1n8JizZiLNjhgPc5GcZpAe6H_aaVP_Pifhizh6zQ#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/18270325 http://www.tkuhn.ch/bel2nanopub/RAs2E1n8JizZiLNjhgPc5GcZpAe6H_aaVP_Pifhizh6zQ#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAs2E1n8JizZiLNjhgPc5GcZpAe6H_aaVP_Pifhizh6zQ#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/18270325 http://www.tkuhn.ch/bel2nanopub/RAs2E1n8JizZiLNjhgPc5GcZpAe6H_aaVP_Pifhizh6zQ#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAs2E1n8JizZiLNjhgPc5GcZpAe6H_aaVP_Pifhizh6zQ#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAs2E1n8JizZiLNjhgPc5GcZpAe6H_aaVP_Pifhizh6zQ#_3 http://www.tkuhn.ch/bel2nanopub/RAs2E1n8JizZiLNjhgPc5GcZpAe6H_aaVP_Pifhizh6zQ#pubinfo http://www.tkuhn.ch/bel2nanopub/RAs2E1n8JizZiLNjhgPc5GcZpAe6H_aaVP_Pifhizh6zQ http://purl.org/dc/terms/created 2014-07-03T14:33:17.407+02:00 http://www.tkuhn.ch/bel2nanopub/RAs2E1n8JizZiLNjhgPc5GcZpAe6H_aaVP_Pifhizh6zQ http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAs2E1n8JizZiLNjhgPc5GcZpAe6H_aaVP_Pifhizh6zQ http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234