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[The potentiator Kalydecoâ„¢ (also known as Ivacaftor or VX-770), developed by Vertex Pharmaceuticals, has been recently approved by the US FDA and the European Medicines Agency (EMA) for the treatment of CF patients carrying at least one CFTR allele with the p.Gly551Asp mutation (2-5 % of all patients).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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