. . . . . . . . . . . . . . . . . . "phos(p(HGNC:PTEN)) -| kin(complex(SCOMP:\"p85/p110 PI3Kinase Complex\"))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "The PI3K pathway is negatively regulated by PTEN (phosphatase and TENsin homolog), which converts PIP3 in PIP2, preventing PKB activation and Bad phosphorylation/sequestration. Thus PTEN is considered as a tumor suppressor gene. It has been shown that NS-398 was able to increase the level of PTEN in human gastric carcinoma cell line MKN45 [114]. " . . "Selventa" . . . . "2014-07-03T14:33:38.734+02:00"^^ . . .