@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP305125.RAq2mUhf6vLrcM8Ry1FBEOfylIARwSD_RBpuLjyGulOr4> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v3.0.0/void/> .

dgn-np:NP305125.RAq2mUhf6vLrcM8Ry1FBEOfylIARwSD_RBpuLjyGulOr4130_head {
  this: np:hasAssertion dgn-np:NP305125.RAq2mUhf6vLrcM8Ry1FBEOfylIARwSD_RBpuLjyGulOr4130_assertion;
    np:hasProvenance dgn-np:NP305125.RAq2mUhf6vLrcM8Ry1FBEOfylIARwSD_RBpuLjyGulOr4130_provenance;
    np:hasPublicationInfo dgn-np:NP305125.RAq2mUhf6vLrcM8Ry1FBEOfylIARwSD_RBpuLjyGulOr4130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP305125.RAq2mUhf6vLrcM8Ry1FBEOfylIARwSD_RBpuLjyGulOr4130_assertion a np:Assertion .
  
  dgn-np:NP305125.RAq2mUhf6vLrcM8Ry1FBEOfylIARwSD_RBpuLjyGulOr4130_provenance a np:Provenance .
  
  dgn-np:NP305125.RAq2mUhf6vLrcM8Ry1FBEOfylIARwSD_RBpuLjyGulOr4130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP305125.RAq2mUhf6vLrcM8Ry1FBEOfylIARwSD_RBpuLjyGulOr4130_assertion {
  miriam-gene:1029 a ncit:C16612 .
  
  lld:C0032002 a ncit:C7057 .
  
  dgn-gda:DGN00ff42ca2c09ae71aff53d676395d72e sio:SIO_000628 miriam-gene:1029, lld:C0032002;
    a sio:SIO_001124 .
}

dgn-np:NP305125.RAq2mUhf6vLrcM8Ry1FBEOfylIARwSD_RBpuLjyGulOr4130_provenance {
  dgn-np:NP305125.RAq2mUhf6vLrcM8Ry1FBEOfylIARwSD_RBpuLjyGulOr4130_assertion dcterms:description
      "[Our results suggest that inactivation of the RB1 pathway may play a causal role in pituitary tumorigenesis, with hypermethylation of the p16(INK4a) gene being the most common deregulation, and further provide evidence that RB1 and p16(INK4a) methylations tend to be mutually exclusive but occasionally coincide with p15(INK4b) methylation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:15892297;
    prov:wasDerivedFrom dgn-void:befree-20150227;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20150227 pav:importedOn "2015-02-27"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP305125.RAq2mUhf6vLrcM8Ry1FBEOfylIARwSD_RBpuLjyGulOr4130_publicationInfo {
  this: dcterms:created "2015-08-25T14:40:35+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v3.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v3.0.0" .
}