@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP475435.RArLqZtOBiLYUe_bAVAleVsga8zkmdSMe8MbIPe-6R-44130_head { this: np:hasAssertion dgn-np:NP475435.RArLqZtOBiLYUe_bAVAleVsga8zkmdSMe8MbIPe-6R-44130_assertion; np:hasProvenance dgn-np:NP475435.RArLqZtOBiLYUe_bAVAleVsga8zkmdSMe8MbIPe-6R-44130_provenance; np:hasPublicationInfo dgn-np:NP475435.RArLqZtOBiLYUe_bAVAleVsga8zkmdSMe8MbIPe-6R-44130_publicationInfo; a np:Nanopublication . dgn-np:NP475435.RArLqZtOBiLYUe_bAVAleVsga8zkmdSMe8MbIPe-6R-44130_assertion a np:Assertion . dgn-np:NP475435.RArLqZtOBiLYUe_bAVAleVsga8zkmdSMe8MbIPe-6R-44130_provenance a np:Provenance . dgn-np:NP475435.RArLqZtOBiLYUe_bAVAleVsga8zkmdSMe8MbIPe-6R-44130_publicationInfo a np:PublicationInfo . } dgn-np:NP475435.RArLqZtOBiLYUe_bAVAleVsga8zkmdSMe8MbIPe-6R-44130_assertion { miriam-gene:4513 a ncit:C16612 . lld:C0025202 a ncit:C7057 . dgn-gda:DGN046f3a9408edad1b6e88cb28db6e1fdd sio:SIO_000628 miriam-gene:4513, lld:C0025202; a sio:SIO_001121 . } dgn-np:NP475435.RArLqZtOBiLYUe_bAVAleVsga8zkmdSMe8MbIPe-6R-44130_provenance { dgn-np:NP475435.RArLqZtOBiLYUe_bAVAleVsga8zkmdSMe8MbIPe-6R-44130_assertion dcterms:description "[In immortalized rat brain GP8.3 EC cultures, conditioned media (CM) prepared from SK-MEL28 and OCM-1 melanoma cells significantly enhanced arachidonic acid release, cytosolic phospholipase A(2) (cPLA(2)) and Ca(+)-independent phospholipase A(2) (iPLA(2)) specific activities, and cell growth by 24 h. Inhibitors such as wortmannin and LY294002 (vs. PI3 kinase activity), AACOCF(3), (vs. cPLA(2) and iPLA(2)), PD98059 (vs. ERK1/2 activity) and NS-398 (vs. cyclooxygenase-2 activity, COX-2) were all able to block cell proliferation and motility determined using a scratch wound healing assay in melanoma CMs-stimulated EC monolayers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:19747926; prov:wasDerivedFrom dgn-void:befree-20140225; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP475435.RArLqZtOBiLYUe_bAVAleVsga8zkmdSMe8MbIPe-6R-44130_publicationInfo { this: dcterms:created "2014-10-02T12:36:45+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetrdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v2.1.0.0" . dgn-void:disgenetrdf pav:version "v2.1.0" . }