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p(MGI:Scarb1) -| p(MGI:Tnf)
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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As shown in Figure 1, LPS resulted in a strong induction of both TNF-? and IL-6. In the case of TNF-?, maximum concentrations were reached by 2 hours and were markedly higher in the SR-BI–null mice than in control mice (Figure 1A). In the case of IL-6, LPS-induced plasma concentrations reached nearly similar maximal levels in both SR-BI–null and control mice after 2 hours (Figure 1B). However, IL-6 levels in control mice returned to baseline levels after 8 hours, whereas the level of IL-6 in SR-BI–null mice remained elevated for 24 hours before dropping to baseline levels by 48 hours.
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Selventa
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