[ {
  "@graph" : [ {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY",
    "@type" : [ "http://www.nanopub.org/nschema#Nanopublication" ],
    "http://www.nanopub.org/nschema#hasAssertion" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#assertion"
    } ],
    "http://www.nanopub.org/nschema#hasProvenance" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#provenance"
    } ],
    "http://www.nanopub.org/nschema#hasPublicationInfo" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#pubinfo"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#Head"
}, {
  "@graph" : [ {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_1",
    "@type" : [ "http://amigo.geneontology.org/amigo/term/GO:0016301" ],
    "http://semanticscience.org/resource/SIO_000139" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_2"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_2",
    "@type" : [ "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080" ],
    "http://purl.obolibrary.org/obo/RO_0002204" : [ {
      "@id" : "http://resource.belframework.org/belframework/20131211/namespace/selventa-protein-families/MEK1%2F2%20Family"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_3",
    "@type" : [ "http://amigo.geneontology.org/amigo/term/GO:0016301" ],
    "http://semanticscience.org/resource/SIO_000139" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_4"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_4",
    "@type" : [ "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080" ],
    "http://purl.obolibrary.org/obo/RO_0002204" : [ {
      "@id" : "http://resource.belframework.org/belframework/20131211/namespace/selventa-protein-families/MAPK%20Erk1%2F2%20Family"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_5",
    "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ],
    "http://purl.obolibrary.org/obo/BFO_0000066" : [ {
      "@id" : "http://purl.obolibrary.org/obo/CL_0002328"
    }, {
      "@id" : "http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_3"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ {
      "@id" : "http://www.selventa.com/vocabulary/increases"
    } ],
    "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_1"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#assertion",
    "http://www.w3.org/2000/01/rdf-schema#label" : [ {
      "@value" : "kin(p(SFAM:\"MEK1/2 Family\")) -> kin(p(SFAM:\"MAPK Erk1/2 Family\"))"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#assertion"
}, {
  "@graph" : [ {
    "@id" : "http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel",
    "http://purl.org/dc/elements/1.1/description" : [ {
      "@value" : "Approximately 61,000 statements."
    } ],
    "http://purl.org/dc/elements/1.1/rights" : [ {
      "@value" : "Copyright (c) 2011-2012, Selventa. All rights reserved."
    } ],
    "http://purl.org/dc/elements/1.1/title" : [ {
      "@value" : "BEL Framework Large Corpus Document"
    } ],
    "http://purl.org/pav/authoredBy" : [ {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_7"
    } ],
    "http://purl.org/pav/version" : [ {
      "@value" : "20131211"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_6",
    "http://www.w3.org/ns/prov#value" : [ {
      "@value" : "To determine the mechanisms linking MMP-12 and inflammation, we examined the effect of recombinant human MMP-12 (rhMMP-12) catalytic domain on IL-8/CXCL8 production in cultured human airway epithelial (A549) cells. Stimulation with rhMMP-12 resulted in a concentration-dependent IL-8/CXCL8 synthesis 6 h later.. rhMMP-12 induced transient, peaking at 5 min, activation of ERK1/2. Selective MEK inhibitors (U0126 and PD-98059) blocked both IL-8/CXCL8 release and ERK1/2 phosphorylation. IL-8/CXCL8 induction and ERK1/2 activation were preceded by EGF receptor (EGFR) tyrosine phosphorylation, within 2 min, and reduced by selective EGFR tyrosine kinase inhibitors (AG-1478 and PD168393) by a neutralizing EGFR antibody and by small interfering RNA oligonucleotides directed against EGFR, implicating EGFR activation."
    } ],
    "http://www.w3.org/ns/prov#wasQuotedFrom" : [ {
      "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/18390828"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_7",
    "http://www.w3.org/2000/01/rdf-schema#label" : [ {
      "@value" : "Selventa"
    } ]
  }, {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#assertion",
    "http://www.w3.org/ns/prov#hadPrimarySource" : [ {
      "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/18390828"
    } ],
    "http://www.w3.org/ns/prov#wasDerivedFrom" : [ {
      "@id" : "http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel"
    }, {
      "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#_6"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#provenance"
}, {
  "@graph" : [ {
    "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY",
    "http://purl.org/dc/terms/created" : [ {
      "@type" : "http://www.w3.org/2001/XMLSchema#dateTime",
      "@value" : "2014-07-03T14:33:19.895+02:00"
    } ],
    "http://purl.org/pav/createdBy" : [ {
      "@id" : "http://orcid.org/0000-0001-6818-334X"
    }, {
      "@id" : "http://orcid.org/0000-0002-1267-0234"
    } ]
  } ],
  "@id" : "http://www.tkuhn.ch/bel2nanopub/RAq6erjtcfTxXoa9Xq_RWWu9K_VwsGuZXt6__f4iLPxHY#pubinfo"
} ]