http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#Head http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4 http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#assertion http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4 http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#provenance http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4 http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#pubinfo http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#assertion http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_2 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0003824 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=6343 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_3 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=2097 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_3 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_1 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#assertion http://www.w3.org/2000/01/rdf-schema#label cat(p(HGNC:KITLG)) -> p(HGNC:CMA1) http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_6 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_5 http://www.w3.org/ns/prov#value BACKGROUND: In vitro-derived human mast cells exhibit different properties, depending in part on the source of progenitor cells. Most investigations have used fetal liver, cord blood or peripheral blood. Few have used adult bone marrow. OBJECTIVE: Human mast cells derived in vitro from the CD34(+) progenitors in bone marrow and cord blood that had been cultured with recombinant human stem cell factor (rhSCF) and recombinant human interleukin-6 (rhIL-6) were compared. METHODS AND RESULTS: After 12 weeks of culture, nearly all of the cells were mast cells, and nearly all of these had cytoplasmic granules containing both tryptase and chymase (MCTC type), stained metachromatically with acidic toluidine blue, and expressed CD117 on the cell surface. Both tryptase protein and mRNA were detected by two weeks of culture. Chymase mRNA and protein were detected at 4 weeks but not at 2 weeks of culture. Different forms of tryptase (both total and ?-tryptase) in HBMMC were measured by sandwich ELISA http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/12047434 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/12047434 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#_5 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4#pubinfo http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4 http://purl.org/dc/terms/created 2014-07-03T14:31:49.836+02:00 http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4 http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAqJC_jONJKVbTur4WArzKEvETDEcSh0zJdseQCDrAjw4 http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234