. . . . . . . . . . . . . . . . . . "kin(p(HGNC:YES1)) => kin(p(HGNC:EGFR))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "Activated Yes rapidly associates with the EGFR and triggers its phosphorylation at tyrosine residues Tyr845 and Tyr1173. EGFRTyr845 is a known Src target (52), whereas Tyr1173 reflects an activating autophosphorylation site of the EGFR (53). Yes inhibition by SU6656 abolishes EGFR phosphorylation at both sites, whereas AG1478 inhibits EGFR-Tyr1173 phosphorylationbut not phosphorylation at Tyr845. These findings suggest that Yes activates the EGFR at Tyr845, which is followed by activating autophosphorylation at Tyr1173." . . "Selventa" . . . . "2014-07-03T14:32:45.305+02:00"^^ . . .