@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP186625.RApakedxJ18OxRqWCISw7U8suC0skWgoDXKP0oLuDwVZI> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP186625.RApakedxJ18OxRqWCISw7U8suC0skWgoDXKP0oLuDwVZI130_head {
  this: np:hasAssertion dgn-np:NP186625.RApakedxJ18OxRqWCISw7U8suC0skWgoDXKP0oLuDwVZI130_assertion;
    np:hasProvenance dgn-np:NP186625.RApakedxJ18OxRqWCISw7U8suC0skWgoDXKP0oLuDwVZI130_provenance;
    np:hasPublicationInfo dgn-np:NP186625.RApakedxJ18OxRqWCISw7U8suC0skWgoDXKP0oLuDwVZI130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP186625.RApakedxJ18OxRqWCISw7U8suC0skWgoDXKP0oLuDwVZI130_assertion a np:Assertion .
  
  dgn-np:NP186625.RApakedxJ18OxRqWCISw7U8suC0skWgoDXKP0oLuDwVZI130_provenance a np:Provenance .
  
  dgn-np:NP186625.RApakedxJ18OxRqWCISw7U8suC0skWgoDXKP0oLuDwVZI130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP186625.RApakedxJ18OxRqWCISw7U8suC0skWgoDXKP0oLuDwVZI130_assertion {
  miriam-gene:999 a ncit:C16612 .
  
  lld:C0685938 a ncit:C7057 .
  
  dgn-gda:DGN2d0a540bd00e6f1cdbc5ff15f263d33b sio:SIO_000628 miriam-gene:999, lld:C0685938;
    a sio:SIO_001121 .
}

dgn-np:NP186625.RApakedxJ18OxRqWCISw7U8suC0skWgoDXKP0oLuDwVZI130_provenance {
  dgn-np:NP186625.RApakedxJ18OxRqWCISw7U8suC0skWgoDXKP0oLuDwVZI130_assertion dcterms:description
      "[The results showed that; (i) genotypes with the +54C allele (C/C or C/T) significantly increased the risk of developing both ESCC and GCA compared to the +54T/T genotype (age and gender adjusted odds ratio [OR] = 1.45 and 2.28, 95% confidence interval [CI] = 1.06-1.99 and 1.58-3.30, respectively), and this association was significant only among non-smokers (OR = 1.68 and 2.64, 95% CI = 1.01-2.80 and 1.43-4.87 for ESCC and GCA, respectively), and individuals without a family history of upper gastrointestinal cancer (OR = 2.63 and 2.97, 95% CI = 1.36-5.10 and 95% CI = 1.32-6.68 for ESCC and GCA, respectively); (ii) compared with the -347G/G genotype, the -347GA and GA/GA genotypes significantly increased the risk of developing GCA (OR = 1.45, 95 % CI = 1.03-2.04); (iii) there was a significant association of CDH1-160C/-347G/+54C and -160C/-347GA/+54C haplotypes with the development of GCA, compared with the -160C/-347G/+54T haplotype (OR = 1.80 and 2.21, 95% CI = 1.33-2.44 and 1.43-3.42, respectively); and (iv) the influence of CDH1 SNP on the depth of tumor invasion and lymphatic metastasis in ESCC and GCA patients was not observed in this study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:18197935;
    prov:wasDerivedFrom dgn-void:befree-20140225;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP186625.RApakedxJ18OxRqWCISw7U8suC0skWgoDXKP0oLuDwVZI130_publicationInfo {
  this: dcterms:created "2014-10-02T12:33:42+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v2.1.0.0" .
  
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}