http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_head http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_assertion http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_provenance http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_assertion http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Assertion http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_provenance http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Provenance http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_publicationInfo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#PublicationInfo http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_assertion http://identifiers.org/ncbigene/50964 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612 http://linkedlifedata.com/resource/umls/id/C0029456 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7057 http://rdf.disgenet.org/resource/gda/DGN45ec1e834f4baf0922581c526120633c http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/50964 http://rdf.disgenet.org/resource/gda/DGN45ec1e834f4baf0922581c526120633c http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0029456 http://rdf.disgenet.org/resource/gda/DGN45ec1e834f4baf0922581c526120633c http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001121 http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_provenance http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_assertion http://purl.org/dc/terms/description [The mature osteocyte expresses the protein sclerostin, a negative regulator of bone mass.➤ In normal physiologic states, the protein sclerostin acts on osteoblasts at the surface of bone and is differentially expressed in response to mechanical loading, inflammatory molecules such as prostaglandin E2, and hormones such as parathyroid hormone and estrogen.➤ Pathologically, sclerostin dysregulation has been observed in osteoporosis-related fractures, failure of implant osseous integration, metastatic bone disease, and select genetic diseases of bone mass.➤ An antibody that targets sclerostin, decreasing endogenous levels of sclerostin while increasing bone mineral density, is currently in phase-III clinical trials.➤ The osteocyte has emerged as a versatile, indispensable bone cell.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/25274791 http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v3.0.0/void/befree-20150227 http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v3.0.0/void/befree-20150227 http://purl.org/pav/importedOn 2015-02-27 http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://purl.org/dc/terms/created 2015-08-25T14:46:49+02:00 http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v3.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v3.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP900124.RArZEmjDIJGy86hLErOwK1EVrcos1nsiip0gv4K6CKgEo http://purl.org/pav/version v3.0.0.0 http://rdf.disgenet.org/v3.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v3.0.0